Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Elizaveta Fasler‐Kan"'
Autor:
Maryam Abooali, Inna M. Yasinska, Stephanie Schlichtner, Sabrina Ruggiero, Steffen M. Berger, Dietmar Cholewa, Milan Milošević, Andreas Bartenstein, Elizaveta Fasler-Kan, Vadim V. Sumbayev
Publikováno v:
Translational Oncology, Vol 39, Iss , Pp 101805- (2024)
Malignant transformation of human cells is associated with their re-programming which results in uncontrolled proliferation and in the same time biochemical activation of immunosuppressive pathways which form cancer immune evasion machinery. However,
Externí odkaz:
https://doaj.org/article/8017fc6b56d84459acc2a497ce18cf29
Autor:
Stephanie Schlichtner, Inna M. Yasinska, Elena Klenova, Maryam Abooali, Gurprit S. Lall, Steffen M. Berger, Sabrina Ruggiero, Dietmar Cholewa, Milan Milošević, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Vadim V. Sumbayev
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTMalignant tumors often escape anticancer immune surveillance by suppressing the cytotoxic functions of T lymphocytes. While many of these immune evasion networks include checkpoint proteins, small molecular weight compounds, such as the amino
Externí odkaz:
https://doaj.org/article/af8e958bbeec46739a4b45819fd24cbb
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/63fed4272cb04f45843c9bbf8fa3422e
Autor:
Stephanie Schlichtner, Inna M Yasinska, Gurprit S Lall, Steffen M Berger, Sabrina Ruggiero, Dietmar Cholewa, Nijas Aliu, Bernhard F Gibbs, Elizaveta Fasler-Kan, Vadim V Sumbayev
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background Galectin-9 is a member of the family of lectin proteins and crucially regulates human immune responses, particularly because of its ability to suppress the anticancer activities of T lymphocytes and natural killer cells. Recent evidence de
Externí odkaz:
https://doaj.org/article/fda2b5b4fd00456fae87452cb2fa1b43
Autor:
Gaetan Aime Noubissi Nzeteu, Stephanie Schlichtner, Sulamith David, Aylin Ruppenstein, Elizaveta Fasler-Kan, Ulrike Raap, Vadim V. Sumbayev, Bernhard F. Gibbs, N. Helge Meyer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Recently, the V-domain immunoglobulin suppressor of T-cell activation (VISTA) was identified as a negative immune checkpoint regulator (NCR) that is mainly expressed in hematopoietic cells. Preclinical studies have shown that VISTA blockade results i
Externí odkaz:
https://doaj.org/article/efc8ca0dc2af46be88b2cef44b04ee93
Autor:
Stephanie Schlichtner, Inna M. Yasinska, Sabrina Ruggiero, Steffen M. Berger, Nijas Aliu, Mateja Prunk, Janko Kos, N. Helge Meyer, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Vadim V. Sumbayev
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Immune checkpoint proteins play crucial roles in human embryonic development but are also used by cancer cells to escape immune surveillance. These proteins and biochemical pathways associated with them form a complex machinery capable of blocking th
Externí odkaz:
https://doaj.org/article/df9cbb22cd0c4b25850127b6e31a3396
Autor:
Galina Nugumanova, Eugene D. Ponomarev, Sholpan Askarova, Elizaveta Fasler-Kan, Natasha S. Barteneva
Publikováno v:
Toxins, Vol 15, Iss 3, p 233 (2023)
Cyanobacteria produce a wide range of structurally diverse cyanotoxins and bioactive cyanopeptides in freshwater, marine, and terrestrial ecosystems. The health significance of these metabolites, which include genotoxic- and neurotoxic agents, is con
Externí odkaz:
https://doaj.org/article/cb77dc61224c4b4582a4c0b4dd78308f
Autor:
Anette Teo Hansen Selnø, Stephanie Schlichtner, Inna M. Yasinska, Svetlana S. Sakhnevych, Walter Fiedler, Jasmin Wellbrock, Steffen M. Berger, Elena Klenova, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Vadim V. Sumbayev
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
High mobility group box 1 (HMGB1) is a non-histone protein which is predominantly localised in the cell nucleus. However, stressed, dying, injured or dead cells can release this protein into the extracellular matrix passively. In addition, HMGB1 rele
Externí odkaz:
https://doaj.org/article/c04a7804921742bfb246d9e415af1d0d
Autor:
Inna M. Yasinska, N. Helge Meyer, Stephanie Schlichtner, Rohanah Hussain, Giuliano Siligardi, Maxwell Casely-Hayford, Walter Fiedler, Jasmin Wellbrock, Cloe Desmet, Luigi Calzolai, Luca Varani, Steffen M. Berger, Ulrike Raap, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Vadim V. Sumbayev
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Acute myeloid leukemia (AML), a blood/bone marrow cancer, is a severe and often fatal malignancy. AML cells are capable of impairing the anti-cancer activities of cytotoxic lymphoid cells. This includes the inactivation of natural killer (NK) cells a
Externí odkaz:
https://doaj.org/article/fde3b7a88f6a40a58578f302b9d89082
Autor:
Khaled Mukaddam, Monika Astasov-Frauenhoffer, Elizaveta Fasler-Kan, Laurent Marot, Marcin Kisiel, Roland Steiner, Fabien Sanchez, Ernst Meyer, Joachim Köser, Michael M. Bornstein, Sebastian Kühl
Publikováno v:
Nanomaterials, Vol 12, Iss 7, p 1065 (2022)
Aim(s): The aim of the study was to fabricate a nanospike surface on a titanium alloy surface using a newly established method of low-energy helium ion bombardment. Various methods to achieve nanospike formation on titanium have been introduced recen
Externí odkaz:
https://doaj.org/article/fc4174c8b1354cf6a3389da7ad32afb1