Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elizabeth Manchen"'
Autor:
Edwin M. Posadas, Walter M. Stadler, Elizabeth K. Chung, Kristen Kasza, Theodore Karrison, Olwen Hahn, Elizabeth Manchen
Publikováno v:
American Journal of Clinical Oncology. 34:150-154
Renal cancer accounts for approximately 58,000 (4%) of new noncutaneous cancer cases and is estimated to result in approximately 13,000 deaths in the United States in 2009.1 The introduction of mTOR and vascular endothelial growth factor (VEGF) pathw
Autor:
Milica Medved, Theodore Karrison, Olwen Hahn, Cheng Yang, Myrosia T. Mitchell, Mark J. Ratain, Elizabeth Manchen, Walter M. Stadler, Gregory S. Karczmar, Emily O. Kistner
Publikováno v:
Journal of Clinical Oncology. 26:4572-4578
Purpose Sorafenib is an antiangiogenic agent with activity in renal cancer. We conducted a randomized trial to investigate dynamic contrast magnetic resonance imaging (DCE-MRI) as a pharmacodynamic biomarker. Patients and Methods Patients were random
Autor:
Elizabeth Manchen
Publikováno v:
Seminars in Oncology Nursing. 23:S11-S14
Objectives To review the treatment options for advanced or metastatic bladder cancer, including novel agents. Data Sources Research literature and clinical trial data. Conclusion Knowledge of current and novel therapies for the treatment of advanced
Publikováno v:
The journal of supportive oncology. 9(1)
One significant toxicity associated with the anticancer tyrosine kinase inhibitors (TKIs) is hand-foot skin reaction (HFSR). We provide an overview of HFSR, emphasizing experience-based prevention techniques and nursing management strategies from the
Autor:
Supriya G. Mohile, Russell Z. Szmulewitz, Edwin M. Posadas, Walter M. Stadler, Theodore Karrison, Elizabeth Manchen, Rangesh Kunnavakkam
Publikováno v:
European urology. 56(1)
Background Even in castration-resistant prostate cancer (CRPC), the androgen pathway remains biologically relevant. In preclinical models, androgen therapy for CRPC leads to growth arrest, apoptosis, and tumor shrinkage. Objective This study sought t
Autor:
Kristen Kasza, Edwin M. Posadas, Walter M. Stadler, Elizabeth K. Chung, L. Michalak, Theodore Karrison, Olwen Hahn, Elizabeth Manchen
Publikováno v:
Journal of Clinical Oncology. 27:e16072-e16072
e16072 Background: RCC is resistant to most traditional DNA and DNA repair targeted chemotherapy; although modest response rates to nucleotide analog based therapy, including GC, have been reported. Bevacizumab has activity in RCC. We thus performed
Publikováno v:
Journal of Clinical Oncology. 25:15584-15584
15584 Background: Transition to the castrate resistant state may be due, in part, to the development of a more sensitive and promiscuous androgen receptor (AR) pathway. Androgen therapy of CRPC leads to growth arrest and tumor shrinkage in preclinica