Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Elizabeth Skippington"'
Autor:
Eric M. Kofoed, Ignacio Aliagas, Terry Crawford, Jialin Mao, Seth F. Harris, Min Xu, Shumei Wang, Ping Wu, Fang Ma, Kevin Clark, Jessica Sims, Yiming Xu, Yutian Peng, Elizabeth Skippington, Ying Yang, Janina Reeder, Savita Ubhayakar, Matt Baumgardner, Zhengyin Yan, Jacob Chen, Summer Park, Hua Zhang, Chun-Wan Yen, Maria Lorenzo, Nicholas Skelton, Xiaorong Liang, Liuxi Chen, Bridget Hoag, Chun Sing Li, Zhiguo Liu, John Wai, Xingrong Liu, Jun Liang, Man Wah Tan
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Guanine nucleotides are required for growth and viability of cells due to their structural role in DNA and RNA, and their regulatory roles in translation, signal transduction, and cell division. The natural antibiotic mycophenolic acid (MPA)
Externí odkaz:
https://doaj.org/article/92da914a1cc64fff8b2ab55b0e41acbf
Autor:
Jordan S. Mar, Naruhisa Ota, Nick D. Pokorzynski, Yutian Peng, Allan Jaochico, Dewakar Sangaraju, Elizabeth Skippington, Annemarie N. Lekkerkerker, Michael E. Rothenberg, Man-Wah Tan, Tangsheng Yi, Mary E. Keir
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Background IL-22 is induced by aryl hydrocarbon receptor (AhR) signaling and plays a critical role in gastrointestinal barrier function through effects on antimicrobial protein production, mucus secretion, and epithelial cell differentiation
Externí odkaz:
https://doaj.org/article/07f3567e2214401ab5134a8634835824
Autor:
Homer Pantua, Elizabeth Skippington, Marie-Gabrielle Braun, Cameron L. Noland, Jingyu Diao, Yutian Peng, Susan L. Gloor, Donghong Yan, Jing Kang, Anand Kumar Katakam, Janina Reeder, Georgette M. Castanedo, Keira Garland, Laszlo Komuves, Meredith Sagolla, Cary D. Austin, Jeremy Murray, Yiming Xu, Zora Modrusan, Min Xu, Emily J. Hanan, Sharookh B. Kapadia
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Clinical development of antibiotics with novel mechanisms of action to kill pathogenic bacteria is challenging, in part, due to the inevitable emergence of resistance. A phenomenon of potential clinical importance that is broadly overlooked
Externí odkaz:
https://doaj.org/article/ad7dc0127d394ca78d233d455e860331
Publikováno v:
Microbial Cell, Vol 4, Iss 4, Pp 108-111 (2017)
Secretion of proteins into the extracellular environment is crucial for the normal physiology and virulence of pathogenic bacteria. Type I signal peptidase (SPase I) mediates the final step of bacterial secretion, by cleaving proteins at their signal
Externí odkaz:
https://doaj.org/article/84dde039ea594003a7f4b6e146ce82cf
Autor:
Ning Chai, Lee R. Swem, Summer Park, Gerald Nakamura, Nancy Chiang, Alberto Estevez, Rina Fong, Lynn Kamen, Elviza Kho, Mike Reichelt, Zhonghua Lin, Henry Chiu, Elizabeth Skippington, Zora Modrusan, Jeremy Stinson, Min Xu, Patrick Lupardus, Claudio Ciferri, Man-Wah Tan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Influenza B virus (IBV) co-circulates with influenza A virus to cause annual epidemics. Here, Chaiet al. isolate a human monoclonal antibody that binds to a conserved epitope in the viral HA protein, neutralizes IBV strains in vitro, and protects mic
Externí odkaz:
https://doaj.org/article/d697ead9ca194b4d8f53f1f10eadf047
Autor:
Ning Chai, Lee R. Swem, Summer Park, Gerald Nakamura, Nancy Chiang, Alberto Estevez, Rina Fong, Lynn Kamen, Elviza Kho, Mike Reichelt, Zhonghua Lin, Henry Chiu, Elizabeth Skippington, Zora Modrusan, Jeremy Stinson, Min Xu, Patrick Lupardus, Claudio Ciferri, Man-Wah Tan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-2 (2017)
Nature Communications 8: Article number: 14234 (2017); Published: 19 January 2017; Updated: 25 May 2017 This Article contains errors in Fig. 5c. The blue squares should be labelled ‘Water+46B8’ and the green triangles should be labelled ‘Tamifl
Externí odkaz:
https://doaj.org/article/fd4f9823a247424798f021121a6f98cd
Autor:
Elizabeth Skippington, Mark A. Ragan
Publikováno v:
Open Biology, Vol 2, Iss 9 (2012)
Genetic material can be transmitted not only vertically from parent to offspring, but also laterally (horizontally) from one bacterial lineage to another. Lateral genetic transfer is non-uniform; biases in its nature or frequency construct communitie
Externí odkaz:
https://doaj.org/article/cc1d37f5e3b64f99b400f40b963023cf
Autor:
Ke-Jung Huang, Homer Pantua, Jingyu Diao, Elizabeth Skippington, Michael Volny, Wendy Sandoval, Varnesh Tiku, Yutian Peng, Meredith Sagolla, Donghong Yan, Jing Kang, Anand Kumar Katakam, Nairie Michaelian, Mike Reichelt, Man-Wah Tan, Cary D. Austin, Min Xu, Emily Hanan, Sharookh B. Kapadia
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Acinetobacter baumannii is a clinically important, predominantly health care–associated gram-negative bacterium with high rates of emerging resistance worldwide. Given the urgent need for novel antibacterial therapies against A. baumannii , we focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d0dc82e096281ab4df29647d2a70859
https://doi.org/10.1073/pnas.2123117119
https://doi.org/10.1073/pnas.2123117119
Autor:
Anh Miu, Benjamin D. Sellers, Maria Ruiz-Gonzalez, Jian Payandeh, Peter Liu, L. Martin, Kerry R Buchholz, Dewakar Sangaraju, Guanghui Han, Mark S. Hunter, Elizabeth Skippington, Wendy Sandoval, Emily J. Hanan, Cameron L. Noland, Trisha Dela Vega, Daniel P. DePonte, Erik Verschueren, Danielle L. Swem, Min Xu, Sheerin K. Shahidi-Latham, Nicholas N. Nickerson, Summer Park, Steven T. Rutherford, Nicholas J. Skelton, Qingling Li, Janina Reeder, Kelly M. Storek, Cornelius Gati, Thomas Clairfeuille
Publikováno v:
Nature. 584:479-483
Lipopolysaccharide (LPS) resides in the outer membrane of Gram-negative bacteria where it is responsible for barrier function1,2. LPS can cause death as a result of septic shock, and its lipid A core is the target of polymyxin antibiotics3,4. Despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60f6821b117c57797c53d6a1fae98ab
https://doi.org/10.1038/s41586-020-2597-x
https://doi.org/10.1038/s41586-020-2597-x
Autor:
Eric M. Kofoed, Russell E. Vance, Man-Wah Tan, Tommy K. Cheung, Yuxin Liang, Giovanni Luchetti, Christopher M. Rose, Justin L. Roncaioli, Elizabeth Skippington, Kim Newton, Janina Reeder, Vishva M. Dixit, Alexander F. Schubert, Rohit Reja, Benjamin Haley, Nobuhiko Kayagaki, Roberto A. Chavez, Isabelle Lehoux, Joshua D. Webster
Publikováno v:
Cell Host Microbe
Summary The pore-forming protein gasdermin D (GSDMD) executes lytic cell death called pyroptosis to eliminate the replicative niche of intracellular pathogens. Evolution favors pathogens that circumvent this host defense mechanism. Here, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35137471dfdcf537a68417e65484c59f
https://europepmc.org/articles/PMC9122893/
https://europepmc.org/articles/PMC9122893/
