Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Elizabeth R. Lotsof"'
Autor:
Elizabeth R. Lotsof, Allison E. Krajewski, Brittany Anderson-Steele, JohnPatrick Rogers, Lanxin Zhang, Jongchan Yeo, Savannah G. Conlon, Amelia H. Manlove, Jeehiun K. Lee, Sheila S. David
Publikováno v:
J Am Chem Soc
Journal of the American Chemical Society, vol 144, iss 32
Journal of the American Chemical Society, vol 144, iss 32
A-to-I RNA editing is widespread in human cells but is uncommon in the coding regions of proteins outside the nervous system. An unusual target for recoding by the adenosine deaminase ADAR1 is the pre-mRNA of the base excision DNA repair enzyme NEIL1
Autor:
Sheila S. David, Eric T. Kool, Savannah G. Conlon, Yong Woong Jun, Elizabeth R. Lotsof, David L. Wilson, Anna M. Kietrys
Publikováno v:
Angew Chem Int Ed Engl
Direct measurement of DNA repair enzyme activities is important both for the basic study of cellular repair pathways as well as for potential new translational applications in their associated diseases. NTH1, a major glycosylase targeting oxidized py
Publikováno v:
Biochemistry
Biochemistry, vol 60, iss 19
Biochemistry, vol 60, iss 19
Editing of the pre-mRNA of the DNA repair glycosylase NEIL1 results in substitution of a Lys with Arg in the lesion recognition loop of the enzyme. Unedited (UE, Lys242) NEIL1 removes thymine glycol lesions in DNA ∼30 times faster than edited (Ed,
Autor:
Eric T. Kool, Anna M. Kietrys, Sheila S. David, Elizabeth R. Lotsof, Yong Woong Jun, David L. Wilson, Savannah G. Conlon
Publikováno v:
Angewandte Chemie. 132:17479-17479