Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Elizabeth M. Troisi"'
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT Sindbis virus (SINV) infection of mice provides a model system for studying the pathogenesis of alphaviruses that infect the central nervous system (CNS) to cause encephalomyelitis. While studies of human viral infections typically focus on
Externí odkaz:
https://doaj.org/article/ad916e75113642aeadd7afeebedd49bd
Autor:
Kimberly L. W. Schultz, Victoria K. Baxter, Rebecca Glowinski, Diane E. Griffin, Elizabeth M. Troisi
Publikováno v:
Journal of General Virology
Interferon (IFN) regulatory factors (IRFs) are important determinants of the innate response to infection. We evaluated the role(s) of combined and individual IRF deficiencies in the outcome of infection of C57BL/6 mice with Sindbis virus, an alphavi
Publikováno v:
Journal of Biochemistry
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that has given rise to the devastating global pandemic. In most cases, SARS-CoV-2 infection results in the development of viral pneumonia and acute respiratory distre
Publikováno v:
Proceedings, Vol 50, Iss 78, p 78 (2020)
Sindbis virus causes age-dependent encephalomyelitis in mice. Young mice and immature neurons replicate the virus to high titers and die from infection while older mice and mature neurons restrict replication and survive infection. Studies to identif
Publikováno v:
Journal of General Virology. 99:309-320
Central nervous system (CNS) infection of C57BL/6 mice with the TE strain of Sindbis virus (SINV) provides a valuable animal model for studying the pathogenesis of alphavirus encephalomyelitis. While SINV TE inoculated intracranially causes little mo
Publikováno v:
Prion
Yeast prions are protein-based genetic elements that propagate through cell populations via cytosolic transfer from mother to daughter cell. Molecular chaperone proteins including Hsp70, the Hsp40/J-protein Sis1, and Hsp104 are required for continued
Publikováno v:
The Journal of general virology. 99(5)
Central nervous system (CNS) infection of C57BL/6 mice with the TE strain of Sindbis virus (SINV) provides a valuable animal model for studying the pathogenesis of alphavirus encephalomyelitis. While SINV TE inoculated intracranially causes little mo
Autor:
Jie Chen, Jane X. Yeh, Victoria K. Baxter, Diane E. Griffin, Elizabeth M. Troisi, Oanh Tran, Voraphoj Nilaratanakul
Publikováno v:
Journal of Virology. 92
Sindbis virus (SINV) infection of neurons in the brain and spinal cord in mice provides a model system for investigating recovery from encephalomyelitis and antibody-mediated clearance of virus from the central nervous system (CNS). To determine the
Publikováno v:
Molecular Microbiology
Summary Yeast prions require a core set of chaperone proteins including Sis1, Hsp70 and Hsp104 to generate new amyloid templates for stable propagation, yet emerging studies indicate that propagation of some prions requires additional chaperone activ
Publikováno v:
The FASEB Journal. 29