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pro vyhledávání: '"Elizabeth S Fuller"'
Autor:
Brenda Faiola, Jason Rose, Diane J. Abernethy, Linda J. Pluta, Leslie Recio, Victoria A. Wong, Elizabeth S Fuller
Publikováno v:
STEM CELLS. 22:750-758
Chronic exposure to benzene results in progressive decline of hematopoietic function and may lead to the onset of various disorders, including aplastic anemia, myelodysplastic syndrome, and leukemia. Damage to macromolecules resulting from benzene me
Autor:
Brenda Faiola, Diane J. Abernethy, Leslie Recio, James B. Mangum, Alison K. Bauer, Elizabeth S Fuller, Victoria A. Wong, Linda J. Pluta, Jeffrey I. Everitt
Publikováno v:
Toxicological Sciences. 75:321-332
Benzene, a carcinogen that induces chromosomal breaks, is strongly associated with leukemias in humans. Possible genetic determinants of benzene susceptibility include proteins involved in repair of benzene-induced DNA damage. The catalytic subunit o
Publikováno v:
Mutation research. 549(1-2)
Acute myeloid leukemia and chronic lymphocytic leukemia are associated with benzene exposure. In mice, benzene induces chromosomal breaks as a primary mode of genotoxicity in the bone marrow (BM). Benzene-induced DNA lesions can lead to changes in he