Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Elizabeth V Clarke"'
Autor:
Elizabeth V Clarke, Jennifer L Schneider, Frances Lynch, Tia L Kauffman, Michael C Leo, Ana G Rosales, John F Dickerson, Elizabeth Shuster, Benjamin S Wilfond, Katrina A B Goddard
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200139 (2018)
BACKGROUND:Expanded carrier screening can provide risk information for numerous conditions. Understanding how individuals undergoing preconception expanded carrier screening value this information is important. The NextGen study evaluated the use of
Externí odkaz:
https://doaj.org/article/82e7aeb874c1462fa2b72151125f2981
Autor:
Maria I Fonseca, Shuhui Chu, Aimee L Pierce, William D Brubaker, Richard E Hauhart, Diego Mastroeni, Elizabeth V Clarke, Joseph Rogers, John P Atkinson, Andrea J Tenner
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149792 (2016)
Chronic activation of the complement system and induced inflammation are associated with neuropathology in Alzheimer's disease (AD). Recent large genome wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) in the C3b
Externí odkaz:
https://doaj.org/article/e80b68870340438f96ecae3c7cc77d03
Autor:
Marian J. Gilmore, Georgia L. Wiesner, Sapna Syngal, Kristin R. Muessig, Louise S. Acheson, Jennifer L. Schneider, Jennifer E. Cook, Alan F. Rope, Jacob A. Reiss, James V. Davis, Jamilyn M. Zepp, Kellene M. Bergen, Katrina A.B. Goddard, Jessica Ezzell Hunter, Elizabeth Shuster, Tia L. Kauffman, Susan K. Peterson, Elizabeth V. Clarke
Publikováno v:
Fam Cancer
PURPOSE: A subset of colorectal cancer (CRC) cases are attributable to Lynch syndrome (LS), a hereditary form of CRC. Effective evaluation for LS can be done on CRC tumors to guide diagnostic testing. Increased diagnosis of LS allows for surveillance
Autor:
Christa Lese Martin, Noralane M. Lindor, Nara Sobriera, Erin M. Ramos, Jessica Ezzell Hunter, Orit Dagan-Rosenfeld, Katrina A.B. Goddard, Meredith A. Weaver, Kathleen F. Mittendorf, Marc S. Williams, Kristy Lee, Kristin R. Muessig, Aleksandar Milosavljevic, Ronak Y. Patel, Anne Slavotinek, Shannon Rego, Elizabeth M. Webber, James P. Evans, Leslie G. Biesecker, Julianne M. O’Daniel, Erin Currey, Elizabeth V. Clarke, Adam H. Buchanan
The use of genome-scale sequencing allows for identification of genetic findings beyond the original indication for testing (secondary findings). The ClinGen Actionability Working Group’s (AWG) protocol for evidence synthesis and semi-quantitative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991984b84ff9a2357404bb3b659abf10
https://europepmc.org/articles/PMC6211797/
https://europepmc.org/articles/PMC6211797/
Autor:
Stephanie A. Kraft, C. Sue Richards, John F. Dickerson, Tia L. Kauffman, Carmit K. McMullen, Benjamin S. Wilfond, Alan F. Rope, Gail P. Jarvik, Kevin Lutz, Elizabeth V. Clarke, Patricia Himes, Marian J. Gilmore, Michael C. Leo, Kathryn M. Porter, Sumit Punj, Frances L. Lynch, Jacob A. Reiss, Katrina A.B. Goddard, Jennifer L. Schneider
Publikováno v:
Health Aff (Millwood)
Genomics-based carrier screening is one of many opportunities to use genomic information to inform medical decision making, but clinicians, health care delivery systems, and payers need to determine whether to offer screening and how to do so in an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eeb29b68fb1c591377a3bbf05e0a539
https://europepmc.org/articles/PMC10320860/
https://europepmc.org/articles/PMC10320860/
Autor:
Ana G. Rosales, Elizabeth V. Clarke, Katrina A.B. Goddard, Jennifer L. Schneider, Frances L. Lynch, Tia L. Kauffman, Michael C. Leo, Elizabeth Shuster, John F. Dickerson, Benjamin S. Wilfond
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200139 (2018)
PLoS ONE
PLoS ONE
Background Expanded carrier screening can provide risk information for numerous conditions. Understanding how individuals undergoing preconception expanded carrier screening value this information is important. The NextGen study evaluated the use of
Autor:
Elizabeth V. Clarke, Andrea J. Tenner
Publikováno v:
Journal of Leukocyte Biology. 96:745-756
The complement system is an ancient and critical effector mechanism of the innate immune system as it senses, kills, and clears infectious and/or dangerous particles and alerts the immune system to the presence of the infection and/or danger. Interes
Autor:
Frances Y. McWhorter, Elizabeth V. Clarke, Norikiyo Ueno, Katherine S. Harker, Melissa B. Lodoen, Wendy Liu, Andrea J. Tenner
Publikováno v:
Cellular Microbiology. 16:580-595
Peripheral blood monocytes are actively infected by Toxoplasma gondii and can function as 'Trojan horses' for parasite spread in the bloodstream. Using dynamic live-cell imaging, we visualized the transendothelial migration (TEM) of T. gondii-infecte
Publikováno v:
Bio-protocol, vol 3, iss 17
To characterize macrophage gene expression profiles during the uptake of autologous apoptotic cells, we developed a unique, more physiologic system using primary human monocyte derived macrophages purified via a nonactivating isolation procedure (and
Autor:
John P. Atkinson, Diego Mastroeni, Andrea J. Tenner, Maria I. Fonseca, Joseph Rogers, Richard E. Hauhart, Aimee Pierce, Shu-Hui Chu, William D. Brubaker, Elizabeth V. Clarke
Publikováno v:
Fonseca, MI; Chu, S; Pierce, AL; Brubaker, WD; Hauhart, RE; Mastroeni, D; et al.(2016). Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function. PLOS ONE, 11(2). doi: 10.1371/journal.pone.0149792. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/532355p9
PloS one, vol 11, iss 2
PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0149792 (2016)
PloS one, vol 11, iss 2
PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0149792 (2016)
Chronic activation of the complement system and induced inflammation are associated with neuropathology in Alzheimer's disease (AD). Recent large genome wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) in the C3b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225649cd6dbeac70bc9fe61cb1f3aedf
http://www.escholarship.org/uc/item/532355p9
http://www.escholarship.org/uc/item/532355p9