Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Elizabeth R. Sharlow"'
Autor:
Elizabeth R. Sharlow, Danielle C. Llaneza, William E. Grever, Garnett A. Mingledorff, Anna J. Mendelson, George S. Bloom, John S. Lazo
Publikováno v:
SLAS Discovery, Vol 28, Iss 6, Pp 275-283 (2023)
Human induced pluripotent stem cell (iPSC)-derived neurons are being increasingly used for high content imaging and screening. However, iPSC-derived neuronal differentiation and maturation is time-intensive, often requiring >8 weeks. Unfortunately, t
Externí odkaz:
https://doaj.org/article/d14cfbcac61844679a8e3bf159917758
Autor:
Elizabeth R. Sharlow
Publikováno v:
SLAS Discovery, Vol 28, Iss 6, Pp 247-248 (2023)
Externí odkaz:
https://doaj.org/article/43d93bef73fd49bf8666e1b747c4bd71
Autor:
John S. Lazo, Elizabeth R. Sharlow, Robert Cornelison, Duncan J. Hart, Danielle C. Llaneza, Anna J. Mendelson, Ettore J. Rastelli, Nikhil R. Tasker, Charles N. Landen, Peter Wipf
Publikováno v:
Biomolecules, Vol 11, Iss 7, p 969 (2021)
High grade serous ovarian cancer (OvCa) frequently becomes drug resistant and often recurs. Consequently, new drug targets and therapies are needed. Bioinformatics-based studies uncovered a relationship between high Protein Tyrosine Phosphatase of Re
Externí odkaz:
https://doaj.org/article/bd03bd9e93c14cfb8f63e736838dafd7
Autor:
Marie-Céline Frantz, Karla Bravo-Altamirano, Courtney R. LaValle, Manuj Tandon, Stephanie Leimgruber, Elizabeth R. Sharlow, John S. Lazo, Q. Jane Wang, Peter Wipf, Kara M. George
Publikováno v:
Pharmaceutics, Vol 3, Iss 2, Pp 186-228 (2011)
Protein kinase D (PKD) belongs to a family of serine/threonine kinases that play an important role in basic cellular processes and are implicated in the pathogenesis of several diseases. Progress in our understanding of the biological functions of PK
Externí odkaz:
https://doaj.org/article/3c427ce19ca647e69b452ac7dd756d47
Autor:
John S. Lazo, Kelly N. Isbell, Sai Ashish Vasa, Danielle C. Llaneza, Ettore J. Rastelli, Peter Wipf, Elizabeth R. Sharlow
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 384:429-438
Autor:
Guillermo, Eastman, Elizabeth R, Sharlow, John S, Lazo, George S, Bloom, José R, Sotelo-Silveira
Publikováno v:
Journal of Alzheimer's Disease. 86:365-386
Background: Defining cellular mechanisms that drive Alzheimer’s disease (AD) pathogenesis and progression will be aided by studies defining how gene expression patterns change during pre-symptomatic AD and ensuing periods of declining cognition. Pr
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Elizabeth R. Sharlow, Danielle C. Llaneza, William E. Grever, Garnett A. Mingledorff, Anna J. Mendelson, George S. Bloom, John S. Lazo
Publikováno v:
SLAS Discovery.
Human induced pluripotent stem cell (iPSC)-derived neurons are being increasingly used for high content imaging and screening. However, iPSC-derived neuronal differentiation and maturation is time-intensive, often requiring8 weeks. Unfortunately, the
Publikováno v:
The FASEB Journal. 36
Autor:
Mara Kreishman-Deitrick, Richard J. Sciotti, Brian Vesely, Jason C. Sousa, Elizabeth R. Sharlow, Patricia J. Lee, Tesfaye Teshome, John S. Lazo, Mozna Khraiwesh, Erica Penn, Brandon S. Pybus, Chau Vuong, Susan E. Leed, Diana Caridha, Gustave Bonkoungou
Publikováno v:
ACS Infectious Diseases. 7:506-517
Cutaneous leishmaniasis (CL) is the most common form of leishmaniasis affecting human populations, yet CL remains largely ignored in drug discovery programs. CL causes disfiguring skin lesions and often relapses after "clinical cure" using existing t