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pro vyhledávání: '"Elizabeth M. Repash"'
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Multi-drug combination therapy carries significant promise for pharmacological intervention, primarily better efficacy with less toxicity and fewer side effects. However, the field lacks methodology to assess synergistic or antagonistic interactions
Externí odkaz:
https://doaj.org/article/f4501d430b854b3b8afbcaa03d0b7357
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Multi-drug combination therapy carries significant promise for pharmacological intervention, primarily better efficacy with less toxicity and fewer side effects. However, the field lacks methodology to assess synergistic or antagonistic interactions
Publikováno v:
Free Radical Biology and Medicine. 128:S119
Small molecule Nrf2/ARE pathway activators show promise to preventchronic disease conditions, given their role in mitigating oxidative and electrophilic stress. We find that the efficacy and potency of the clinically-studied electrophilic Nrf2/ARE ac