Výsledky vyhledávání - "Elizabeth M. F. Pral"

Akademický článek

The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake.

Autor: Marcelo L Merli, Lucas Pagura, Josefina Hernández, María Julia Barisón, Elizabeth M F Pral, Ariel M Silber, Julia A Cricco

Publikováno v: PLoS Neglected Tropical Diseases, Vol 10, Iss 1, p e0004359 (2016)

Trypanosoma cruzi, the etiological agent of Chagas' disease, presents nutritional requirements for several metabolites. It requires heme for the biosynthesis of several heme-proteins involved in essential metabolic pathways like mitochondrial cytochr

Externí odkaz: https://doaj.org/article/7eab0ba16f8d4e25ba1d751bed3ca43f

Zobrazit plný text záznamu

The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection

Autor: Flávia Silva Damasceno, Agustino Hernandez, Raphael Souza Pavani, Marcell Crispim, Ariel Mariano Silber, Alexandre S. Moura, Mauro Cortez, Maria Carolina Elias, Elizabeth M. F. Pral, María Julia Barisón, Ismael P. Sauter

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006170 (2018)

Trypanosoma cruzi, the etiological agent of Chagas disease, consumes glucose and amino acids depending on the environmental availability of each nutrient during its complex life cycle. For example, amino acids are the major energy and carbon sources

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af18d2fa932349e1de08b5071be3b3ad

Zobrazit plný text záznamu

The Uptake of GABA in Trypanosoma cruzi

Autor: Elizabeth M. F. Pral, Brian S. Mantilla, Ariel Mariano Silber, Robert Leonardo Galvez Rojas, Il-Young Ahn, Celso Sant'Anna

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Gamma aminobutyric acid (GABA) is widely known as a neurotransmitter and signal transduction molecule found in vertebrates, plants, and some protozoan organisms. However, the presence of GABA and its role in trypanosomatids is unknown. Here, we repor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eadd1bc280fa2e984d391ea0857ba68
https://doi.org/10.1111/jeu.12219

Zobrazit plný text záznamu

Metabolomic profiling reveals a finely tuned, starvation-induced metabolic switch in Trypanosoma cruzi epimastigotes

Autor: Letícia Marchese, Cristina Nowicki, Brian S. Mantilla, Elizabeth M. F. Pral, Ariel Mariano Silber, Emilio F. Merino, Ludmila Nakamura Rapado, Maria B. Cassera, María Julia Barisón

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Journal of biological chemistry, 2017, Vol.292(21), pp.8964-8977 [Peer Reviewed Journal]

Trypanosoma cruzi, the etiological agent of Chagas disease, is a protozoan parasite with a complex life cycle involving a triatomine insect and mammals. Throughout its life cycle, the T. cruzi parasite faces several alternating events of cell divisio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6788f33e36a3ba179dcb435ceda21002
https://europepmc.org/articles/PMC5448128/

Zobrazit plný text záznamu

An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells

Autor: Miroslav Bajić, Flávia Silva Damasceno, Richard M. B. M. Girard, Elizabeth M. F. Pral, Marcell Crispim, Ariel Mariano Silber, Marcelo Santos da Silva, Ivana Stolić, Maria Carolina Elias

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Trypanosoma cruzi is the etiological agent of Chagas disease, affecting approximately 10 million people in the Americas and with some 40 million people at risk. The objective of this study was to evaluate the anti- T. cruzi activity of three new diam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a882e4ae0173e86db5d44829d95ffb5
https://europepmc.org/articles/PMC5038236/

Zobrazit plný text záznamu

Cysteine proteases of Trypanosoma (Megatrypanum) theileri: Cathepsin L-like gene sequences as targets for phylogenetic analysis, genotyping diagnosis

Autor: Jael Soares Batista, Paola A. Ortiz, Adriana C. Rodrigues, Antonio Humberto Hamad Minervino, Silvia C. Alfieri, Herakles A. Garcia, Fernando Paiva, Franjo Martinković, A. P. Cortez, Elizabeth M. F. Pral, Marta Maria Geraldes Teixeira, Marta Campaner

Publikováno v: Parasitology International. 59:318-325

Although Trypanosoma theileri and allied trypanosomes are the most widespread trypanosomes in bovids little is known about proteolytic enzymes in these species. We have characterized genes encoding for cathepsin L-like (CATL) cysteine proteases from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceef442d316586e5d6013f422ea68000
https://doi.org/10.1016/j.parint.2010.03.002

Zobrazit plný text záznamu

Genes of cathepsin L-like proteases in Trypanosoma rangeli isolates: Markers for diagnosis, genotyping and phylogenetic relationships

Autor: Elizabeth M. F. Pral, F. Maia da Silva, Luciana Lima, Marta Maria Geraldes Teixeira, Paola A. Ortiz, A. P. Cortez, Silvia C. Alfieri, Marta Campaner

Publikováno v: Acta Tropica. 112:249-259

We have sequenced genes encoding cathepsin L-like (CatL-like) cysteine proteases from isolates of Trypanosoma rangeli from humans, wild mammals and Rhodnius species of Central and South America. Phylogenetic trees of sequences encoding mature CatL-li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f2a32d1e76faa4b2c19832af771136
https://doi.org/10.1016/j.actatropica.2009.07.036

Zobrazit plný text záznamu

Bioactivity of Flavonoids Isolated from Lychnophora markgravii against Leishmania amazonensis Amastigotes

Autor: Fabiana Terezinha Sartori, Silvia C. Alfieri, Marcos José Salvador, Walter Vichnewski, Elizabeth M. F. Pral, Ana Claudia Barrachia Costa Sacilotto

Publikováno v: Zeitschrift für Naturforschung C. 64:509-512

The bioactivity of the flavonoids pinostrobin (1), pinocembrin (2), tectochrysin (3), galangin 3-methyl ether (4), and tiliroside (5) isolated from Lychnophora markgravii aerial parts was investigated in vitro against amastigote stages of Leishmania

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6f2b88c6a66d2388381cd7e6f4e286
https://doi.org/10.1515/znc-2009-7-807

Zobrazit plný text záznamu

Role of Δ1-pyrroline-5-carboxylate dehydrogenase supports mitochondrial metabolism and host-cell invasion of trypanosoma cruzi

Autor: Patricio Fernández-Silva, Elizabeth M. F. Pral, Otavio Henrique Thiemann, Ariel Mariano Silber, Daiana E. Martil, Brian S. Mantilla, Erick Leite Bastos, Lisvane Silva Paes

Publikováno v: Journal of biological chemistry, 2015, Vol.290(12), pp.7767-7790 [Peer Reviewed Journal]
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Proline is crucial for energizing critical events throughout the life cycle of Trypanosoma cruzi, the etiological agent of Chagas disease. The proline breakdown pathway consists of two oxidation steps, both of which produce reducing equivalents as fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6666957f5baa20e133873d7fc5b4727a
http://dro.dur.ac.uk/29097/

Zobrazit plný text záznamu

Biological activities and chemical composition of crude extracts from Chresta exsucca

Autor: Silvia C. Alfieri, Sérgio de Albuquerque, Elizabeth M. F. Pral, Marcos José Salvador, Diones Aparecida Dias, Izabel Yoko Ito, Elisandra Cristina Schinor, José Carlos Tomaz

Publikováno v: Revista Brasileira de Ciências Farmacêuticas; Vol. 42 Núm. 1 (2006); 83-90
Revista Brasileira de Ciências Farmacêuticas; v. 42 n. 1 (2006); 83-90
Revista Brasileira de Ciências Farmacêuticas; Vol. 42 No. 1 (2006); 83-90
RBCF. Revista Brasileira de Ciências Farmacêuticas
Universidade de São Paulo (USP)
instacron:USP

As atividades tripanocida, leishmanicida, antibacteriana e antifungica dos extratos brutos de Chresta exsucca foram investigadas. Formas tripomastigotas do Trypanosoma cruzi, formas amastigotas de Leishmania amazonensis e vinte cepas de microrganismo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1959a619ee738180eda12d4b8c30619
https://doi.org/10.1590/s1516-93322006000100009

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání