Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Elizabeth S Waters"'
Autor:
Julie H. Jeon, Erin E. Kaiser, Elizabeth S. Waters, Xueyuan Yang, Jeferson M. Lourenco, Madison M. Fagan, Kelly M. Scheulin, Sydney E. Sneed, Soo K. Shin, Holly A. Kinder, Anil Kumar, Simon R. Platt, Jeongyoun Ahn, Kylee J. Duberstein, Michael J. Rothrock, Todd R. Callaway, Jin Xie, Franklin D. West, Hea Jin Park
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Impaired gut homeostasis is associated with stroke often presenting with leaky gut syndrome and increased gut, brain, and systemic inflammation that further exacerbates brain damage. We previously reported that intracisternal administration
Externí odkaz:
https://doaj.org/article/6d469ec2e68b470295666853b023f23d
Autor:
Elizabeth S. Waters, Erin E. Kaiser, Xueyuan Yang, Madison M. Fagan, Kelly M. Scheulin, Julie H. Jeon, Soo K. Shin, Holly A. Kinder, Anil Kumar, Simon R. Platt, Kylee J. Duberstein, Hea Jin Park, Jin Xie, Franklin D. West
Publikováno v:
IBRO Neuroscience Reports, Vol 10, Iss , Pp 18-30 (2021)
Background: The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments with significant limitations available to patients. Tanshinone IIA (Tan IIA) is a
Externí odkaz:
https://doaj.org/article/d28f059093814129a866cebfb77646c7
Autor:
Kelly M. Scheulin, Brian J. Jurgielewicz, Samantha E. Spellicy, Elizabeth S. Waters, Emily W. Baker, Holly A. Kinder, Gregory A. Simchick, Sydney E. Sneed, Janet A. Grimes, Qun Zhao, Steven L. Stice, Franklin D. West
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Harnessing the maximum diagnostic potential of magnetic resonance imaging (MRI) by including stroke lesion location in relation to specific structures that are associated with particular functions will likely increase the potential to predic
Externí odkaz:
https://doaj.org/article/6680f945ead74649a55304ae1530c1db
Autor:
Sydney E. Sneed, Kelly M. Scheulin, Erin E. Kaiser, Madison M. Fagan, Brian J. Jurgielewicz, Elizabeth S. Waters, Samantha E. Spellicy, Kylee J. Duberstein, Simon R. Platt, Emily W. Baker, Steven L. Stice, Holly A. Kinder, Franklin D. West
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
The Stroke Therapy Academic Industry Roundtable (STAIR) has recommended that novel therapeutics be tested in a large animal model with similar anatomy and physiology to humans. The pig is an attractive model due to similarities in brain size, organiz
Externí odkaz:
https://doaj.org/article/33722d55cfbf4dc5af73b07d776604a2
Autor:
Samantha E. Spellicy, Kelly M. Scheulin, Emily W. Baker, Brian J. Jurgielewicz, Holly A. Kinder, Elizabeth S. Waters, Janet A. Grimes, Steven L. Stice, Franklin D. West
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2021)
Histopathological analysis of cellular changes in the stroked brain provides critical information pertaining to inflammation, cell death, glial scarring, and other dynamic injury and recovery responses. However, commonly used manual approaches are hi
Externí odkaz:
https://doaj.org/article/96037dfd79ff4c51b8411fdfa55c43ed
Autor:
Julie Jeon, Jeferson Lourenco, Erin E. Kaiser, Elizabeth S. Waters, Kelly M. Scheulin, Xi Fang, Holly A. Kinder, Simon R. Platt, Michael J. Rothrock, Todd R. Callaway, Franklin D. West, Hea Jin Park
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Stroke is a major cause of death and long-term disability affecting seven million adults in the United States each year. Recently, it has been demonstrated that neurological diseases, associated pathology, and susceptibility changes correlated with c
Externí odkaz:
https://doaj.org/article/e736de15437f4134a7ba7b9e7d32cd40
Autor:
Sydney E Sneed, Gregory Simchick, Emily W Baker, Brian J. Jurgielewicz, Qun Zhao, Kelly M. Scheulin, Elizabeth S. Waters, Janet A. Grimes, Samantha E. Spellicy, Holly A. Kinder, Steven L. Stice, Franklin D. West
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Harnessing the maximum diagnostic potential of magnetic resonance imaging (MRI) by including stroke lesion location in relation to specific structures that are associated with particular functions will likely increase the potential to predict functio
Autor:
Xueyuan Yang, Soo K. Shin, Jin Xie, Kylee J. Duberstein, Madison M. Fagan, Simon R. Platt, Kelly M. Scheulin, Erin E. Kaiser, Holly A. Kinder, Elizabeth S. Waters, Julie Jeon, Franklin D. West, Anil Kumar, Hea Jin Park
Publikováno v:
IBRO Neuroscience Reports
IBRO Neuroscience Reports, Vol 10, Iss, Pp 18-30 (2021)
IBRO Neuroscience Reports, Vol 10, Iss, Pp 18-30 (2021)
Background The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments with significant limitations available to patients. Tanshinone IIA (Tan IIA) is a p
Autor:
Erin E Kaiser, Elizabeth S Waters, Xueyuan Yang, Madison M Fagan, Kelly M Scheulin, Sydney E Sneed, Savannah R Cheek, Julie Heejin Jeon, Soo K Shin, Holly A Kinder, Anil Kumar, Simon R Platt, Kylee J Duberstein, Hea Jin Park, Jin Xie, Franklin D West
Publikováno v:
Stem cells translational medicine. 11(10)
Induced pluripotent stem cell-derived neural stem cells (iNSCs) are a multimodal stroke therapeutic that possess neuroprotective, regenerative, and cell replacement capabilities post-ischemia. However, long-term engraftment and efficacy of iNSCs is l
Autor:
Erin E Kaiser, Elizabeth S Waters, Xueyuan Yang, Madison M Fagan, Kelly M Scheulin, Sydney E Sneed, Julie H Jeon, Soo K Shin, Holly A Kinder, Anil Kumar, Simon R Platt, Kylee J Duberstein, Hea Jin Park, Jin Xie, Franklin D West
Publikováno v:
Stroke. 53
Induced pluripotent stem cell-derived neural stem cells (iNSCs) have led to cellular and functional recovery in ischemic stroke models. However, the therapeutic effects of iNSC treatment are limited by decreased cell survival in the cytotoxic stroke