Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Elizabeth R. Wright"'
Autor:
Bryan S. Sibert, Joseph Y. Kim, Jie E. Yang, Zunlong Ke, Christopher C. Stobart, Martin L. Moore, Elizabeth R. Wright
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Respiratory syncytial virus (RSV) is an enveloped, filamentous, negative-strand RNA virus that causes significant respiratory illness worldwide. RSV vaccines are available, however there is still significant need for research to support the
Externí odkaz:
https://doaj.org/article/a4975808b5ea4bf8bd368888c3c57cbe
Autor:
Peter J. Halfmann, Kathryn Loeffler, Augustine Duffy, Makoto Kuroda, Jie E. Yang, Elizabeth R. Wright, Yoshihiro Kawaoka, Ravi S. Kane
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The 2002 SARS outbreak, the 2019 emergence of COVID-19, and the continuing evolution of immune-evading SARS-CoV-2 variants together highlight the need for a broadly protective vaccine against ACE2-utilizing sarbecoviruses. While updated vari
Externí odkaz:
https://doaj.org/article/65296e863059488f805a3afd0540a6c6
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1006 (2024)
Bacterial cytoplasmic organelles are diverse and serve many varied purposes. Here, we employed Rhodobacter sphaeroides to investigate the accumulation of carbon and inorganic phosphate in the storage organelles, polyhydroxybutyrate (PHB) and polyphos
Externí odkaz:
https://doaj.org/article/7ef59829f86940328a0b5b2517eda5c6
Autor:
Leticia Beltrán, Holly Torsilieri, Jonasz B. Patkowski, Jie E. Yang, James Casanova, Tiago R. D. Costa, Elizabeth R. Wright, Edward H. Egelman
Publikováno v:
mBio, Vol 15, Iss 1 (2024)
ABSTRACTBacterial conjugation, a process of horizontal gene transfer, plays a key role in promoting the spread of antimicrobial resistance among human pathogens. The mechanism of conjugation involves the development of a conjugative pilus that forms
Externí odkaz:
https://doaj.org/article/dfd06a30b5de4601a4a96aec04185cba
Autor:
Bryan D. Lakey, François Alberge, Daniel Parrell, Elizabeth R. Wright, Daniel R. Noguera, Timothy J. Donohue
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Cell elongation and division are essential aspects of the bacterial life cycle that must be coordinated for viability and replication. The impact of misregulation of these processes is not well understood as these systems are often not amena
Externí odkaz:
https://doaj.org/article/a0bc4e4db6de4073adc379a5c7bd7d29
Autor:
Peter J. Halfmann, Steven J. Frey, Kathryn Loeffler, Makoto Kuroda, Tadashi Maemura, Tammy Armbrust, Jie E. Yang, Yixuan J. Hou, Ralph Baric, Elizabeth R. Wright, Yoshihiro Kawaoka, Ravi S. Kane
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104341- (2022)
Summary: Background: The COVID-19 pandemic continues to cause morbidity and mortality worldwide. Most approved COVID-19 vaccines generate a neutralizing antibody response that primarily targets the highly variable receptor-binding domain (RBD) of the
Externí odkaz:
https://doaj.org/article/d7471206528645209e55180d68b770cc
Autor:
Shiho Chiba, Steven J. Frey, Peter J. Halfmann, Makoto Kuroda, Tadashi Maemura, Jie E. Yang, Elizabeth R. Wright, Yoshihiro Kawaoka, Ravi S. Kane
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Chiba et al. describe the use of MS2 bacteriophage coat proteins to develop nanocarriers that display the SARS-CoV-2 spike proteins multivalently for vaccine applications. The vaccine elicited high neutralizing antibody titers and protected Syrian ha
Externí odkaz:
https://doaj.org/article/eccc0e36630d4307b1d6da12b00abf09
Autor:
Zunlong Ke, Joshua D. Strauss, Cheri M. Hampton, Melinda A. Brindley, Rebecca S. Dillard, Fredrick Leon, Kristen M. Lamb, Richard K. Plemper, Elizabeth R. Wright
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Virus assembly is technically challenging to study. Here the authors use cryo-electron tomography of measles virus-infected human cells to determine native-state virus structure and they locate well-ordered M lattices that organize viral glycoprotein
Externí odkaz:
https://doaj.org/article/8cf6586c2905457c8522577aa118213b
Autor:
Christopher C. Stobart, Christina A. Rostad, Zunlong Ke, Rebecca S. Dillard, Cheri M. Hampton, Joshua D. Strauss, Hong Yi, Anne L. Hotard, Jia Meng, Raymond J. Pickles, Kaori Sakamoto, Sujin Lee, Michael G. Currier, Syed M. Moin, Barney S. Graham, Marina S. Boukhvalova, Brian E. Gilbert, Jorge C. G. Blanco, Pedro A. Piedra, Elizabeth R. Wright, Martin L. Moore
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Development of a safe and efficacious vaccine for respiratory syncytial virus (RSV) has been challenging. Here the authors generate a live-attenuated RSV vaccine that shows increased thermostability and immunogenicity, and protects cotton rats from R
Externí odkaz:
https://doaj.org/article/2a61be93aec04ad3a0b22213856c0d55
Autor:
Binh Ha, Jie E. Yang, Xuemin Chen, Samadhan J. Jadhao, Elizabeth R. Wright, Larry J. Anderson
Publikováno v:
Viruses, Vol 12, Iss 9, p 906 (2020)
Respiratory syncytial virus (RSV) causes substantial lower respiratory tract disease in children and at-risk adults. Though there are no effective anti-viral drugs for acute disease or licensed vaccines for RSV, palivizumab prophylaxis is available f
Externí odkaz:
https://doaj.org/article/d3fa709c14b04983b7aa93906629ff8f