Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elizabeth R Dufficy"'
Autor:
Lyra O Randzavola, Paige M Mortimer, Emma Garside, Elizabeth R Dufficy, Andrea Schejtman, Georgia Roumelioti, Lu Yu, Mercedes Pardo, Kerstin Spirohn, Charlotte Tolley, Cordelia Brandt, Katherine Harcourt, Esme Nichols, Mike Nahorski, Geoff Woods, James C Williamson, Shreehari Suresh, John M Sowerby, Misaki Matsumoto, Celio XC Santos, Cher Shen Kiar, Subhankar Mukhopadhyay, William M Rae, Gordon J Dougan, John Grainger, Paul J Lehner, Michael A Calderwood, Jyoti Choudhary, Simon Clare, Anneliese Speak, Giorgia Santilli, Alex Bateman, Kenneth GC Smith, Francesca Magnani, David C Thomas
Publikováno v:
eLife, Vol 11 (2022)
EROS (essential for reactive oxygen species) protein is indispensable for expression of gp91phox, the catalytic core of the phagocyte NADPH oxidase. EROS deficiency in humans is a novel cause of the severe immunodeficiency, chronic granulomatous dise
Externí odkaz:
https://doaj.org/article/1b48b81ab31e44d4a2884318ac761009
Autor:
Maria Rita Fabbrizi, Thomas J. Doggett, Jonathan R. Hughes, Emma Melia, Elizabeth R. Dufficy, Rhianna M. Hill, Amalia Goula, Ben Phoenix, Jason L. Parsons
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Ionising radiation (IR) is widely used in cancer treatment, including for head and neck squamous cell carcinoma (HNSCC), where it induces significant DNA damage leading ultimately to tumour cell death. Among these lesions, DNA double strand
Externí odkaz:
https://doaj.org/article/f8e0778641584cd48be2aa428cb231dc
Autor:
Paige M Mortimer, Lyra O Randzavola, Emma Garside, Elizabeth R Dufficy, Andrea Schejtman, Georgia Roumelioti, Lu Yu, Mercedes Pardo, Kerstin Spirohn, Charlotte Tolley, Cordelia Brandt, Katherine Harcourt, Esme Nichols, Mike Nahorski, Geoff Woods, James C Williamson, Shreehari Suresh, John M Sowerby, Misaki Matsumoto, Celio XC Santos, Cher Shen Kiar, Subhankar Mukhopadhyay, William M Rae, Gordon J Dougan, John Grainger, Paul J Lehner, Michael A Calderwood, Jyoti Choudhary, Simon Clare, Anneliese Speak, Giorgia Santilli, Alex Bateman, Kenneth GC Smith, Francesca Magnani, David C Thomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ed7b8a23462d0bf93707f8ec4f553fd
https://doi.org/10.7554/elife.76387.sa2
https://doi.org/10.7554/elife.76387.sa2
Autor:
Elizabeth R. Dufficy, Karan Sharma, Maria Pilar Sanchez-Bailon, Grant S. Stewart, Kelly Chiang, Sarah L. Maslen, Soo-Youn Choi, Emma A. Gunnell, Clare C. Davies, Debashish Sahay, Ingrid Dreveny, Gavin S. McNee, J. Mark Skehel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
Cross-talk between distinct protein post-translational modifications is critical for an effective DNA damage response. Arginine methylation plays an important role in maintaining genome stability, but how this modification integrates with other enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be0c226075a1ed2bb9cfe81e979b0a9
https://nottingham-repository.worktribe.com/file/6681867/1/S41467-021-26413-6
https://nottingham-repository.worktribe.com/file/6681867/1/S41467-021-26413-6
Autor:
Hamoud Al-Mousa, James Lee, Giorgia Santilli, Kenneth G. C. Smith, Fowzan S. Alkuraya, Eve L. Coomber, Louis-Marie Charbonnier, Hasan Al-Dhekri, Anneliese O. Speak, Simon Clare, Anne E. Beenken, Andrea Schejtman, Elizabeth R. Dufficy, Talal A. Chatila, David C. Thomas, Adrian J. Thrasher
Short Summary The phagocyte respiratory burst is mediated by the phagocyte NADPH oxidase, a multi-protein subunit complex that facilitates production of reactive oxygen species and which is essential for host defence. Monogenic deficiency of individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea18756fea7700da80dce61c8c05c33a
Autor:
Beenken Ae, Eve L. Coomber, Elizabeth R. Dufficy, Talal A. Chatila, Hamoud Al-Mousa, Simon Clare, Anneliese O. Speak, Fowzan S. Alkuraya, David C. Thomas, Giorgia Santilli, James Lee, Adrian J. Thrasher, Hasan Al-Dhekri, Louis-Marie Charbonnier, Smith Kg, Andrea Schejtman
The phagocyte respiratory burst is mediated by the phagocyte NADPH oxidase, a multi-protein subunit complex that facilitates production of reactive oxygen species and which is essential for host defence. Monogenic deficiency of individual subunits le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6cf1f446db5abb7def433eab68f5050
https://doi.org/10.1101/331454
https://doi.org/10.1101/331454
Autor:
Maria Pilar Sanchez-Bailon, Soo-Youn Choi, Elizabeth R. Dufficy, Karan Sharma, Gavin S. McNee, Emma Gunnell, Kelly Chiang, Debashish Sahay, Sarah Maslen, Grant S. Stewart, J. Mark Skehel, Ingrid Dreveny, Clare C. Davies
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Post-translational modifications are critical for regulating the DNA damage response. Here, the authors identify a methylation-deubiquitination crosstalk between methyltransferase PRMT1 and deubiquitinase USP11, showing that the enzymes regulate each
Externí odkaz:
https://doaj.org/article/ea281da007d54673887d7d80ba9fed3c