Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Elizabeth Vafiadaki"'
Autor:
Elizabeth Vafiadaki, Pieter C. Glijnis, Pieter A. Doevendans, Evangelia G. Kranias, Despina Sanoudou
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Arrhythmogenic cardiomyopathy affects significant number of patients worldwide and is characterized by life-threatening ventricular arrhythmias and sudden cardiac death. Mutations in multiple genes with diverse functions have been reported to date in
Externí odkaz:
https://doaj.org/article/7adcb626a9984d7ab0780064f5bcff29
Autor:
Elizabeth Vafiadaki, Kobra Haghighi, Demetrios A. Arvanitis, Evangelia G. Kranias, Despina Sanoudou
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 6947 (2022)
Phospholamban (PLN), a key modulator of Ca2+-homeostasis, inhibits sarcoplasmic reticulum (SR) calcium-ATPase (SERCA2a) and regulates cardiac contractility. The human PLN mutation R14del has been identified in arrhythmogenic cardiomyopathy patients w
Externí odkaz:
https://doaj.org/article/4b8468dab14641dcac6eefa354b7d36b
Autor:
Elizabeth Vafiadaki, Demetrios A. Arvanitis, Aristides G. Eliopoulos, Evangelia G. Kranias, Despina Sanoudou
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9572 (2020)
The cytoskeleton has a primary role in cardiomyocyte function, including the response to mechanical stimuli and injury. The small heat shock protein 20 (Hsp20) conveys protective effects in cardiac muscle that are linked to serine-16 (Ser16) Hsp20 ph
Externí odkaz:
https://doaj.org/article/41c9128779464b16aa1c95323e6e7bb9
Autor:
Demetrios A. Arvanitis, Elizabeth Vafiadaki, Daniel M. Johnson, Evangelia G. Kranias, Despina Sanoudou
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Sudden unexpected cardiac death (SCD) accounts for up to half of all-cause mortality of heart failure patients. Standardized cardiology tools such as electrocardiography, cardiac imaging, electrophysiological and serum biomarkers cannot accurately pr
Externí odkaz:
https://doaj.org/article/7aa8552bd66f47ba8725141bb4d2211e
Autor:
Georgia Kalozoumi, Olga Kel-Margoulis, Elizabeth Vafiadaki, David Greenberg, Hélène Bernard, Hermona Soreq, Antoine Depaulis, Despina Sanoudou
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201742 (2018)
The Mesio-Temporal Lobe Epilepsy syndrome is the most common form of intractable epilepsy. It is characterized by recurrence of focal seizures and is often associated with hippocampal sclerosis and drug resistance. We aimed to characterize the molecu
Externí odkaz:
https://doaj.org/article/4000e85accbf46989401cc9ce88b5a60
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80867 (2013)
In human and experimental heart failure, the activity of the type 1 phosphatase is significantly increased, associated with dephosphorylation of phospholamban, inhibition of the sarco(endo)plasmic reticulum Ca(2+) transport ATPase (SERCA2a) and depre
Externí odkaz:
https://doaj.org/article/5f70732828db494cac6c47bed0b7f41b
Autor:
Malgorzata E, Rogalska, Elizabeth, Vafiadaki, Zoi, Erpapazoglou, Kobra, Haghighi, Lisa, Green, Christos S, Mantzoros, Roger J, Hajjar, Michael, Tranter, Ioannis, Karakikes, Evangelia G, Kranias, Francesca, Stillitano, Panagiota, Kafasla, Despina, Sanoudou
Publikováno v:
Metabolism. 138:155344
Arrhythmogenic cardiomyopathy (ACM) is characterized by life-threatening ventricular arrhythmias and sudden cardiac death and affects hundreds of thousands of patients worldwide. The deletion of Arginine 14 (p.R14del) in the phospholamban (PLN) gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ee103bf77e071c2c8e9a39b2435557
https://doi.org/10.1016/j.metabol.2022.155344
https://doi.org/10.1016/j.metabol.2022.155344
Autor:
Eftaxia-Konstantina Valanti, Katerina Dalakoura-Karagkouni, Panagiotis Fotakis, Elizabeth Vafiadaki, Christos S. Mantzoros, Angeliki Chroni, Vassilis Zannis, Dimitris Kardassis, Despina Sanoudou
Publikováno v:
Metabolism: clinical and experimental. 127
Atherosclerotic Coronary Artery Disease (ASCAD) is the leading cause of mortality worldwide. Novel therapeutic approaches aiming to improve the atheroprotective functions of High Density Lipoprotein (HDL) include the use of reconstituted HDL forms co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d133c293363a63d12db4c9be4d840b1
https://pubmed.ncbi.nlm.nih.gov/34875308
https://pubmed.ncbi.nlm.nih.gov/34875308
Autor:
Aristides G. Eliopoulos, Demetrios A. Arvanitis, Despina Sanoudou, Elizabeth Vafiadaki, Evangelia G. Kranias
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9572, p 9572 (2020)
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9572, p 9572 (2020)
The cytoskeleton has a primary role in cardiomyocyte function, including the response to mechanical stimuli and injury. The small heat shock protein 20 (Hsp20) conveys protective effects in cardiac muscle that are linked to serine-16 (Ser16) Hsp20 ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d345e37a8a27e47109eda7531c0ed195
Autor:
Elizabeth Vafiadaki, George Adly, Hongyan Zhu, Jack Rubinstein, Kobina Essandoh, George Gardner, Qiangrong Liang, Evangelia G. Kranias, Wenfeng Cai, Xiaohong Wang, Chi Keung Lam, Guan-Sheng Liu, Min Jiang, Kobra Haghighi, Despina Sanoudou, Guo-Chang Fan, Persoulla Nicolaou
Publikováno v:
Autophagy. 14:80-97
HSPB6/Hsp20 (heat shock protein family B [small] member 6) has emerged as a novel cardioprotector against stress-induced injury. We identified a human mutant of HSPB6 (HSPB6S10F) exclusively present in dilated cardiomyopathy (DCM) patients. Cardiac e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3546eff57629a5d631f54b202b483af
https://doi.org/10.1080/15548627.2017.1392420
https://doi.org/10.1080/15548627.2017.1392420