Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Elizabeth Rendina"'
Autor:
Ananya Nandy, Ron C. M. Helderman, Santosh Thapa, Shobana Jayapalan, Alison Richards, Nikita Narayani, Michael P. Czech, Clifford J. Rosen, Elizabeth Rendina-Ruedy
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract Bone formation is a highly energy-demanding process that can be impacted by metabolic disorders. Glucose has been considered the principal substrate for osteoblasts, although fatty acids are also important for osteoblast function. Here, we r
Externí odkaz:
https://doaj.org/article/179b81dbcab6470588c6576fdde2ce17
Autor:
Nathalie S. Alekos, Priyanka Kushwaha, Soohyun P. Kim, Zhu Li, Abdullah Abood, Naomi Dirckx, Susan Aja, Joe Kodama, Jean G. Garcia-Diaz, Satoru Otsuru, Elizabeth Rendina-Ruedy, Michael J. Wolfgang, Ryan C. Riddle
Publikováno v:
JCI Insight, Vol 8, Iss 6 (2023)
The energetic costs of bone formation require osteoblasts to coordinate their activities with tissues, like adipose, that can supply energy-dense macronutrients. In the case of intermittent parathyroid hormone (PTH) treatment, a strategy used to redu
Externí odkaz:
https://doaj.org/article/38d6eb0c21c345fa8d965c20ac0c94e1
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Osteoporosis is a common endocrinologic disorder characterized as a chronic bone loss condition. Sexual dimorphism is ubiquitous in the incidence of osteoporosis with post-menopausal women being acutely affected. Gonadal sex hormones including estrog
Externí odkaz:
https://doaj.org/article/dcdb57ca28144998b67783303576bf2c
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Bone is a highly dynamic tissue that undergoes continuous remodeling by bone resorbing osteoclasts and bone forming osteoblasts, a process regulated in large part by osteocytes. Dysregulation of these coupled catabolic and anabolic processes as in th
Externí odkaz:
https://doaj.org/article/31c2350f50bc4e47ad10eb575ca8c72b
Publikováno v:
Molecular Metabolism, Vol 60, Iss , Pp 101480- (2022)
Background: Late in the nineteenth century, it was theorized that a circulating product produced by the parathyroid glands could negatively impact skeletal homeostasis. A century later, intermittent administration of that protein, namely parathyroid
Externí odkaz:
https://doaj.org/article/f0cc1481f3cd4d0cbdde9a638dc0e6ea
Publikováno v:
Metabolites, Vol 13, Iss 4, p 578 (2023)
Bone is a dynamic tissue composed of cells, an extracellular matrix, and mineralized portion. Osteoblasts are responsible for proper bone formation and remodeling, and function. These processes are endergonic and require cellular energy in the form o
Externí odkaz:
https://doaj.org/article/09973f2f2b944c02a009d9f4ab1da9cb
Autor:
Jennifer L. Graef, Ping Ouyang, Yan Wang, Elizabeth Rendina-Ruedy, Megan R. Lerner, Denver Marlow, Edralin A. Lucas, Brenda J. Smith
Publikováno v:
Journal of Functional Foods, Vol 42, Iss , Pp 262-270 (2018)
Dried plum has unique anabolic effects on bone, but the responsible bioactive components have remained unclear. This study investigated components of dried plum with potential osteoprotective activity utilizing aged, osteopenic Sprague Dawley rats fe
Externí odkaz:
https://doaj.org/article/96ab7cfac85d4534a8797deae30523da
Autor:
Elizabeth Rendina-Ruedy, Kelsey D. Hembree, Angela Sasaki, McKale R. Davis, Stan A. Lightfoot, Stephen L. Clarke, Edralin A. Lucas, Brenda J. Smith
Publikováno v:
Journal of Nutrition and Metabolism, Vol 2015 (2015)
Type 2 diabetes mellitus (T2DM) represents a complex clinical scenario of altered energy metabolism and increased fracture incidence. The C57BL/6 mouse model of diet-induced obesity has been used to study the mechanisms by which altered glucose homeo
Externí odkaz:
https://doaj.org/article/d480beed32f84f32813fcb4b32624a4f
Autor:
Elizabeth Rendina, Kelsey D Hembree, McKale R Davis, Denver Marlow, Stephen L Clarke, Bernard P Halloran, Edralin A Lucas, Brenda J Smith
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60569 (2013)
Interest in dried plum has increased over the past decade due to its promise in restoring bone and preventing bone loss in animal models of osteoporosis. This study compared the effects of dried plum on bone to other dried fruits and further explored
Externí odkaz:
https://doaj.org/article/dc6c0d92c475413f9d2081bb8357806f
Autor:
Elizabeth M Hennen, Mingfang Ao, Nestor de la Visitacion, Wei Chen, Sasidhar Uppuganti, Elizabeth Rendina-Ruedy, Jeffry Nyman, David G Harrison
Publikováno v:
Hypertension. 79
Autoimmune and inflammatory diseases such as obesity and cancer are highly linked to altered bone growth and osteoporosis. Hypertension (HTN) is an inflammatory condition associated with reduced bone mineral density and increased risk for fragility f