Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Elizabeth V, Lawler"'
Autor:
Tianyu Li, Nan Lin, Elizabeth V. Lawler, Julieta Leone, Eric P. Winer, Sara M. Tolaney, Luke Walker, O. Metzger Filho, Rachel A. Freedman, Jerry Younger, William T. Barry, Lorenzo Trippa, Zhenying Tan-Wasielewski, Ian E. Krop
Publikováno v:
Annals of Oncology. 31:1231-1239
Background Brain metastases are frequent in HER2-positive breast cancer. ONT-380 (tucatinib) is a potent selective inhibitor of HER2 with intracranial activity in preclinical models. Patients and methods This was a phase I study of tucatinib with tra
Autor:
Kelly Cho, David R. Gagnon, Jane A. Driver, Arman Altincatal, Nicole Kosik, Stephan Lanes, Elizabeth V. Lawler
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2014 (2014)
Growing evidence suggests that Alzheimer’s disease and other types of dementia are underdiagnosed and poorly documented. In our study, we describe patterns of dementia coding and treatment in the Veteran’s Administration New England Healthcare Sy
Externí odkaz:
https://doaj.org/article/fbfb02df1d5f4a7dbd0061cae0fbca5c
Autor:
Luke Walker, Ian E. Krop, Sara M. Tolaney, Rachel A. Freedman, Hao Guo, William H. Barry, EP Winer, Elizabeth V. Lawler, Jerry Younger, Otto Metzger, Nu Lin
Publikováno v:
Cancer Research. 77:P1-12
Background: Brain metastases remain an important cause of death for pts with advanced HER2+ BC. ONT-380 is an oral, potent and selective inhibitor of HER2 capable of penetrating the blood brain barrier in pre-clinical models. We evaluated the safety
Autor:
Jiani Hu, Sara M. Tolaney, Dan G. Duda, Jose Pablo Leone, Rakesh K. Jain, Eric P. Winer, Nan Lin, Elizabeth V. Lawler, Sally Tan, William T. Barry, Lorenzo Trippa, Elizabeth R. Gerstner
Publikováno v:
Breast cancer research and treatment. 179(1)
To analyze the efficacy and tolerability of cabozantinib—a small molecule inhibitor of MET and VEGFR2—alone or with trastuzumab in patients with breast cancer brain metastases (BCBM). This single-arm phase II study enrolled patients with new or p
Autor:
Shannon Puhalla, Kimberly L. Blackwell, Eric P. Winer, Alarice C. Lowe, Roisin M. Connolly, Kenneth R. Hess, N. Ryabin, Nathalie Y. R. Agar, Jeffrey S. Wefel, Christina I. Herold, Nan Lin, Sarah Farooq, Polly A. Niravath, Mothaffar F. Rimawi, Elizabeth V. Lawler, Ian E. Krop, Nuhad K. Ibrahim, Rachel A. Freedman, Catherine Van Poznak, Minetta C. Liu, Beverly Moy, Michelle E. Melisko, Antonio C. Wolff, Rebecca Gelman
Publikováno v:
Journal of Clinical Oncology. 34:945-952
Purpose Evidence-based treatments for metastatic, human epidermal growth factor receptor 2 (HER2)–positive breast cancer in the CNS are limited. Neratinib is an irreversible inhibitor of erbB1, HER2, and erbB4, with promising activity in HER2-posit
Autor:
Tari A. King, Kandice K. Ludwig, Elizabeth V. Lawler, Shawna C. Willey, Clifford A. Hudis, Rebecca Gelman, Faina Nakhlis, J. Dirk Iglehart, E. Shelley Hwang, Lauren Gilmore, Stuart J. Schnitt, N. Ryabin, Isabelle Bedrosian, Mehra Golshan
Publikováno v:
Annals of Surgical Oncology. 23:722-728
Lobular neoplasia (LN) represents a spectrum of atypical proliferative lesions, including atypical lobular hyperplasia and lobular carcinoma-in-situ. The need for excision for LN found on core biopsy (CB) is controversial. We conducted a prospective
Autor:
David R. Gagnon, Subha Chittamooru, Elizabeth V. Lawler, Jennifer R. Fonda, Edward P. Monnelly
Publikováno v:
Journal of Clinical Psychopharmacology. 35:57-62
OBJECTIVE Continuous antipsychotic treatment is important in schizophrenia, and studies have shown that rates of discontinuation are high. Some studies suggest that weight gain may lead schizophrenic patients to discontinue treatment, whereas other s
Publikováno v:
Circulation: Cardiovascular Interventions. 5:372-380
Background— Current guidelines recommend combining clopidogrel with aspirin for up to 1 year after coronary stenting, but the value of clopidogrel beyond this time is uncertain. Methods and Results— We evaluated all patients in the Veterans Admin
Publikováno v:
Journal of the American Geriatrics Society. 60:910-915
Objectives: To examine the specificity of dementia coding in large populations. Design: Retrospective cohort and chart review study of dementia diagnosis. Setting: U.S. Department of Veterans Affairs (VA) New England healthcare system. Participants:
Autor:
Alisa K. Lincoln, Matthew C. Miller, Jaimie L. Gradus, Henrik Toft Sørensen, Ping Qin, Elizabeth V. Lawler, Timothy L. Lash
Publikováno v:
Gradus, J L, Qin, P, Lincoln, A K, Miller, M, Lawler, E, Sørensen, H T & Lash, T L 2012, ' Sexual victimization and completed suicide among Danish female adults ', Violence Against Women, vol. 18, no. 5, pp. 552-61 . https://doi.org/10.1177/1077801212453141
Although sexual victimization has been associated with suicidal behaviors, its association with completed suicide has not been examined. We investigated this association among Danish women using longitudinal data and a conservative definition of vict