Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elizabeth M. Henchey"'
Autor:
Kelly J Gauger, Lotfi M Bassa, Elizabeth M Henchey, Josephine Wyman, Brooke Bentley, Melissa Brown, Akihiko Shimono, Sallie S Schneider
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e78320 (2013)
The molecular mechanisms involved in the development of obesity and related complications remain unclear. Wnt signaling plays an important role in preadipocyte differentiation and adipogenesis. The expression of a Wnt antagonist, secreted frizzled re
Externí odkaz:
https://doaj.org/article/36e281cdb9be479ba04211e181ea856b
Autor:
Melissa Johnson, Sallie S. Schneider, Nagendra Yadava, D. Joseph Jerry, Elizabeth M. Henchey, Holly Mason, Nazneen Sultana, Giovanna M. Crisi, Grace Makari-Judson, Stephanie M Morin, Richard B. Arenas
Publikováno v:
Journal of Cellular Physiology. 232:2750-2765
Metabolic reprograming is a hallmark of cancer cells. However, the roles of pre-existing differences in normal cells metabolism toward cancer risk is not known. In order to assess pre-existing variations in normal cell metabolism, we have quantified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e87be34073f3eeded76c3e1b06854c98
https://doi.org/10.1002/jcp.25932
https://doi.org/10.1002/jcp.25932
Autor:
Lotfi M. Bassa, Elizabeth M. Henchey, Cody Jacobs, Sallie S. Schneider, Kelly J. Gregory, Jennifer Ser-Dolansky
Publikováno v:
Phytomedicine. 23:87-94
Background Rhodiola crenulata is a Tibetan mountainous plant, commonly used in Eastern alternative medicine. Many phytochemicals possess estrogenic activity, a critical regulator of proliferation in mammary epithelial cells. We have previously charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547239e2f919a802324df814b62ca2b3
https://doi.org/10.1016/j.phymed.2015.11.014
https://doi.org/10.1016/j.phymed.2015.11.014
Publikováno v:
Molecular Pharmaceutics
We report the in vivo efficacy, in tumor-bearing mice, of cancer prodrugs consisting of poly(methacryloyloxyethyl phosphorylcholine) (polyMPC) conjugated to doxorubicin (DOX). Our synthesis of polyMPC–DOX conjugates established prodrugs with tunabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f0be1215bc6d507b2df906add8d186
https://doi.org/10.1021/mp500009r
https://doi.org/10.1021/mp500009r
Autor:
Alejandro P. Heuck, Melissa L. Brown, Pinal Patel, Ahmed Khalil, Chul Kim, Nagendra Yadava, Lindsey M. Gouvin, Elizabeth M. Henchey
Publikováno v:
Bioenergetics : open access. 3(1)
The mitochondrial metabolism of β cells is thought to be highly specialized. Its direct comparison with other cells using isolated mitochondria is limited by the availability of islets/β cells in sufficient quantity. In this study, we have compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d435b1b06823da0ec006dd36e336369
https://pubmed.ncbi.nlm.nih.gov/25309834
https://pubmed.ncbi.nlm.nih.gov/25309834
Publikováno v:
Bioconjugate chemistry. 23(9)
We demonstrate the conjugation of the cancer drug doxorubicin (DOX) to poly(methacryloyloxyethyl phosphorylcholine) (polyMPC), linked by hydrazone groups, using (1) a one-pot ATRP/click sequence, and (2) a post-polymerization conjugation strategy. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21be9bad9bfb3ab3054a899378f9d44
https://pubmed.ncbi.nlm.nih.gov/22881479
https://pubmed.ncbi.nlm.nih.gov/22881479
Autor:
Xiangji Chen, Katrina Kratz, Debasis Samanta, Elizabeth M. Henchey, Sallie S. Schneider, Todd Emrick, Samantha McRae
Publikováno v:
Biomacromolecules. 13(7)
Novel pentafluorophenyl (PFP)-ester-functionalized phosphorylcholine (PC) polymers of different architectures were prepared and conjugated to lysozyme as a model protein. Linear and two-arm poly(2-methacryloyloxyethyl phosphorylcholine) (polyMPC) str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0973ea5b478950c9ecbb3ede3d8e4209
https://pubmed.ncbi.nlm.nih.gov/22691067
https://pubmed.ncbi.nlm.nih.gov/22691067
Publikováno v:
Molecular Cancer Research. 14:A28-A28
We have demonstrated reversible suppression of the tumor suppressor protein p53 by respiratory chain deficiency. Further, a recent study from a different group also suggests genetic inactivation of p53 by the impairments of oxidative metabolism, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e4c61c5e2b6e208daa29398f2cb826
https://doi.org/10.1158/1557-3125.metca15-a28
https://doi.org/10.1158/1557-3125.metca15-a28
Autor:
Sallie S. Schneider, Melissa L. Brown, Brooke A. Bentley, Lotfi M. Bassa, Josephine Wyman, Elizabeth M. Henchey, Kelly J. Gauger, Akihiko Shimono
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e78320 (2013)
PLoS ONE
PLoS ONE
The molecular mechanisms involved in the development of obesity and related complications remain unclear. Wnt signaling plays an important role in preadipocyte differentiation and adipogenesis. The expression of a Wnt antagonist, secreted frizzled re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f81e5d3029b62285d92d26f5b3d0149
https://doi.org/10.1371/journal.pone.0078320
https://doi.org/10.1371/journal.pone.0078320
Autor:
Sallie S. Schneider, Lotfi M. Bassa, Elizabeth M. Henchey, Akihiko Shimono, Josephine Wyman, Kelly J. Gauger, Jennifer Ser-Dolansky
Publikováno v:
Molecular Cancer
Secreted frizzled-related proteins (SFRPs) are a family of proteins that block the Wnt signaling pathway and loss of Sfrp1 expression is observed in breast cancer. The molecular mechanisms by which obesity contributes to breast tumorigenesis are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fe98ca2b65a0dbb3e4b9249e762dd9