Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Elizabeth N Kornaga"'
Autor:
John M S Bartlett, Jane Bayani, Elizabeth N Kornaga, Patrick Danaher, Cheryl Crozier, Tammy Piper, Cindy Q Yao, Janet A Dunn, Paul C Boutros, Robert C Stein, OPTIMA Trial Management Group
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238593 (2020)
Multiparametric assays for risk stratification are widely used in the management of breast cancer, with applications being developed for a number of other cancer settings. Recent data from multiple sources suggests that different tests may provide di
Externí odkaz:
https://doaj.org/article/b8c93de0973747ecbb1372aabe9a7799
Autor:
Ayan Chanda, Angela Chan, Lili Deng, Elizabeth N Kornaga, Emeka K Enwere, Donald G Morris, Shirin Bonni
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177639 (2017)
Metastasis is the ultimate cause of breast cancer related mortality. Epithelial-mesenchymal transition (EMT) is thought to play a crucial role in the metastatic potential of breast cancer. Growing evidence has implicated the SUMO E3 ligase PIAS1 in t
Externí odkaz:
https://doaj.org/article/73cf0300ae144afcbf3fc1ec1ee89d5b
Publikováno v:
Current Oncology, Vol 29, Iss 34, Pp 383-391 (2022)
Current Oncology
Current Oncology; Volume 29; Issue 1; Pages: 383-391
Current Oncology
Current Oncology; Volume 29; Issue 1; Pages: 383-391
Metastatic breast cancer (MBC) patient outcomes may vary according to distinct health care payers and different countries. We compared 291 Alberta (AB), Canada and 9429 US patients < 65 with de novo MBC diagnosed from 2010 through 2014. Data were ext
Autor:
Xianjun Ye, Maja H. Oktay, Xiaonan Xue, Thomas E. Rohan, Paula S. Ginter, Timothy D’Alfonso, Elizabeth N. Kornaga, Don G. Morris, David Entenberg, John S. Condeelis
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2168
Purpose: to develop several digital pathology-based machine vision algorithms for combining TMEM and MenaCalc scores and determine if a combination of these biomarkers improves the ability to predict development of distant metastasis over and above t
Autor:
John B. McIntyre, Michelle Dean, Martin Köbel, Tien Phan, Emeka K. Enwere, Elizabeth N. Kornaga, Corinne M. Doll, Prafull Ghatage, Angela Chan, Kevin Martell, Susan P. Lees-Miller
Publikováno v:
Gynecologic Oncology. 158:776-784
Purpose This study aimed to describe the prognostic value of PI3K/AKT pathway mutations in a large cohort of patients with cervical cancer. Experimental design Patients with pre-treatment archival specimens, diagnosed with FIGO stages IB-IVA cervical
Autor:
Julie Livingstone, Lincoln Stein, Cheryl Crozier, Gun Ho Jang, Cindy Q. Yao, Melanie Spears, Lauren Bathurst, Paul C. Boutros, John Douglas Mcpherson, Jane Bayani, Daniel Rea, Quang M. Trinh, Elizabeth N. Kornaga, Irina Kalatskaya, John M. S. Bartlett
Publikováno v:
JCO Precision Oncology. :1-13
PURPOSE Hormone receptor–positive breast cancer remains an ongoing therapeutic challenge, despite optimal anti-endocrine therapies. In this study, we assessed the prognostic ability of genomic signatures to identify patients at risk for recurrence
Autor:
Tammy Piper, Joema Lima, Anita Bane, Daniel F. Hayes, Chad Galderisi, Mitch Dowsett, Lisa M. McShane, Keith W. Miller, Jason Ruan, Samuel C Y Leung, Martin C. Chang, David L. Rimm, Torsten O. Nielsen, Malini Srinivasan, Yalai Bai, Shakeel Virk, John M. S. Bartlett, Hua Yang, Carsten Denkert, Michelle Dean, Judith Hugh, Richard M. Levenson, Emeka K. Enwere, Arvydas Laurinavicius, Ying Wu, Elizabeth N. Kornaga, Abhi Gholap, Anagha P. Jadhav, Liron Pantanowitz, Jane Bayani
Publikováno v:
Modern Pathology. 32:59-69
The nuclear proliferation biomarker Ki67 has potential prognostic, predictive, and monitoring roles in breast cancer. Unacceptable between-laboratory variability has limited its clinical value. The International Ki67 in Breast Cancer Working Group in
Autor:
Jms Bartlett, L.Y. Dirix, T Piper, Annette Hasenburg, Dirk G. Kieback, Carine Seynaeve, Elizabeth Mallon, Cjh Can de Velde, D.W. Rea, Paul C. Boutros, CQ Yao, Elizabeth N. Kornaga, C. Markopoulos, Jane Bayani
Publikováno v:
Cancer Research. 78:P1-06
Multiparametric assays for risk are increasingly used in the management of node-negative and node-positive hormone receptor-positive invasive breast cancer. Data from multiple sources suggests different tests may provide different risk estimates at t
Autor:
Quang M. Trinh, Gun Ho Jang, CQ Yao, Melanie Spears, Jms Bartlett, L.Y. Dirix, D.W. Rea, C. Markopoulos, Irina Kalatskaya, Julie Livingstone, Dirk G. Kieback, Elizabeth N. Kornaga, Paul C. Boutros, Lincoln Stein, Cheryl Crozier, Jane Bayani, Annette Hasenburg
Publikováno v:
Cancer Research. 78:PD4-11
Hormone receptor positive breast cancer remains an ongoing therapeutic challenge. Despite optimal anti-endocrine therapies, most breast cancer deaths follow a diagnosis of early luminal cancer. Data describing molecular events in breast cancer has ye
Autor:
Alister D'Costa, Cindy Q. Yao, Mitch Levine, M-A Quintayo, Melanie Spears, T. O. Nielsen, Chris Twelves, Jms Bartlett, Nicola Lyttle, Jane Bayani, Lois E. Shepherd, Linda Liao, KI Pritchard, Elizabeth N. Kornaga, Paul C. Boutros
Publikováno v:
Cancer Research. 78:P2-10
Background: The use of anthracycline-based chemotherapies has improved overall and disease free survival in breast cancer. However, anthracyclines can have significant toxicities including cardiotoxicity and leukemia. It is, therefore, imperative to