Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elizabeth Wardrop"'
Publikováno v:
Antiviral Research. 68:27-35
Tipranavir is a novel, non-peptidic protease inhibitor, which possesses broad antiviral activity against multiple protease inhibitor-resistant HIV-1. Resistance to this inhibitor however has not yet been well described. HIV was passaged for 9 months
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e615dc6fd45b93c3a9163b8378f8d9fa
https://doi.org/10.1016/j.antiviral.2005.07.003
https://doi.org/10.1016/j.antiviral.2005.07.003
Autor:
George Kukolj, Ivan A. D. Lessard, Mohamed El-Far, Jean-François Fortin, Yoav Peretz, Elizabeth Wardrop, Michael G. Cordingley, Charles Pellerin, Louise Pilote, Richard Bethell, Patrick Salois
Publikováno v:
Journal of Translational Medicine
Background Coexpression of CD160 and PD-1 on HIV-specific CD8+ T-cells defines a highly exhausted T-cell subset. CD160 binds to Herpes Virus Entry Mediator (HVEM) and blocking this interaction with HVEM antibodies reverses T-cell exhaustion. As HVEM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d142de11976c1517729f456803d3505
https://pubmed.ncbi.nlm.nih.gov/25179432
https://pubmed.ncbi.nlm.nih.gov/25179432
Publikováno v:
Biochemistry. 40:1196-1204
The E6 Zn(2+)-binding protein of high-risk human papillomaviruses (HPVs) is one of the major transforming proteins encoded by these tumor viruses. A bacterial system was used to express wild type and truncated forms of HPV-16 E6 linked to GST. The re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc6058a13a5288c480d3497ae7554bbf
https://doi.org/10.1021/bi001837+
https://doi.org/10.1021/bi001837+
Autor:
Anne-Marie Pulichino, Peter W. White, Jacques Archambault, Elizabeth Wardrop, Steve Titolo, Alex Pelletier, Karine Brault, Michael G. Cordingley
Publikováno v:
Journal of Virology. 74:7349-7361
The E1 helicase of papillomavirus is required, in addition to host cell DNA replication factors, during the initiation and elongation phases of viral episome replication. During initiation, the viral E2 protein promotes the assembly of enzymatically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ebcc9e2b4411d7960e785a89b64397
https://doi.org/10.1128/jvi.74.16.7349-7361.2000
https://doi.org/10.1128/jvi.74.16.7349-7361.2000
Autor:
Charles Langelier, Wesley I. Sundquist, Stephen W. Mason, Vaibhav Shah, Nathalie Goudreau, Jean‐François Mercier, Christopher Aiken, Soma S. R. Banik, Steve Titolo, Elizabeth Wardrop, Christopher T. Lemke, Louie Lamorte, Uta K. von Schwedler
Publikováno v:
Antimicrobial agents and chemotherapy, vol 57, iss 10
The identification of novel antiretroviral agents is required to provide alternative treatment options for HIV-1-infected patients. The screening of a phenotypic cell-based viral replication assay led to the identification of a novel class of 4,5-dih
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33301ceb56ae254ca54c379b8bc7ec7b
https://europepmc.org/articles/PMC3811413/
https://europepmc.org/articles/PMC3811413/
Autor:
Faucher Anne-Marie, Jean Rancourt, Christopher T. Lemke, Martin Tremblay, Stephen W. Mason, Christiane Yoakim, Alexandre Gagnon, Jacques Archambault, Lee Fader, Jean‐François Mercier, Steve Titolo, René Coulombe, Uta K. von Schwedler, Soma S. R. Banik, Wesley I. Sundquist, Stephen H. Kawai, Nathalie Goudreau, Bruno Simoneau, Elizabeth Wardrop
The emergence of resistance to existing classes of antiretroviral drugs necessitates finding new HIV-1 targets for drug discovery. The viral capsid (CA) protein represents one such potential new target. CA is sufficient to form mature HIV-1 capsids i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f343645f472c0eb6161d9e8d62b01ad
https://europepmc.org/articles/PMC3393593/
https://europepmc.org/articles/PMC3393593/
Autor:
Daniel Lamarre, Diane Thibeault, G Croteau, Paul C. Anderson, Lise Bourgon, C Clouette, Elizabeth Wardrop, E Cohen, Christiane Yoakim, M Vaillancourt, Christopher Pargellis
Palinavir is a potent inhibitor of the human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) proteases. Replication of laboratory strains (HIV-1, HIV-2, and simian immunodeficiency virus) and HIV-1 clinical isolates is inhibited by palinavir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00b806fc778039437d64f4fbb4e24cb
https://europepmc.org/articles/PMC163834/
https://europepmc.org/articles/PMC163834/
Autor:
Frédéric Sauvé, Jacques Archambault, Karine Brault, Alex Pelletier, Michael G. Cordingley, Anthony A. Amin, Peter W. White, Elizabeth Wardrop, Steve Titolo
Publikováno v:
Scopus-Elsevier
Replication of the genome of human papillomaviruses (HPV) is initiated by the recruitment of the viral E1 helicase to the origin of DNA replication by the viral E2 protein, which binds specifically to the origin. We determined, for HPV type 11 (HPV-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a967e785890964263960508c5ab8b0
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033064136&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033064136&partnerID=MN8TOARS