Výsledky vyhledávání - "Elizabeth Poynor"

Supplementary Methods and Figure Legend from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer

Autor: Lucio Luzzatto, Andrew Koff, Dionyssios Katsaros, Giorgio Cattoretti, Michela Romano, Eugenio Erba, Maurizio D’Incalci, Cecilia Bussani, Luca Porcu, Robert Fruscio, Michela Cinquini, Luca Clivio, Richard R. Barakat, Elizabeth Poynor, Sergio Marchini

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85418aa27c858ecd99254eb11cd057b4
https://doi.org/10.1158/1078-0432.22447329

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Data from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer

Purpose: Epithelial ovarian tumors (EOT) are among the most lethal of malignancies in women. We have previously identified ZIC2 as expressed at a higher level in samples of a malignant form (MAL) of EOT than in samples of a form with low malignant po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fa379a04647701361ded5eb253cd70
https://doi.org/10.1158/1078-0432.c.6521037

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Supplementary Table 2 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer

PDF file, 62K, A. List of primer pair sequences used for RT-qPCR analysis and respective annealing temperatures. B. List of siRNA sequences used. C. Details of deletion constructs (see Fig. 4A).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249a21299da448a928445f109d28c515
https://doi.org/10.1158/1078-0432.22447320

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Supplementary Figure 2 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer

PDF file, 96K, Role in transformation of individual domains of ZIC2 protein assessed by deletion analysis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bc5ef03a8b49153bbed308f48b3529
https://doi.org/10.1158/1078-0432.22447332

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Supplementary Figure 1 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer

PDF file, 198K, Forced over-expression of ZIC2 in NIH-3T3 cells produces increased cell proliferation and knockdown of ZIC2 protein inhibits proliferation of ovarian cancer cell lines.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbb8a5b8cd4a6f0e453be478a21bfc7
https://doi.org/10.1158/1078-0432.22447335

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Supplementary Table 4 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer

PDF file, 82K, Univariate analysis. Linear regression analysis between histopathological features and ZIC2 expression. Units are 103 multiplied.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e501892220fd3064cf9400107a680b6
https://doi.org/10.1158/1078-0432.22447314

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Supplementary Table 1 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer

PDF file, 87K, Main characteristics of patients and tissues. A, clinical and histopathological parameters of the 232 EOT biopsies enrolled in the study and subdivided into tumor tissue collection A and B. UK unknown. n, number of patients enrolled. N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b72d094f57ad1ba13ea7e46cd5393c
https://doi.org/10.1158/1078-0432.22447326

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Supplementary Table 3 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer

PDF file, 61K, qRT-PCR and densitometric analysis of ZIC2 expression. R is the ratio of the median distribution of ZIC2 expression levels measured by real time qRT-PCR or Western Blot in the MAL biopsies compared to the LMP biopsies or between stage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f90cc5217620d4d99fe41ffd874477b
https://doi.org/10.1158/1078-0432.22447317.v1

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