Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Elizabeth M. Diessner"'
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 328 (2023)
Understanding the molecular adaptations of organisms to extreme environments requires a comparative analysis of protein structure, function, and dynamics across species found in different environmental conditions. Computational studies can be particu
Externí odkaz:
https://doaj.org/article/9d15f349fb6b41ad8a4ccc3d6622f20a
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1788 (2021)
Coarse-graining is a powerful tool for extending the reach of dynamic models of proteins and other biological macromolecules. Topological coarse-graining, in which biomolecules or sets thereof are represented via graph structures, is a particularly u
Externí odkaz:
https://doaj.org/article/365b927f285646e79a284277e3bff8a2
Autor:
Elizabeth M. Diessner, Gemma R. Takahashi, Thomas J. Cross, Rachel W. Martin, Carter T. Butts
Publikováno v:
Biochemistry. 62:747-758
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10d0dc6e82bcb61ef9c050c78ae4d3c3
https://doi.org/10.1021/acs.biochem.2c00479
https://doi.org/10.1021/acs.biochem.2c00479
Publikováno v:
The Journal of Physical Chemistry B. 127:685-697
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b907102aa54291d90bf695cd8ce2576
https://doi.org/10.1021/acs.jpcb.2c07672
https://doi.org/10.1021/acs.jpcb.2c07672
Autor:
Jessica I. Kelz, Gemma R. Takahashi, Fatemeh Safizadeh, Vesta Farahmand, Marquise G. Crosby, Jose L. Uribe, Suhn H. Kim, Marc A. Sprague-Piercy, Elizabeth M. Diessner, Brenna Norton-Baker, Steven M. Damo, Rachel W. Martin, Pavan Kadandale
Publikováno v:
The Biophysicist. 3:49-63
A major challenge for science educators is teaching foundational concepts while introducing their students to current research. Here we describe an active learning module developed to teach protein structure fundamentals while supporting ongoing rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bf83f54ca0b24e3f4984314ee3c86e9
https://doi.org/10.35459/tbp.2021.000209
https://doi.org/10.35459/tbp.2021.000209
Publikováno v:
Biophysical Journal. 122:206a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40a886bc218b17038d540071bc817850
https://doi.org/10.1016/j.bpj.2022.11.1240
https://doi.org/10.1016/j.bpj.2022.11.1240
Autor:
Rachel W. Martin, Vesta Farahmand, Marquise G. Crosby, Pavan Kadandale, Jessica I. Kelz, Fatemeh Safizadeh, Suhn H. Kim, Steven M. Damo, Gemma R. Takahashi, Marc A. Sprague-Piercy, Jose Luis Uribe, Elizabeth M. Diessner, Brenna Norton-Baker
A major challenge for science educators is teaching foundational concepts while introducing their students to current research. Here we describe an active learning module developed to teach protein structure fundamentals while supporting ongoing rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bb119be38cea8256771d759500494c5
https://doi.org/10.1101/2021.08.19.456875
https://doi.org/10.1101/2021.08.19.456875
Autor:
Jose L. Uribe, Jessica I. Kelz, Gemma R. Takahashi, Fatemeh Safizadeh, Vesta Farahmand, Marquise G. Crosby, Suhn H. Kim, Marc A. Sprague-Piercy, Elizabeth M. Diessner, Brenna Norton-Baker, Steven M. Damo, Rachel W. Martin, Pavan Kadandale
Publikováno v:
Biophysical Journal. 121:545a-546a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21cbca9cf498846c95c8e51dc2da4f46
https://doi.org/10.1016/j.bpj.2021.11.2876
https://doi.org/10.1016/j.bpj.2021.11.2876
Autor:
Michael A. Morris, Chelsea Marie T. Parrocha, Carter T. Butts, Maj Krumberger, Gretchen Guaglianone, Adam G. Kreutzer, James S. Nowick, Elizabeth M. Diessner
Publikováno v:
European Journal of Medicinal Chemistry
This paper presents the design and study of a first-in-class cyclic peptide inhibitor against the SARS-CoV-2 main protease (Mpro). The cyclic peptide inhibitor is designed to mimic the conformation of a substrate at a C-terminal autolytic cleavage si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8822a5694e3b277154fc0e02b518174a
https://pubmed.ncbi.nlm.nih.gov/34023738
https://pubmed.ncbi.nlm.nih.gov/34023738
Autor:
Rachel W. Martin, Elizabeth M. Diessner, Marquise G. Crosby, Vesta Farahmand, Carter T. Butts, Thomas J Cross, Shannon Zhuang, Gemma R. Takahashi
Publikováno v:
Biochemistry
bioRxiv
bioRxiv
The SARS-CoV-2 main protease (Mpro) is essential to viral replication and cleaves highly specific substrate sequences, making it an obvious target for inhibitor design. However, as for any virus, SARS-CoV-2 is subject to constant selection pressure,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51015b60d69437e873c34c3a1ee93c40
http://europepmc.org/articles/PMC7518256
http://europepmc.org/articles/PMC7518256