Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Elizaveta A. Dutysheva"'
Autor:
Vladimir F. Lazarev, Elizaveta A. Dutysheva, Igor E. Kanunikov, Irina V. Guzhova, Boris A. Margulis
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 312 (2023)
The amyloid concept of Alzheimer’s disease (AD) assumes the β-amyloid peptide (Aβ) as the main pathogenic factor, which injures neural and other brain cells, causing their malfunction and death. Although Aβ has been documented to exert its cytot
Externí odkaz:
https://doaj.org/article/51db7dc47eed4c469fe88ffaca5c3901
Autor:
Elizaveta A. Dutysheva, Irina A. Utepova, Maria A. Trestsova, Alexander S. Anisimov, Valery N. Charushin, Oleg N. Chupakhin, Boris A. Margulis, Irina V. Guzhova, Vladimir F. Lazarev
Publikováno v:
Data in Brief, Vol 39, Iss , Pp 107562- (2021)
These data are related to our previous paper “Synthesis and approbation of new neuroprotective chemicals of pyrrolyl- and indolylazine classes in a cell model of Alzheimer's disease” (Dutysheva et al., 2021), in which we demonstrate neuroprotecti
Externí odkaz:
https://doaj.org/article/7b9e6d3cd84847e3a178db7ff8b6c459
Autor:
Vladimir F. Lazarev, Elizaveta A. Dutysheva, Elena R. Mikhaylova, Maria A. Trestsova, Irina A. Utepova, Oleg N. Chupakhin, Boris A. Margulis, Irina V. Guzhova
Publikováno v:
Molecules, Vol 27, Iss 24, p 8950 (2022)
The risk of progression of most sporadic neurodegenerative diseases, including Alzheimer’s disease, increases with age. Traditionally, this is associated with a decrease in the efficiency of cell protection systems, in particular, molecular chapero
Externí odkaz:
https://doaj.org/article/53b1cce0fb37433b9fcffbf34253d2ed
Autor:
Elizaveta A. Dutysheva, Elena R. Mikhaylova, Maria A. Trestsova, Alexander I. Andreev, Danila Yu. Apushkin, Irina A. Utepova, Polina O. Serebrennikova, Eugenia A. Akhremenko, Nikolay D. Aksenov, Elizaveta I. Bon’, Sergey M. Zimatkin, Oleg N. Chupakhin, Boris A. Margulis, Irina V. Guzhova, Vladimir F. Lazarev
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 7 (2022)
The recovery period after traumatic brain injury (TBI) is often complicated by secondary damage that may last for days or even months after trauma. Two proteins, Hsp70 and glyceraldehyde-3-phosphate dehydrogenase (GAPDH), were recently described as m
Externí odkaz:
https://doaj.org/article/af9f729ef87b4ef4b389249d5ce0fbec
Autor:
Vladimir F. Lazarev, Elizaveta A. Dutysheva, Elena Y. Komarova, Irina V. Guzhova, Boris A. Margulis
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 899-902 (2018)
These data are related to our paper “GAPDH-targeted therapy – a new approach for secondary damage after traumatic brain injury on rats” (Lazarev et al., In press), in which we explore the role of exogenous GAPDH in traumatic brain injury-induce
Externí odkaz:
https://doaj.org/article/b0bd037f9222433c99c1fecfd96f024f
Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress
Autor:
Marina A. Mikeladze, Elizaveta A. Dutysheva, Victor G. Kartsev, Boris A. Margulis, Irina V. Guzhova, Vladimir F. Lazarev
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1520 (2021)
Hypoxia, which commonly accompanies tumor growth, depending on its strength may cause the enhancement of tumorigenicity of cancer cells or their death. One of the proteins targeted by hypoxia is glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and w
Externí odkaz:
https://doaj.org/article/495eddc8051a4b5f9fbd24bd7426462b
Autor:
Elizaveta A. Dutysheva, Marina A. Mikeladze, Maria A. Trestsova, Nikolay D. Aksenov, Irina A. Utepova, Elena R. Mikhaylova, Roman V. Suezov, Valery N. Charushin, Oleg N. Chupakhin, Irina V. Guzhova, Boris A. Margulis, Vladimir F. Lazarev
Publikováno v:
Pharmaceutics, Vol 12, Iss 5, p 414 (2020)
Traumatic brain injury (TBI) often causes massive brain cell death accompanied by the accumulation of toxic factors in interstitial and cerebrospinal fluids. The persistence of the damaged brain area is not transient and may occur within days and wee
Externí odkaz:
https://doaj.org/article/a05f2bb7c211409b9acbc35059a6f2a4
Autor:
Marina A. Mikeladze, M. A. Trestsova, Elizaveta A. Dutysheva, Irina V. Guzhova, Vladimir F. Lazarev, Oleg N. Chupakhin, Boris A. Margulis, Irina A. Utepova
Publikováno v:
Cell and Tissue Biology. 14:52-56
Traumatic brain injury (TBI) induces multiple pathological processes affecting various brain cells. the accumulation of toxic factors in interstitial and cerebrospinal fluid may be a consequence of TBI and massive cell death. The accumulation process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82dca15329cdce5344e115e2acd33c49
https://doi.org/10.1134/s1990519x20010071
https://doi.org/10.1134/s1990519x20010071
Autor:
Oleg N. Chupakhin, Alexander S. Anisimov, Elizaveta A. Dutysheva, Irina V. Guzhova, Boris A. Margulis, Irina A. Utepova, Maria A. Trestsova, Vladimir F. Lazarev, Valery N. Charushin
Publikováno v:
Data in Brief
Data in Brief, Vol 39, Iss, Pp 107562-(2021)
Data in Brief, Vol 39, Iss, Pp 107562-(2021)
These data are related to our previous paper “Synthesis and approbation of new neuroprotective chemicals of pyrrolyl- and indolylazine classes in a cell model of Alzheimer's disease” (Dutysheva et al., 2021), in which we demonstrate neuroprotecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23a8ae1ca07407bd001cb938377c584
https://pubmed.ncbi.nlm.nih.gov/34825031
https://pubmed.ncbi.nlm.nih.gov/34825031
Autor:
Irina A. Utepova, Boris A. Margulis, Oleg N. Chupakhin, Irina V. Guzhova, Valery N. Charushin, Alexander S. Anisimov, Elizaveta A. Dutysheva, Vladimir F. Lazarev, Maria A. Trestsova
Publikováno v:
European journal of medicinal chemistry. 222
One of the major causes of neurodegeneration in the pathogenesis of Alzheimer's disease is the accumulation of cytotoxic amyloid species within the intercellular compartments of the brain. The efficacy of the anti-proteotoxic mechanism based on the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b526877ab05ab77cc30fdd38b12a52
https://pubmed.ncbi.nlm.nih.gov/34087544
https://pubmed.ncbi.nlm.nih.gov/34087544