Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elizabeth Ortner"'
Autor:
Jianfeng Xu, Edward P. Gelmann, William B. Isaacs, James Gruschus, James Ferretti, Patrick C. Walsh, Micheas Zemedkun, Wennuan Liu, Kathy E. Wiley, Jishang Sun, Sarah D. Isaacs, Jielin Sun, Elizabeth Ortner, Bao-li Chang, Jeong-ho Ju, S. Lilly Zheng
Supplementary Figure 1 from Germ-Line Mutation of NKX3.1 Cosegregates with Hereditary Prostate Cancer and Alters the Homeodomain Structure and Function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac925ed0ade03ca7bd10652c6422e65
https://doi.org/10.1158/0008-5472.22365087.v1
https://doi.org/10.1158/0008-5472.22365087.v1
Autor:
Jianfeng Xu, Edward P. Gelmann, William B. Isaacs, James Gruschus, James Ferretti, Patrick C. Walsh, Micheas Zemedkun, Wennuan Liu, Kathy E. Wiley, Jishang Sun, Sarah D. Isaacs, Jielin Sun, Elizabeth Ortner, Bao-li Chang, Jeong-ho Ju, S. Lilly Zheng
NKX3.1, a gene mapped to 8p21, is a member of the NK class of homeodomain proteins and is expressed primarily in the prostate. NKX3.1 exerts a growth-suppressive and differentiating effect on prostate epithelial cells. Because of its known functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17584d99509aeb45fc37a91cde09f7cb
https://doi.org/10.1158/0008-5472.c.6494526
https://doi.org/10.1158/0008-5472.c.6494526
Supplementary Tables 1-2, Figure 1 from NKX3.1 Activates Expression of Insulin-like Growth Factor Binding Protein-3 to Mediate Insulin-like Growth Factor-I Signaling and Cell Proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084160824ac1826cdf69c9969c47f83f
https://doi.org/10.1158/0008-5472.22379880
https://doi.org/10.1158/0008-5472.22379880
NKX3.1 is a homeobox gene that codes for a haploinsufficient prostate cancer tumor suppressor. NKX3.1 protein levels are down-regulated in the majority of primary prostate cancer tissues. NKX3.1 expression in PC-3 cells increased insulin-like growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccaf461c328f2697a463f2cdf51538ad
https://doi.org/10.1158/0008-5472.c.6499377.v1
https://doi.org/10.1158/0008-5472.c.6499377.v1
Autor:
Jing Ma, Hoa N. Hoang, Elizabeth Ortner, Michael Pollak, Gianluca Severi, Vanessa M. Hayes, Meir J. Stampfer, Edward P. Gelmann, Erin Muhlbradt, Graham G. Giles
Publikováno v:
Genescancer. 4(11-12)
NKX3.1 is a tumor suppressor down-regulated in early prostate cancers. A SNP (rs2228013), which represents a polymorphic NKX3.1(C154T) coding for a variant protein NKX3.1(R52C), is present in 10% of the population and is related to prostatic enlargem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2fd7c629547ef54e8710a9ccdf9f860
https://pubmed.ncbi.nlm.nih.gov/24386513
https://pubmed.ncbi.nlm.nih.gov/24386513
