Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Elizabeth Zebrowski"'
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Akademický článek
Transient elastography score is elevated during rheumatoid factor-positive chronic hepatitis C virus infection and rheumatoid factor decline is highly variable over the course of direct-acting antiviral therapy.
Autor: Ann W N Auma, Corinne Kowal, Carey L Shive, Alyssa Lange, Sofi Damjanovska, Elizabeth Zebrowski, Elane Reyes, Leonard Calabrese, Lenche Kostadinova, Yngve Falck-Ytter, Maya Mattar, Donald D Anthony
Publikováno v: PLoS ONE, Vol 17, Iss 4, p e0267512 (2022)
BackgroundElevated rheumatoid factor (RF) levels and systemic immune activation are highly prevalent during chronic hepatitis C virus (HCV) infection. Direct-acting antiviral (DAA) therapy has been associated with normalization of various soluble imm
Externí odkaz: https://doaj.org/article/ce466ae99a50403cb903760ee2886fb4
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2
Akademický článek
During HCV DAA Therapy Plasma Mip1B, IP10, and miRNA Profile Are Distinctly Associated with Subsequent Diagnosis of Hepatocellular Carcinoma: A Pilot Study
Autor: Sofi Damjanovska, Hawwa Alao, Elizabeth Zebrowski, Corinne Kowal, Lenche Kostadinova, Perica Davitkov, Yngve Falck-Ytter, Carey L. Shive, Michael Cartwright, Brian Richardson, David Wald, Mark Cameron, Saba Valadkhan, Donald D. Anthony
Publikováno v: Biology, Vol 11, Iss 9, p 1262 (2022)
Background: Hepatitis C virus (HCV) therapy lowers risk of hepatocellular carcinoma (HCC). Little is known about factors driving/preceding HCC in treated persons. MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) regulate host response and pathog
Externí odkaz: https://doaj.org/article/131cff5a4bf4481891dfcc198f640398
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3
Akademický článek
Naïve CD4+ T Cell Lymphopenia and Apoptosis in Chronic Hepatitis C Virus Infection Is Driven by the CD31+ Subset and Is Partially Normalized in Direct-Acting Antiviral Treated Persons
Autor: Ann W.N. Auma, Carey L. Shive, Alyssa Lange, Sofi Damjanovska, Corinne Kowal, Elizabeth Zebrowski, Pushpa Pandiyan, Brigid Wilson, Robert C. Kalayjian, David H. Canaday, Donald D. Anthony
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
BackgroundThe mechanisms underlying naïve CD4+ lymphopenia during chronic Hepatitis C Virus (HCV) infection are unclear. Whether direct-acting antiviral (DAA) therapy restores peripheral naïve CD4+ T cell numbers and function is unknown.MethodsWe e
Externí odkaz: https://doaj.org/article/639e6fbfad364c11bc4487545f3d378e
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4
Akademický článek
Soluble Markers of Immune Activation Differentially Normalize and Selectively Associate with Improvement in AST, ALT, Albumin, and Transient Elastography During IFN-Free HCV Therapy
Autor: Lenche Kostadinova, Carey L. Shive, Elizabeth Zebrowski, Brianna Fuller, Kelsey Rife, Amy Hirsch, Anita Compan, Anita Moreland, Yngve Falck-Ytter, Daniel L. Popkin, Donald D. Anthony
Publikováno v: Pathogens and Immunity, Vol 3, Iss 1, Pp 149-163 (2018)
Background: During chronic hepatitis C virus (HCV) infection, Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) levels mark active liver inflammation and tissue damage, while albumin reflects synthetic liver function and nutritional
Externí odkaz: https://doaj.org/article/a651cb373a704c528bb45bc7a62bed87
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6
Chronic HCV infection, HCV/HIV coinfection and older age are independently associated with naïve CD4+CD31+ lymphopenia
Autor: Ann Auma, Corinne Kowal, Elizabeth Zebrowski, Sofi Damjanovska, Carey Shive, Melissa Osborne, Robert Kalayjian, Donald D Anthony
Publikováno v: The Journal of Immunology. 202:120.32-120.32
Background Chronic Hepatitis C virus (HCV), HCV/HIV and aging are known to predispose to impaired immunity to vaccines, new infections and cancers. Naïve CD4+CD31+ lymphopenia is exhibited in all three conditions, and may be one contributor to impai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6701d845748b42ebebcebbfda8fca30
https://doi.org/10.4049/jimmunol.202.supp.120.32
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7
Regulation of Interferon-stimulated gene BST2 by a lncRNA transcribed from a shared bidirectional promoter
Autor: Dawid Krokowski, Raul Jobava, Maria Hatzoglou, Donald D. Anthony, Hiroto Kambara, Elizabeth Zebrowski, Saba Valadkhan, Lalith Gunawardane, Lenche Kostadinova
Publikováno v: Frontiers in Immunology, Vol 5 (2015)
Frontiers in Immunology
Recent genome-wide studies have revealed the presence of thousands of long non-protein-coding RNAs (lncRNAs), some of which may play critical roles in the cell. We have previously shown that a large number of lncRNAs show differential expression in r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e08f113734643cc71c3f056d1b0ba88
http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00676/full
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8
Long noncoding RNA (lncRNA) Negative Regulator of Interferon Response (NRIR) is induced along with other Interferon Induced mRNA in primary NK cells of uninfected and HCV infected persons
Autor: Elizabeth Zebrowski, Marina Barriocanal, Puri Fortes, Saba Valadkhan, Donald D Anthony
Publikováno v: The Journal of Immunology. 198:75.4-75.4
Background Natural Killer cells are thought to participate in control of HCV during the early phase of infection (first 6 months) and during IFN containing HCV therapy. At the same time, IFN resistance underlies wide variability in therapeutic respon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8aaf3e3e37ae94252b97828483ce3b4f
https://doi.org/10.4049/jimmunol.198.supp.75.4
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