Výsledky vyhledávání - "Elizabeth M. Kass"

Akademický článek

Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation

Autor: Elizabeth M. Kass, Pei Xin Lim, Hildur R. Helgadottir, Mary Ellen Moynahan, Maria Jasin

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)

Mutations in homology-directed repair genes likeBRCA2are linked to breast cancer susceptibility. Here the authors generate mice with an inducible DNA break-reporter system and see high levels of homology-directed repair in proliferative mammary tissu

Externí odkaz: https://doaj.org/article/05628ecc62f8432486b6a2626164ba2c

Zobrazit plný text záznamu

Akademický článek

Metabolic and genetic determinants of HDL metabolism and hepatic lipase activity in normolipidemic females

Autor: Elizabeth R. De Oliveira e Silva, Margaret Kong, Zhihua Han, Catherine Starr, Elizabeth M. Kass, Suh-Hang Hank Juo, David Foster, Hayes M. Dansky, Martin Merkel, Katherine Cundey, Eliot A. Brinton, Jan L. Breslow, Jonathan D. Smith

Publikováno v: Journal of Lipid Research, Vol 40, Iss 7, Pp 1211-1221 (1999)

The metabolic and genetic determinants of HDL cholesterol (HDL-C) levels and HDL turnover were studied in 36 normolipidemic female subjects on a whole-food low-fat metabolic diet. Lipid, lipoprotein, and apolipoprotein levels, lipoprotein size, and a

Externí odkaz: https://doaj.org/article/2ceabc52de4d4de38c1a326ec19e00db

Zobrazit plný text záznamu

Supplementary Figure S1 from Androgen Receptor Signaling Regulates DNA Repair in Prostate Cancers

Supplementary Figure S1 - PDF file 1194K, Gamma-H2AX foci and Comet assay normalized of LNCaP plus or minus androgen normalized to time 0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e77594a6f2297abd44d8b914566fc28
https://doi.org/10.1158/2159-8290.22529294.v1

Zobrazit plný text záznamu

Supplementary Table S2 from Androgen Receptor Signaling Regulates DNA Repair in Prostate Cancers

Supplementary Table S2 - PDF file 250K, Defining AR-regulated DNA repair genes in LNCaP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e9824254a57dbcbbfe87a6194f0ac0
https://doi.org/10.1158/2159-8290.22529276.v1

Zobrazit plný text záznamu

Supp Table 1 from Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

A list of copy number alterations, rearrangements and short variants detected by Foundation Medicine NGS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290d4db2a909f21e74c4707ffaf15b8c
https://doi.org/10.1158/2159-8290.22532014

Zobrazit plný text záznamu

Supplementary Tables and Supplementary Figures 1 through 11 from Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

Supplementary Tables, Figures and Video legends, Tables 2,3,5 and all Supplementary Figures. Supplementary Table 2. Confirmation of cis configuration of BRCA1 primary and secondary mutations in case 4 by colony PCR. Supplementary Table 3. IC50 (mirco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397e20de6afaeebadb9878c50aa24cdb
https://doi.org/10.1158/2159-8290.22532005

Zobrazit plný text záznamu

Supp Video from Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

Molecular Dynamics Modeling of WT RAD51D monofilament interaction with dsDNA.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fba9c22b5a359aa72c1e801f4e7723
https://doi.org/10.1158/2159-8290.22532008

Zobrazit plný text záznamu

Supp Table 4 from Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

Copy number estimation by SNP array in the archival tumor tissue of the patient identified to have a germline RAD51C mutation (c.577C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916a972cc1b288a8152b36cc181d3f6a
https://doi.org/10.1158/2159-8290.22532011.v1

Zobrazit plný text záznamu

ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repair

Autor: Elizabeth M. Kass, Mary Ellen Moynahan, Maria Jasin, Jayanta Chaudhuri, Wei-Feng Yen, Chun-Chin Chen, Thomas Ludwig

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 114(29)

BRCA1 is essential for homology-directed repair (HDR) of DNA double-strand breaks in part through antagonism of the nonhomologous end-joining factor 53BP1. The ATM kinase is involved in various aspects of DNA damage signaling and repair, but how ATM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6093c6640428ac77a44fed0ad522338c
https://pubmed.ncbi.nlm.nih.gov/28659469

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání