Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Elizabeth M. Denholm"'
Autor:
Robert A. Quaife, Lewis J. Rubin, Frank W. Smart, Norbert F. Voelkel, Yuichiro J. Suzuki, Michael D. McGoon, Elizabeth M. Denholm, Daniel R. Meldrum, Robyn J. Barst, Dorothy B. Gail, Carlin S. Long, Mark T. Gladwin, Jocelyn Dupuis, Leslie A. Leinwand
Publikováno v:
Circulation. 114:1883-1891
Knowledge about the role of the right ventricle in health and disease historically has lagged behind that of the left ventricle. Less muscular, restricted in its role to pumping blood through a single organ, and less frequently or obviously involved
Publikováno v:
European Journal of Pharmacology. 400:145-153
In the current study, a glycosaminoglycan lyase, chondroitinase B, was used to study the role of dermatan sulfate proteoglycans on human dermal fibroblast proliferation. Pretreatment with chondroitinase B significantly decreased fibroblast proliferat
Publikováno v:
Journal of Biological Chemistry. 271:17779-17784
Recent studies indicate potential roles of monocyte chemotactic protein-1 (MCP-1) in recruitment of monocytes to sites of inflammation. However, their increased expression does not always correlate with monocyte influx, suggesting other possible biol
Autor:
Sem H. Phan, Elizabeth M. Denholm
Publikováno v:
Journal of Leukocyte Biology. 48:519-523
Previous work has demonstrated that bleomycin can directly stimulate alveolar macrophage secretion of fibroblast growth factors and monocyte chemotactic factors. In this study, rat alveolar macrophages obtained by bronchoalveolar lavage were examined
Publikováno v:
European journal of pharmacology. 416(3)
In the current study, two specific glycosaminoglycan lyases, chondroitinase AC and chondroitinase B, were utilized to examine the roles of chondroitin sulfates and dermatan sulfate in tumor metastasis and angiogenesis. Melanoma cells (SK-MEL) or endo
Publikováno v:
Translational Research. 151:57-58
Clearly, a need exists to translate more quickly myriad discoveries in biomedical research into more effective applications relevant to human health and disease. In recognition of the need for a more efficient and coordinated translational effort, th
Autor:
Yong-Qing Lin, Linh Nguyen, Jean-Pierre Moreau, Clark Bennett, Achim Recktenwald, Elizabeth M. Denholm, Suzanne Ranger, Paul J. Silver, Susan Baker, Denis deBlois
Publikováno v:
European journal of pharmacology. 351(1)
Heparinase III degrades heparan sulfate proteoglycans, which are co-receptors for growth factors that stimulate arterial proliferation. We assessed the ability of locally-delivered heparinase III to limit medial vascular smooth muscle cell proliferat
Publikováno v:
Cytokine. 7(5)
Human monocytic THP-1 cells were differentiated to macrophages by incubation with 1.0 microM phorbol myristate acetate (PMA) for 1 to 18 h; cells were then assayed for the ability to migrate to MCP-1. In comparison to undifferentiated monocytes, the
Publikováno v:
Cytometry. 19(4)
Fluorescent probes have been utilized to label leukocytes for both in vivo and in vitro studies of cell migration; however, the effects of such probes on migration have not been determined. The aim of this study was to examine the effects of two comm
Publikováno v:
Federal Register (National Archives & Records Service, Office of the Federal Register). 4/4/2011, Vol. 76 Issue 64, p18347-18630. 284p. 15 Charts.