Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elizabeth Pongo"'
Autor:
Anand Panchal, Pui Seto, Russell Wall, Brian J. Hillier, Ying Zhu, Jessica Krakow, Aakash Datt, Elizabeth Pongo, Andisheh Bagheri, Tseng-Hui T. Chen, Jeremiah D. Degenhardt, Patricia A. Culp, Danielle E. Dettling, Maia V. Vinogradova, Chad May, Robert B. DuBridge
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Conditionally active COBRA™ (COnditional Bispecific Redirected Activation) T cell engagers are engineered to overcome the limitations of inherently active first-generation T cell engagers, which are unable to discern between tumor and healthy tissu
Externí odkaz:
https://doaj.org/article/f2605ce7f19c42fe8f1f08cf99498254
Autor:
Maia Vinogradova, Danielle E. Dettling, Russell Wall, Jessica L. Krakow, Aakash Datt, Elizabeth Pongo, Tseng-Hui T Chen, Andisheh Bagheri, Brian J. Hillier, Patricia Culp, Ying Zhu, Chad May, Robert B. Dubridge, Jeremiah D. Degenhardt, Pui Seto, Anand Panchal
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Conditionally active COBRA™ (COnditional Bispecific Redirected Activation) T cell engagers are engineered to overcome the limitations of inherently active first-generation T cell engagers, which are unable to discern between tumor and healthy tissu
Autor:
Catarina Tran, John Corbin, Ira D. Goldfine, Toshihiko Takeuchi, David J. Bohmann, Elizabeth Pongo, Vinay Bhaskar, Genevieve Nonet, Kristen Michelson, Arnold Horwitz, Jingsong Zhao, Mark L. White, Resi B. Gerstner
Publikováno v:
Obesity. 24:1687-1694
Objective Leptin (LEP) deficiency results in major metabolic perturbations, including obesity, dyslipidemia, and diabetes. Although LEP deficiency can be treated with daily injections of a recombinant LEP, generation of an antibody activating the LEP
Autor:
Fangjiu Zhang, Fraser Conrad, Consuelo Garcia-Rodriquez, Sujeewa D. Wijesuriya, Milan T. Tomic, Shauna Farr-Jones, Elizabeth Pongo, James D. Marks, Arnold Horwitz
Publikováno v:
Protein expression and purification. 149
Expression variation among antibodies produced by stably transfected Chinese Hamster Ovary (CHO) cells is well established. While developing CHO-K1 cell lines, we encountered a human monoclonal antibody, mAb B-c, with severe manufacturability issues,
Autor:
Vinay, Bhaskar, Ira D, Goldfine, Resi, Gerstner, Kristen, Michelson, Catarina, Tran, Genevieve, Nonet, David, Bohmann, Elizabeth, Pongo, Jingsong, Zhao, Arnold H, Horwitz, Toshihiko, Takeuchi, Mark, White, John A, Corbin
Publikováno v:
Obesity (Silver Spring, Md.). 24(8)
Leptin (LEP) deficiency results in major metabolic perturbations, including obesity, dyslipidemia, and diabetes. Although LEP deficiency can be treated with daily injections of a recombinant LEP, generation of an antibody activating the LEP receptor
Autor:
Paul D. Larsen, Alexander Owyang, Elizabeth Pongo, Marina Roell, Mary Haak-Frendscho, Masahisa Handa, Linda Masat, Hassan Issafras, Kiran Ahluwalia, John Corbin, Arnold Horwitz
Publikováno v:
mAbs. 3:49-60
Interleukin-1β (IL-1β) is a potent mediator of inflammatory responses and plays a role in the differentiation of a number of lymphoid cells. In several inflammatory and autoimmune diseases, serum levels of IL-1β are elevated and correlate with dis
Autor:
Amer M. Mirza, Daniel Bedinger, Raphaël Lévy, Toshihiko Takeuchi, Catarina Tran, Robyn Cotter, Agnes Choppin, Kristin Camfield Lind, Fangjiu Zhang, Lynn Webster, Elizabeth Pongo, Llewelyn Lao, Kirk Johnson, Sujeewa D. Wijesuriya, Rachel A. Hunt, Kiran Ahluwalia
Publikováno v:
Cancer Research. 77:LB-306
Humoral Hypercalcemia of Malignancy (HHM) occurs in 20-30 percent of advanced cancers, both solid tumors and hematologic malignancies, and is the most common life-threatening complication of cancer. HHM is due to tumors secreting abnormally high quan
Autor:
Lin Esposito, Mary Haak-Frendscho, Marina Roell, Paul D. Larsen, John Corbin, Seema Kantak, Alexander Owyang, Elizabeth Pongo, Nathalie Dubois-Stringfellow, David G. Alleva, Linda Masat, Arnold Horwitz, Kiran Ahluwalia, Sandra Vanegas
Publikováno v:
Clinical Immunology. 127:S98-S99