Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Elizabeth P. Williams"'
Publikováno v:
Molecules, Vol 29, Iss 18, p 4457 (2024)
The dynamic landscape of non-canonical DNA G-quadruplex (G4) folding into G-triplex intermediates has led to the study of G-triplex structures and their ability to serve as peroxidase-mimetic DNAzymes. Here we report the formation, stability, and cat
Externí odkaz:
https://doaj.org/article/27fb7559d52543dbb9b0e46e66769955
Autor:
Asmerom T Sengal, Deborah Smith, Cameron E Snell, Samuel Leung, Aline Talhouk, Elizabeth D Williams, Jessica N McAlpine, Pamela M Pollock
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 6, Pp 521-537 (2022)
Abstract Endometrial carcinoma (EC) is the most common gynecological malignancy and fibroblast growth factor receptor 2 (FGFR2) is a frequently dysregulated receptor tyrosine kinase. FGFR2b and FGFR2c are the two main splice isoforms of FGFR2 and are
Externí odkaz:
https://doaj.org/article/4847d837df14472782a00eb999c1ccf3
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background While prostate cancer (PCa) cells most often metastasize to bone in men, species-specific differences between human and mouse bone marrow mean that this pattern is not faithfully replicated in mice. Herein we evaluated the impact
Externí odkaz:
https://doaj.org/article/ca4fc3a92e094c4ca0359e034b49e9dd
Autor:
Orouba Almilaji, Gwilym Webb, Alec Maynard, Thomas P. Chapman, Brian S. F. Shine, Antony J. Ellis, John Hebden, Sharon Docherty, Elizabeth J. Williams, Jonathon Snook
Publikováno v:
Diagnostic and Prognostic Research, Vol 5, Iss 1, Pp 1-11 (2021)
Abstract Background Using two large datasets from Dorset, we previously reported an internally validated multivariable risk model for predicting the risk of GI malignancy in IDA—the IDIOM score. The aim of this retrospective observational study was
Externí odkaz:
https://doaj.org/article/d30c42ad276444d5aca9993d66c490fc
Autor:
B. Duygu Özpolat, Nadine Randel, Elizabeth A. Williams, Luis Alberto Bezares-Calderón, Gabriele Andreatta, Guillaume Balavoine, Paola Y. Bertucci, David E. K. Ferrier, Maria Cristina Gambi, Eve Gazave, Mette Handberg-Thorsager, Jörg Hardege, Cameron Hird, Yu-Wen Hsieh, Jerome Hui, Kevin Nzumbi Mutemi, Stephan Q. Schneider, Oleg Simakov, Hernando M. Vergara, Michel Vervoort, Gáspár Jékely, Kristin Tessmar-Raible, Florian Raible, Detlev Arendt
Publikováno v:
EvoDevo, Vol 12, Iss 1, Pp 1-22 (2021)
Abstract The Nereid Platynereis dumerilii (Audouin and Milne Edwards (Annales des Sciences Naturelles 1:195–269, 1833) is a marine annelid that belongs to the Nereididae, a family of errant polychaete worms. The Nereid shows a pelago-benthic life c
Externí odkaz:
https://doaj.org/article/b10bd03ad68846ba883c6097e2a843f9
Autor:
Khoa A. Tran, Olga Kondrashova, Andrew Bradley, Elizabeth D. Williams, John V. Pearson, Nicola Waddell
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Deep learning is a subdiscipline of artificial intelligence that uses a machine learning technique called artificial neural networks to extract patterns and make predictions from large data sets. The increasing adoption of deep learning acro
Externí odkaz:
https://doaj.org/article/33d450d401724b82944eb82f8918814a
Autor:
Jacqui A. McGovern, Nathalie Bock, Abbas Shafiee, Laure C. Martine, Ferdinand Wagner, Jeremy G. Baldwin, Marietta Landgraf, Christoph A. Lahr, Christoph Meinert, Elizabeth D. Williams, Pamela M. Pollock, Jim Denham, Pamela J. Russell, Gail P. Risbridger, Judith A. Clements, Daniela Loessner, Boris M. Holzapfel, Dietmar W. Hutmacher
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
McGovern et al. establish an orthotopic, humanized prostate cancer model to study bone metastasis. The authors demonstrate that a humanized tumor microenvironment (TME) influences the metastatic spread of cancer cells to tissue-engineered bone, highl
Externí odkaz:
https://doaj.org/article/faf5250036f045d891a483661ad13556
Publikováno v:
NeoBiota, Vol 66, Iss , Pp 55-73 (2021)
Eradication programs for invasive ants are often hampered by a lack of effective tools to detect, contain and kill the pests. Among the range of tools employed in the course of a 20-year eradication program for red imported fire ant, Solenopsis invic
Externí odkaz:
https://doaj.org/article/96a228780ed74e89bc5cae303264e834
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Direct bone marrow injection of cells into murine marrow cavities is used in a range of cell characterization assays and to develop disease models. While human bone marrow-derived stromal cells (hBMSC, also known as mesenchymal st
Externí odkaz:
https://doaj.org/article/7b4a39e1f3c64b07b486c1157fc00828
Autor:
Melissa E. Monterosso, Kathryn Futrega, William B. Lott, Ian Vela, Elizabeth D. Williams, Michael R. Doran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Prostate cancer (PCa) patient-derived xenografts (PDXs) are commonly propagated by serial transplantation of “pieces” of tumour in mice, but the cellular composition of pieces is not standardised. Herein, we optimised a microwell platfor
Externí odkaz:
https://doaj.org/article/2f5eb33aec0547329c75ee64f3601dbc