Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Elizabeth R. Bergert"'
Autor:
John C. Morris, Michael K. O'Connor, Roisin M. Dwyer, Elizabeth R. Bergert, Sandra J. Gendler
Publikováno v:
Human Gene Therapy. 17:661-668
Pancreatic cancer is the fourth leading cause of cancer death in the United States. It is highly aggressive with no uniformly effective chemotherapy available for metastatic disease. The sodium-iodide symporter (NIS) is a transmembrane protein respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9617648c221365fc2b118961bdc927f
https://doi.org/10.1089/hum.2006.17.661
https://doi.org/10.1089/hum.2006.17.661
Autor:
Neziha Cengic, Christine Spitzweg, I V Scholz, John C. Morris, Richard G. Vile, Kevin J. Harrington, Claire H. Baker, Elizabeth R. Bergert, Burkhard Göke, K Maletz
Publikováno v:
Gene Therapy. 12:272-280
We investigated the feasibility of using radioiodine therapy in colon carcinoma cells (HCT 116) following tumor-specific expression of the human sodium iodide symporter (hNIS) using the carcinoembryonic antigen (CEA) promoter. HCT 116 cells were stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9e86a0e7dc6d152ee5d5a835ffd9c1
https://doi.org/10.1038/sj.gt.3302410
https://doi.org/10.1038/sj.gt.3302410
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:5627-5632
The ability of thyroid cancers to concentrate radioiodine (RAI) is dependent, in part, upon the expression and functional integrity of the sodium iodide symporter (NIS). However, some differentiated thyroid carcinomas (DTCs) and most undifferentiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b753dd6c82770ebbf2342470d54fcb5
https://doi.org/10.1210/jcem.86.11.8048
https://doi.org/10.1210/jcem.86.11.8048
Publikováno v:
Current Opinion in Endocrinology & Diabetes. 8:259-265
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::322c5ecc69ea7cc987732ecf520c7f8c
https://doi.org/10.1097/00060793-200110000-00006
https://doi.org/10.1097/00060793-200110000-00006
Autor:
Elizabeth R. Bergert, John C. Morris, Charyl M. Dutton, Armin E. Heufelder, John R. Goellner, Maria R. Castro, Christine Spitzweg
Publikováno v:
Kidney International. 59(3):1013-1023
Expression of the sodium iodide symporter in human kidney. Background The human sodium iodide symporter (hNIS) is a transmembrane protein that mediates the active transport of iodide in the thyroid gland. Following cloning of NIS, NIS expression has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b537d64f0e9685353a3b64a11e3673b
Autor:
Ephraim M. Gabriel, Clive S. Grant, Elizabeth R. Bergert, John C. Morris, Jonathan A. van Heerden, Geoffrey B. Thompson
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 84:3328-3335
Toxic multinodular goiter (TMNG) represents a frequent cause of endogenous hyperthyroidism, affecting 5-15% of such patients (with higher frequencies reported in iodine-deficient areas of the world). Although mutations of human TSH receptor (hTSHR) h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::052bef492f30e91a214469522f53d935
https://doi.org/10.1210/jcem.84.9.5966
https://doi.org/10.1210/jcem.84.9.5966
Autor:
Bryan McIver, John R. Goellner, John C. Morris, Thomas G. Beito, Elizabeth R. Bergert, M. Regina Castro
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 84:2957-2962
The thyroid sodium-iodide symporter (NIS) is responsible for iodide concentrating ability within thyroid follicular cells. We sought to develop monoclonal antibodies against human NIS (hNIS) for use as reagents in structure-function studies of the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bddfb595a4a3fc2b16359ede488303ca
https://doi.org/10.1210/jcem.84.8.5871
https://doi.org/10.1210/jcem.84.8.5871
Publikováno v:
Nature Biotechnology. 15:439-443
Chimeric analogs derived from pairs of homologous proteins routinely exhibit activities found in one or both parents. We describe chimeras of two glycoprotein hormones, human chorionic gonadotropin (hCG) and human follitropin (hFSH), that exhibit act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab88aeb8b4c0e9f28d679a12ea75114
https://doi.org/10.1038/nbt0597-439
https://doi.org/10.1038/nbt0597-439
Publikováno v:
Autoimmunity. 22:69-79
To examine the interaction of immunoglobulins from patients with newly diagnosed hypothyroidism with the TSH receptor (TSHr), we tested protein-A purified IgG in an ELISA assay with a series of peptides representing the entire extracellular domain (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551bf5435e2df55b6b260157349e6aa8
https://doi.org/10.3109/08916939508995302
https://doi.org/10.3109/08916939508995302
Publikováno v:
Journal of Biological Chemistry. 269:30935-30938
The amino acid sequence 256-275 of the human thyrotropin (TSH) receptor extracellular domain has previously been shown to participate in a high affinity TSH binding site by a synthetic peptide approach as well as by site-directed mutagenesis. To furt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4fb588f4f289c99ebda6e43da3b4153
https://doi.org/10.1016/s0021-9258(18)47371-1
https://doi.org/10.1016/s0021-9258(18)47371-1