Výsledky vyhledávání - "Elizabeth Purssell"

Assessing the need for resuscitative endovascular balloon occlusion of the aorta (REBOA) for management of non-compressible hemorrhage at a Canadian urban trauma centre: a retrospective chart review

Autor: Elizabeth Purssell, John Taylor, Vesna Ivkov, Joseph Haegert, Sean Patrick

Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a less invasive alternative to resuscitative thoracotomy (RT) for life threatening, infra-diaphragmatic, non-compressible hemorrhage from trauma. Existing evidence surrou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9a2487869eeee505125c24666b0453f
https://doi.org/10.21203/rs.3.rs-836732/v1

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Assessing the need for resuscitative endovascular balloon occlusion of the aorta (REBOA) for management of non-compressible hemorrhage at a Canadian urban trauma centre

Autor: Joseph Haegert, Sean Patrick, John Taylor, Elizabeth Purssell, Vesna Ivkov

Introduction Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a less invasive alternative to resuscitative thoracotomy (RT) for life threatening, infra-diaphragmatic, non-compressible hemorrhage from trauma. Existing evidence surr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acd22300606859f9f9bc6c3bd4f03b11
https://doi.org/10.21203/rs.3.rs-198760/v1

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Naloxone dosing in the era of ultra-potent opioid overdoses: a systematic review

Autor: Jason Curran, Jesse Godwin, Penelope M. A. Brasher, Elizabeth Purssell, Fiona O'Sullivan, Mary M. Doyle-Waters, Corinne M. Hohl, Roy Purssell, Jane A. Buxton, Jessica Moe, Jeffrey P. Hau

Publikováno v: CJEM. 22(2)

ObjectivesEvaluate the relationship between naloxone dose (initial and cumulative) and opioid toxicity reversal and adverse events in undifferentiated and presumed fentanyl/ultra-potent opioid overdoses.MethodsWe searched Embase, MEDLINE, Cochrane Ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67dea1c2df16e3b868a47c7f3507c15
https://pubmed.ncbi.nlm.nih.gov/31955714

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In UteroDimethadione Exposure Causes Postnatal Disruption in Cardiac Structure and Function in the Rat

Autor: Terence R.S. Ozolinš, Elizabeth Purssell, Michael A. Adams, Kristiina L. Aasa

Publikováno v: Toxicological Sciences. 142:350-360

In utero exposure of rat embryos to dimethadione (DMO), the N-demethylated teratogenic metabolite of the anticonvulsant trimethadione, induces a high incidence of cardiac heart defects including ventricular septal defects (VSDs). The same exposure re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755980aacce848392f24dba178e13992
https://doi.org/10.1093/toxsci/kfu190

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Minor Injury Crashes: Prevalence of Driver-Related Risk Factors and Outcome

Autor: Daniel K. Ting, Jeffrey R. Brubacher, Benjamin Tuyp, Vahid Mehrnoush, Herbert Chan, Elizabeth Purssell

Publikováno v: The Journal of emergency medicine. 52(5)

Background The majority of crashes cause “minor” injuries (i.e., treated and released from the emergency department [ED]). Minor injury crashes are poorly studied. Objectives This study aims to determine the prevalence of driver-related risk fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec110ba9ca5e7a39e5ebfe62525d00c6
https://pubmed.ncbi.nlm.nih.gov/28283304

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Comparison of Rates of Coronary Angiography and Combined Testing Procedures in Patients Seen in the Emergency Room With Chest Pain (But No Objective Acute Coronary Syndrome Findings) Having Coronary Computed Tomography Versus Exercise Stress Testing

Autor: Kimchi Nguyen, Elizabeth Purssell, Rekha Raju, Brett Heilbron, Philipp Blanke, Frank X. Scheuermeyer, Jonathon Leipsic, Naomi Kasteel, Mikameh Kazem, Carolyn Taylor, Brian Grunau, Christopher Naoum

Publikováno v: The American journal of cardiology. 118(2)

Coronary computed tomography angiography (CCTA) appears comparable to standard care, including exercise stress testing (EST), in diagnosing acute coronary syndrome in emergency department (ED) patients with chest pain but may increase downstream test

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebbfef132896e65dc4b755585f06a82
https://pubmed.ncbi.nlm.nih.gov/27236251

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Maternal rat serum concentrations of dimethadione do not explain intra-litter differences in the incidence of dimethadione-induced birth defects, including novel findings in foetal lung

Autor: Allison Rutter, Ian Rodger, Elizabeth Purssell, Isabel Lam, Mesha Thompson, Terence R.S. Ozolinš

Publikováno v: Toxicology. 326

To investigate mechanisms of chemical-induced congenital heart defects (CHD) we have developed a rat model using dimethadione (DMO), the N-demethylated metabolite of the anticonvulsant, trimethadione (TMD). Dosing pregnant rats with 300 mg/kg DMO eve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c62dc3d5866b16d680d4d66c1b933c
https://pubmed.ncbi.nlm.nih.gov/25446330

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Noninvasive high-resolution ultrasound reveals structural and functional deficits in dimethadione-exposed fetal rat hearts in utero

Autor: Terence R.S. Ozolinš, Jason J. Thomson, Nigel A. Brown, Andrea D. Weston, Elizabeth Purssell, Terri A. Swanson

Publikováno v: Birth Defects Research Part B: Developmental and Reproductive Toxicology.

BACKGROUND We previously showed dimethadione (DMO), the N-demethylated metabolite of the anticonvulsant trimethadione, induces ventricular septation defects (VSD) and other heart anomalies in rat (Weston et al., 2011). Because of the relationship bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06af9e82bddd229ab3b9f9f46abba57f
https://doi.org/10.1002/bdrb.20339

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