Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Elizabeth McIvor"'
Autor:
K.L. Powell, Erika L. Abel, Elizabeth McIvor, Stephen B. Boulware, Michael C. MacLeod, Karen M. Vasquez, John DiGiovanni, Tammy Y. Fields
Publikováno v:
Toxicology and Applied Pharmacology. 266:439-442
Mustard gas, used in chemical warfare since 1917, is a mutagenic and carcinogenic agent that produces severe dermal lesions for which there are no effective therapeutics; it is currently seen as a potential terrorist threat to civilian populations. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4dcf4f9d7db86b78b6bafad14d7218
https://doi.org/10.1016/j.taap.2012.11.020
https://doi.org/10.1016/j.taap.2012.11.020
Autor:
Tammy Y. Fields, Elizabeth McIvor, Stephen B. Boulware, Michael C. MacLeod, Erika L. Abel, Karen M. Vasquez, K. Leslie Powell
Publikováno v:
Toxicology and Applied Pharmacology. 263:203-209
Sulfur mustard [bis(2-chloroethyl)sulfide, SM] is a well-known DNA-damaging agent that has been used in chemical warfare since World War I, and is a weapon that could potentially be used in a terrorist attack on a civilian population. Dermal exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68072f15fbf0ac9ac04b4b257894058e
https://doi.org/10.1016/j.taap.2012.06.010
https://doi.org/10.1016/j.taap.2012.06.010
Publikováno v:
RNA Biology. 7:551-558
Expansion of tandem repeat sequences is responsible for more than 20 human diseases. Several cis elements and trans factors involved in repeat instability (expansion and contraction) have been identified. However no comprehensive model explaining lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808a33b21c736b5f18ec57f2482bba5b
https://doi.org/10.4161/rna.7.5.12745
https://doi.org/10.4161/rna.7.5.12745
Autor:
Jerry L. Workman, Laurence Florens, Elizabeth McIvor, Li Wang, Wenqian Li, Yue Lu, Xianjiang Lan, Tammy Calhoun-Davis, Alan J. Tackett, Samuel G. Mackintosh, Ying Zhang, Sharon Y.R. Dent, Evangelia Koutelou, Dean G. Tang, Stephanie D. Byrum, Xianghong Kuang, Kevin Lin, Boyko S. Atanassov, Michael P. Washburn, Ryan D Mohan
Publikováno v:
Molecular cell. 62(4)
Histone H2B monoubiquitination (H2Bub1) is centrally involved in gene regulation. The deubiquitination module (DUBm) of the SAGA complex is a major regulator of global H2Bub1 levels, and components of this DUBm are linked to both neurodegenerative di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee648f38d33e447d6a0fd840c3e980c6
https://pubmed.ncbi.nlm.nih.gov/27132940
https://pubmed.ncbi.nlm.nih.gov/27132940
Unstable repeat diseases (URDs) share a common mutational phenomenon of changes in the copy number of short, tandemly repeated DNA sequences. More than 20 human neurological diseases are caused by instability, predominantly, expansion of microsatelli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0808a5e97c05c33ca94a40aea27533d9
https://europepmc.org/articles/PMC4648362/
https://europepmc.org/articles/PMC4648362/
Autor:
Tammy Y. Fields, Michael C. MacLeod, John DiGiovanni, Michael Andreeff, Leslie Powell, Erika L. Abel, Jennifer D. Bubel, Elizabeth McIvor, Melissa S. Simper
Publikováno v:
Cancer Research. 71:1339-1339
Sulfur mustard (SM) is a vesicating agent that was first used in chemical warfare over 100 years ago. SM alkylates DNA and is mutagenic in various model systems. Epidemiological studies indicate that chronic exposure increases the risk of cancer in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bb33117baee098037db5e718901c5ee
https://doi.org/10.1158/1538-7445.am2011-1339
https://doi.org/10.1158/1538-7445.am2011-1339