Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Elizabeth R, Fischer"'
Autor:
Rachel Erickson, Chang Huang, Cameron Allen, Joanna Ireland, Gwynne Roth, Zhongcheng Zou, Jinghua Lu, Bernard A. P. Lafont, Nicole L. Garza, Beniah Brumbaugh, Ming Zhao, Motoshi Suzuki, Lisa Olano, Joseph Brzostowski, Elizabeth R. Fischer, Homer L. Twigg, Reed F. Johnson, Peter D. Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Severe COVID-associated lung injury is a major confounding factor of hospitalizations and death with no effective treatments. Here, we describe a non-classical fibrin clotting mechanism mediated by SARS-CoV-2 infected primary lung but not ot
Externí odkaz:
https://doaj.org/article/dfb1e8c9aa3047e59958ec0f9d7a69ea
Autor:
Joanna Ireland, Jason Segura, Genbin Shi, Julianna Buchwald, Gwynne Roth, Thomas Juncheng Shen, Ruipeng Wang, Xinhua Ji, Elizabeth R. Fischer, Susan Moir, Tae-Wook Chun, Peter D. Sun
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
HIV-1 gp120 glycan binding to C-type lectin adhesion receptor L-selectin/CD62L on CD4 T cells facilitates viral attachment and entry. Paradoxically, the adhesion receptor impedes HIV-1 budding from infected T cells and the viral release requires the
Externí odkaz:
https://doaj.org/article/d1345b938a9e4d4b9d8558446242fdc7
Autor:
Ousmane H. Cissé, Shelly J. Curran, H. Diego Folco, Yueqin Liu, Lisa Bishop, Honghui Wang, Elizabeth R. Fischer, A. Sally Davis, Christian Combs, Sabrina Thapar, John P. Dekker, Shiv Grewal, Melanie Cushion, Liang Ma, Joseph A. Kovacs
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Centromeres are constricted chromosomal regions that are essential for cell division. In eukaryotes, centromeres display a remarkable architectural and genetic diversity. The basis of centromere-accelerated evolution remains elusive. Here, w
Externí odkaz:
https://doaj.org/article/b90416d035844a13812402c4d792a37f
Autor:
Hong-Su Park, Yumiko Matsuoka, Cindy Luongo, Lijuan Yang, Celia Santos, Xueqiao Liu, Laura R. H. Ahlers, Ian N. Moore, Sharmin Afroz, Reed F. Johnson, Bernard A. P. Lafont, David W. Dorward, Elizabeth R. Fischer, Craig Martens, Siba K. Samal, Shirin Munir, Ursula J. Buchholz, Cyril Le Nouën
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Current vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are administered parenterally and appear to be more protective in the lower versus the upper respiratory tract. Vaccines are needed that directly stimulate
Externí odkaz:
https://doaj.org/article/b63359b706ef44b6802329d81a42cb7c
Autor:
Ted Hackstadt, Abhilash I. Chiramel, Forrest H. Hoyt, Brandi N. Williamson, Cheryl A. Dooley, Paul A. Beare, Emmie de Wit, Sonja M. Best, Elizabeth R. Fischer
Publikováno v:
Viruses, Vol 13, Iss 9, p 1798 (2021)
A variety of immunolabeling procedures for both light and electron microscopy were used to examine the cellular origins of the host membranes supporting the SARS-CoV-2 replication complex. The endoplasmic reticulum has long been implicated as a sourc
Externí odkaz:
https://doaj.org/article/da0bb646eddd4b82911ad4eb61c121bb
Autor:
Jeffrey M. Grabowski, Olof R. Nilsson, Elizabeth R. Fischer, Dan Long, Danielle K. Offerdahl, Yoonseong Park, Dana P. Scott, Marshall E. Bloom
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT The Ixodes scapularis tick transmits a number of pathogens, including tick-borne flaviviruses (TBFVs). In the United States, confirmed human infections with the Powassan virus (POWV) TBFV have a fatality rate of ∼10% and are increasing in
Externí odkaz:
https://doaj.org/article/d5b4c31c286a40738c8bcc9fc51a56c2
Autor:
Ousmane H. Cissé, Shelly Curran, H. Diego Folco, Yueqin Liu, Lisa Bishop, Honghui Wang, Elizabeth R. Fischer, A Sally Davis, Spenser Babb-Biernacki, Vinson P. Doyle, Jonathan K. Richards, Sergio A. Hassan, John P. Dekker, Pavel P. Khil, Jason M. Brenchley, Shiv Grewal, Melanie Cushion, Liang Ma, Joseph A. Kovacs
Centromeres are genomic regions that coordinate accurate chromosomal segregation during mitosis and meiosis. Yet, despite their essential function, centromeres evolve rapidly across eukaryotes. Centromeres are often the sites of chromosomal breaks wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae74d5da4384d70d9f62db3caa8e9b3f
https://doi.org/10.1101/2023.05.12.540427
https://doi.org/10.1101/2023.05.12.540427
Autor:
Karl J. Erlandson, Himani Bisht, Andrea S. Weisberg, Seong-In Hyun, Bryan T. Hansen, Elizabeth R. Fischer, Jenny E. Hinshaw, Bernard Moss
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2084-2091 (2016)
Poxviruses are enveloped DNA viruses that replicate within the cytoplasm. The first viral structures are crescents and spherical particles, with a lipoprotein membrane bilayer, that are thought to be derived from the ER. We determined that A17, a con
Externí odkaz:
https://doaj.org/article/423eccfbd9f140c8ab1d6cd1e941ae00
Autor:
Karen Laky, Jessica L. Kinard, Jenny Min Li, Ian N. Moore, Justin Lack, Elizabeth R. Fischer, Juraj Kabat, Rachel Latanich, Nicholas C. Zachos, Ajinkya R. Limkar, Katherine A. Weissler, Robert W. Thompson, Thomas A. Wynn, Harry C. Dietz, Anthony L. Guerrerio, Pamela A. Frischmeyer-Guerrerio
Publikováno v:
Sci Immunol
Allergic diseases are a global health challenge. Individuals harboring loss-of-function variants in transforming growth factor–β receptor (TGFβR) genes have an increased prevalence of allergic disorders, including eosinophilic esophagitis. Allerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ece60dded1e0e7086d4659735c67b06
https://europepmc.org/articles/PMC10106118/
https://europepmc.org/articles/PMC10106118/
Autor:
Puthupparampil V Scaria, Beth Chen, Christopher G Rowe, David S Jones, Emma Barnafo, Elizabeth R Fischer, Charles Anderson, Nicholas J MacDonald, Lynn Lambert, Kelly M Rausch, David L Narum, Patrick E Duffy
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190312 (2017)
Chemical conjugation of polysaccharide to carrier proteins has been a successful strategy to generate potent vaccines against bacterial pathogens. We developed a similar approach for poorly immunogenic malaria protein antigens. Our lead candidates in
Externí odkaz:
https://doaj.org/article/2a694a1e2ca147cf9e3a3357db15e749