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pro vyhledávání: '"Elizabeth S. Jaensch"'
Autor:
Manashree Damle, Jesse C. Cochrane, Robert E. Kingston, Ethan Z. McCaslin, Sharon K. Marr, Theresa A. Oei, Elizabeth S. Jaensch, Jinjin Zhu
Publikováno v:
Mol Cell
The CBX family of proteins is central to proper mammalian development via key roles in Polycomb-mediated maintenance of repression. CBX proteins in differentiated lineages have chromatin compaction and phase separation activities that might contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90a61116f0cf2b6a6a8c2c92b20c804
https://europepmc.org/articles/PMC8966356/
https://europepmc.org/articles/PMC8966356/
Publikováno v:
Genes & Development. 31:1069-1072
Development requires the expression of master regulatory genes necessary to specify a cell lineage. Equally significant is the stable and heritable silencing of master regulators that would specify alternative lineages. This regulated gene silencing
Autor:
Alan B. Cantor, Jian Xu, Elizabeth S. Jaensch, Alireza Ghamari, Thomas E. Akie, Stuart H. Orkin, Daniel E. Bauer, Richard Giadone
Publikováno v:
Blood. 124:245-245
The GATA family transcription factors GATA2 and GATA1 play reciprocal roles during terminal erythroid and megakaryocytic maturation. GATA2 is expressed early in hematopoiesis and is required for early progenitor cell proliferation and survival. It mu