Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder

Autor: Naushaba Hasin, Lace M. Riggs, Tatyana Shekhtman, Justin Ashworth, Robert Lease, Rediet T. Oshone, Elizabeth M. Humphries, Judith A. Badner, Pippa A. Thomson, David C. Glahn, David W. Craig, Howard J. Edenberg, Elliot S. Gershon, Francis J. McMahon, John I. Nurnberger, Peter P. Zandi, John R. Kelsoe, Jared C. Roach, Todd D. Gould, Seth A. Ament

Publikováno v: Hasin, N, Riggs, L M, Shekhtman, T, Ashworth, J, Lease, R, Oshone, R T, Humphries, E M, Badner, J A, Thomson, P A, Glahn, D C, Craig, D W, Edenberg, H J, Gershon, E S, McMahon, F J, Nurnberger, J I, Zandi, P P, Kelsoe, J R, Roach, J C, Gould, T D & Ament, S A 2022, ' Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder ', Molecular Psychiatry . https://doi.org/10.1038/s41380-022-01609-4

Bipolar disorder is an often-severe mental health condition characterized by alternation between extreme mood states of mania and depression. Despite strong heritability and the recent identification of 64 common variant risk loci of small effect, pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c8a18f5ff2733bcbdb3547f088530f
https://doi.org/10.1038/s41380-022-01609-4

Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder

Autor: Naushaba, Hasin, Lace M, Riggs, Tatyana, Shekhtman, Justin, Ashworth, Robert, Lease, Rediet T, Oshone, Elizabeth M, Humphries, Judith A, Badner, Pippa A, Thomson, David C, Glahn, David W, Craig, Howard J, Edenberg, Elliot S, Gershon, Francis J, McMahon, John I, Nurnberger, Peter P, Zandi, John R, Kelsoe, Jared C, Roach, Todd D, Gould, Seth A, Ament

Publikováno v: Molecular psychiatry. 27(9)

Bipolar disorder is an often-severe mental health condition characterized by alternation between extreme mood states of mania and depression. Despite strong heritability and the recent identification of 64 common variant risk loci of small effect, pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7270af68a5276c064109092cd20c0e36
https://pubmed.ncbi.nlm.nih.gov/35546635

Discord reigns among nuclear, mitochondrial and phenotypic estimates of divergence in nine lineages of trans-Beringian birds

Autor: Elizabeth M, Humphries, Kevin, Winker

Publikováno v: Molecular ecology. 20(3)

Proposals for genetic thresholds for species delimitation assume that simple genetic data sets (e.g. mitochondrial sequence data) are correlated with speciation; i.e. such data sets accurately reflect organismal lineage divergence. We used taxonomica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::26bcb020b58c38de5d7eeb55a1e7c879
https://pubmed.ncbi.nlm.nih.gov/21199027

Multilocus phylogeography of a holarctic duck: colonization of north america from eurasia by gadwall (Anas strepera)

Autor: Jeffrey L. Peters, Igor Fefelov, Elizabeth M. Humphries, Yuri N. Zhuravlev, Kevin E. Omland

Publikováno v: Evolution; international journal of organic evolution. 62(6)

More than 100 species of birds have Holarctic distributions extending across Eurasia and North America, and many of them likely achieved these distributions by recently colonizing one continent from the other. Mitochondrial DNA (mtDNA) and five nucle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403a015d1fac4034053f6bb11c375663
https://pubmed.ncbi.nlm.nih.gov/18346221