Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elizabeth P. Messana"'
Publikováno v:
Journal of Neurocytology. 28:913-924
The INK4 and Kip/Cip families of Cyclin Dependent Kinase inhibitors (CKIs) are regulators of the cell cycle. In addition, CKIS including p27Kip1can protect cells from apoptosis in vitro. However, little is known about protective effect of p27Kip1in v
Publikováno v:
Journal of Investigative Dermatology. 105:687-692
Exposure of human and murine melanocytes in vitro to the diacylglycerol (DAG) 1-oleoyl-2-acetyl-sn-glycerol (OAG) markedly increases melanin production within 24 h. To determine whether OAG can increase melanin production in vivo , increasing concent
Autor:
Kara E. May, David C. Mountain, Dominic A. Mangiardi, Elizabeth P. Messana, Katherine McLaughlin-Williamson, Douglas A. Cotanche
Publikováno v:
The Journal of comparative neurology. 475(1)
Aminoglycoside treatment induces caspase-dependent apoptotic death in inner ear sensory hair cells. The timing of apoptotic signaling in sensory hair cells following systemic aminoglycoside treatment has not been characterized in vivo. We administere
Autor:
Mark E. Warchol, David W. Roberson, Asim Haque, Elizabeth P. Messana, J. David Dickman, David Huss, Douglas A. Cotanche, Jonathan I. Matsui, Julie A. Alosi
The sensory hair cells of the inner ear undergo apoptosis after acoustic trauma or aminoglycoside antibiotic treatment, causing permanent auditory and vestibular deficits in humans. Previous studies have demonstrated a role for caspase activation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b742739c9cdaea74cd89fe1fb4e459
https://europepmc.org/articles/PMC6740338/
https://europepmc.org/articles/PMC6740338/
Autor:
Elizabeth P. Messana, Douglas A. Cotanche, Julie A. Alosi, David W. Roberson, Arthur P. Nedder
Publikováno v:
Hearing research. 141(1-2)
Survival surgeries upon chicks are commonly used in auditory research. Appropriate anesthesia is usually obtained with intramuscular or intraperitoneal injections of systemic agents. These techniques have several drawbacks, including delayed onset of
Publikováno v:
Hearing research. 141(1-2)
Models in which a single large systemic dose of gentamicin is used to cause near-synchronous hair cell (HC) loss in the basal end of the chick cochlea have proven increasingly useful in the study of HC regeneration. We quantified the amount of HC dea
Publikováno v:
Hearing research. 113(1-2)
Both sound exposure and gentamicin treatment cause damage to sensory hair cells in the peripheral chick auditory organ, the basilar papilla. This induces a regeneration response which replaces hair cells and restores auditory function. Since function
Publikováno v:
Hearing research. 91(1-2)
Severe acoustic damage in the chick cochlea causes a destruction of both hair cells and supporting cells in a localized area on the basilar papilla. In this region, the sensory cells are replaced by a layer of flattened epithelial cells. We have empl