Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elizabeth M. Morrice"'
Autor:
Alan H. Davidson, Andrew S. Tipping, Jonathon A. R. Roffey, Richard S. Todd, Christopher Lewis, Blackwell Christopher Mark, Elizabeth M. Morrice, Maxwell M. Reeve, Steven B. Launchbury
Publikováno v:
The Journal of Organic Chemistry. 57:5596-5606
The natural product dihydromevinolin, 2, and a series of structurally related 3-hydroxy-3-methylglutaryl coenzyme A (HMPG-CoA) reductase inhibitors, 3-6, have been synthesized. The key features are an intramolecular Diels-Alder reaction to form a fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f48222dc40bfbf2d545e2be3d44d2d9b
https://doi.org/10.1021/jo00047a011
https://doi.org/10.1021/jo00047a011
Autor:
Richard S. Todd, Ingrid M. White, Christopher Lewis, W.Alan Galloway, Maxwell M. Reeve, Emer M. Cunningham, Elisabeth A. Bone, Alan H. Davidson, Elizabeth M. Morrice
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:223-228
HMG-CoA reductase inhibitors structurally related to dihydromevinolin have been designed and tested. It has been shown that for high inhibitory potency these compounds must possess a methyl group at the C-7 position, but several different alkenes can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d31c3e67d57b5488202f3c234c7027b
https://doi.org/10.1016/s0960-894x(01)81069-6
https://doi.org/10.1016/s0960-894x(01)81069-6
Autor:
Steven B. Launchbury, Andrew S. Tipping, Richard S. Todd, Maxwell M. Reeve, Blackwell Christopher Mark, Elizabeth M. Morrice, Christopher Lewis, Alan H. Davidson, Jonathon A. R. Roffey
Publikováno v:
The Journal of Organic Chemistry. 57:1935-1937
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b2a1e789ee87c73e0620ba6b29ecb0a
https://doi.org/10.1021/jo00032a062
https://doi.org/10.1021/jo00032a062