Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Elizabeth Waterfield"'
Autor:
Alice J. Canaan, Anna M. Richter, Ashok K. Jain, Elizabeth Waterfield, Beth Anne Allison, Julia G. Levy
Publikováno v:
Photochemistry and Photobiology. 57:1000-1006
Biodistribution studies were carried out on 14C-labeled benzoporphyrin derivative monoacid ring A (BPD), which had been formulated as a unilamellar liposome or taken from a stock solution in dimethyl sulfoxide diluted into phosphate-buffered saline i
Autor:
Julia G. Levy, Alice J. Canaan, Ashok K. Jain, Elizabeth Waterfield, Ethan Sternberg, Anna M. Richter
Publikováno v:
Biochemical Pharmacology. 43:2349-2358
Benzoporphyrin derivative, monoacid ring A (BPD-MA), currently in clinical trials as a photosensitizer for photodynamic therapy for cancer, consists of two regioisomers (A1 and A2) present in equal proportions. The contribution of the regioisomers to
In vitro EVALUATION OF PHOTOTOXIC PROPERTIES OF FOUR STRUCTURALLY RELATED BENZOPORPHYRIN DERIVATIVES
Autor:
Ethan Sternberg, David Dolphin, Julia G. Levy, Elizabeth Waterfield, Ashok K. Jain, Anna M. Richter
Publikováno v:
Photochemistry and Photobiology. 52:495-500
Four structural analogs of benzoporphyrin derivative (BPD) have been studied and compared for photosensitizing activity in vitro. All analogs have an identical reduced tetrapyrrol porphyrin ring, and differ by the position of a cyclohexadiene ring (f
Publikováno v:
International journal of immunopharmacology. 17(1)
The porphyrin photosensitizer, Photofrin® porfimer sodium (Photofrin®), has been widely studied for its capacity to evoke destruction of malignant tissues. In addition to its photosensitizing properties, Photofrin® may exert myelostimulatory effec
Autor:
Claire Smits, Martin Renke, Robert D. Bower, Julia G. Levy, Elizabeth Waterfield, Michele D. Gervais, Michael S. Stonefield
Publikováno v:
Photochemistry and photobiology. 60(4)
Benzoporphyrin derivative monoacid ring A (BPD-MA) is a chlorin-like photosensitizer currently in clinical trials for cancer and psoriasis. It has maximal absorption peaks at both 630 and 690 nm and can be activated at both these wavelengths. In vitr
Autor:
Vincent Salvatori, Levy Julia G, Claire Smits, Luciann Hruza, Anna M. Richter, Harvey Lui, Elizabeth Waterfield, R. Rox Anderson
Publikováno v:
SPIE Proceedings.
Benzoporohyrin derivative monoacid ring A (BPD) is a lipophilic photosensitizer with a maximum absorption peak at 690 nm. When liposomally formulated, it distributes in human plasma almost exclusively to the lipoprotein fraction. In experimental anim
Autor:
Julia G. Levy, Elizabeth Waterfield, Lily Xie, Martin Renke, Robert A. Sorrenti, David W. C. Hunt
Publikováno v:
Immunopharmacology and immunotoxicology. 16(1)
Porphyrins are a group of organic compounds involved in a wide spectrum of fundamental biological processes. Non-metallic, naturally occurring and synthetic porphyrin derivatives may produce cytotoxic effects in malignant or normal tissues exposed to
Publikováno v:
Photochemistry and photobiology. 54(5)
The influence of lipoprotein association on in vitro tumor cell killing and in vivo tumor photosensitization with benzoporphyrin derivative (BPD) has been investigated in M-1 tumor bearing mice. The association of benzoporphyrin mono acid ring A with
Publikováno v:
Advances in Photochemotherapy.
Benzoporphyrin derivative (BPD), synthesized from protoporphyrin and involving the formation of Diels-Alder adducts, contains four components, mono and di-acid derivatives of either ring A or ring B fused porphyrins. These compounds have been isolate