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of 7
pro vyhledávání: '"Elizabeth Scisci"'
Autor:
Ahmed R El-Awady, Brodie Miles, Elizabeth Scisci, Zoya B Kurago, Chithra D Palani, Roger M Arce, Jennifer L Waller, Caroline A Genco, Connie Slocum, Matthew Manning, Patricia V Schoenlein, Christopher W Cutler
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1004647 (2015)
Signaling via pattern recognition receptors (PRRs) expressed on professional antigen presenting cells, such as dendritic cells (DCs), is crucial to the fate of engulfed microbes. Among the many PRRs expressed by DCs are Toll-like receptors (TLRs) and
Externí odkaz:
https://doaj.org/article/8c26c24211924711b92b30d02e63acb4
Autor:
Brodie Miles, Julio A. Carrion, John C. O'Neill, Aaron Rawlings, Elizabeth Scisci, J. Kobi Stern, Ibrahim Zakhary, Christopher W. Cutler, Cristiano Susin, Ahmed El-Awady
Publikováno v:
Infection and Immunity. 82:101-111
Several intracellular pathogens, including a key etiological agent of chronic periodontitis, Porphyromonas gingivalis , infect blood myeloid dendritic cells (mDCs). This infection results in pathogen dissemination to distant inflammatory sites (i.e.,
Autor:
Caroline A. Genco, Julio A. Carrion, Christopher W. Cutler, Gregory J. Sabino, Brodie Miles, Elizabeth Scisci
Publikováno v:
Journal of Leukocyte Biology. 94:281-289
Maintenance of blood DC homeostasis is essential to preventing autoimmunity while controlling chronic infection. However, the ability of bacteremic pathogens to directly regulate blood DC homeostasis has not been defined. One such bacteremic pathogen
Autor:
William D. McCaig, Amir E. Zeituni, David G. Thanassi, Elizabeth Scisci, Christopher W. Cutler
Publikováno v:
Journal of Bacteriology. 192:4103-4110
We recently reported that the oral mucosal pathogen Porphyromonas gingivalis , through its 67-kDa Mfa1 (minor) fimbria, targets the C-type lectin receptor DC-SIGN for invasion and persistence within human monocyte-derived dendritic cells (DCs). The D
Autor:
Caroline A. Genco, Patricia V. Schoenlein, Brodie Miles, Christopher W. Cutler, Roger M. Arce, Ahmed El-Awady, Jennifer L. Waller, Chithra D. Palani, Elizabeth Scisci, Matthew Manning, Zoya B. Kurago, Connie Slocum
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 10, Iss 2, p e1004647 (2015)
PLoS Pathogens, Vol 10, Iss 2, p e1004647 (2015)
Signaling via pattern recognition receptors (PRRs) expressed on professional antigen presenting cells, such as dendritic cells (DCs), is crucial to the fate of engulfed microbes. Among the many PRRs expressed by DCs are Toll-like receptors (TLRs) and
Autor:
Adam Bear, Elizabeth Scisci, Julio A. Carrion, Gregory J. Sabino, Ying Gu, Brodie Miles, Caroline A. Genco, David L. Brown, Amir E. Zeituni, Christopher W. Cutler
The low-grade oral infection chronic periodontitis (CP) has been implicated in coronary artery disease risk, but the mechanisms are unclear. In this study, a pathophysiological role for blood dendritic cells (DCs) in systemic dissemination of oral mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46b499df88138a628af2b615043abde
https://europepmc.org/articles/PMC3459682/
https://europepmc.org/articles/PMC3459682/
Publikováno v:
The Journal of Immunology. 184:42.7-42.7
We recently reported that the oral mucosal pathogen Porphyromonas gingivalis targets the C- type lectin receptor DC-SIGN for invasion and persistence within human monocyte-derived dendritic cells (DCs). The DCs respond by inducing an immunosuppressiv