Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Elizabeth M Burton"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Immune checkpoint inhibitors (ICIs) have produced significant survival benefit across many tumor types. However, immune-related adverse events are common including autoimmune responses against different endocrine organs. Here, a case of IC
Externí odkaz:
https://doaj.org/article/dc4e27131e424ebbb478156dbbdd5e6c
Autor:
Miles C. Andrews, Junna Oba, Chang-Jiun Wu, Haifeng Zhu, Tatiana Karpinets, Caitlin A. Creasy, Marie-Andrée Forget, Xiaoxing Yu, Xingzhi Song, Xizeng Mao, A. Gordon Robertson, Gabriele Romano, Peng Li, Elizabeth M. Burton, Yiling Lu, Robert Szczepaniak Sloane, Khalida M. Wani, Kunal Rai, Alexander J. Lazar, Lauren E. Haydu, Matias A. Bustos, Jianjun Shen, Yueping Chen, Margaret B. Morgan, Jennifer A. Wargo, Lawrence N. Kwong, Cara L. Haymaker, Elizabeth A. Grimm, Patrick Hwu, Dave S. B. Hoon, Jianhua Zhang, Jeffrey E. Gershenwald, Michael A. Davies, P. Andrew Futreal, Chantale Bernatchez, Scott E. Woodman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The regulation of the distinct intrinsic phenotypic states in melanoma remain poorly characterised. Here, multi-omics analysis for a panel of 68 early passage melanoma cell lines reveals that cancer cell intrinsic transcriptomic programs are associat
Externí odkaz:
https://doaj.org/article/96b59787498043a5a256fe86f8315695
Autor:
Elizabeth M. Burton, Rodabe N. Amaria, Tina Cascone, Myriam Chalabi, Neil D. Gross, Elizabeth A. Mittendorf, Richard A. Scolyer, Padmanee Sharma, Paolo A. Ascierto
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract After the success of immunotherapy in the treatment of advanced metastatic cancer, further evaluation in earlier settings, including high-risk, surgically-resectable disease is underway. Potential benefits of a neoadjuvant immunotherapeutic
Externí odkaz:
https://doaj.org/article/cfb90c8c178541e79522621d06de02ab
Autor:
Rajasekharan Somasundaram, Thomas Connelly, Robin Choi, Hyeree Choi, Anastasia Samarkina, Ling Li, Elizabeth Gregorio, Yeqing Chen, Rohit Thakur, Mohamed Abdel-Mohsen, Marilda Beqiri, Meaghan Kiernan, Michela Perego, Fang Wang, Min Xiao, Patricia Brafford, Xue Yang, Xiaowei Xu, Anthony Secreto, Gwenn Danet-Desnoyers, Daniel Traum, Klaus H. Kaestner, Alexander C. Huang, Denitsa Hristova, Joshua Wang, Mizuho Fukunaga-Kalabis, Clemens Krepler, Fang Ping-Chen, Xiangyang Zhou, Alexis Gutierrez, Vito W. Rebecca, Prashanthi Vonteddu, Farokh Dotiwala, Shashi Bala, Sonali Majumdar, Harsh Dweep, Jayamanna Wickramasinghe, Andrew V. Kossenkov, Jorge Reyes-Arbujas, Kenisha Santiago, Tran Nguyen, Johannes Griss, Frederick Keeney, James Hayden, Brian J. Gavin, David Weiner, Luis J. Montaner, Qin Liu, Lukas Peiffer, Jürgen Becker, Elizabeth M. Burton, Michael A. Davies, Michael T. Tetzlaff, Kar Muthumani, Jennifer A. Wargo, Dmitry Gabrilovich, Meenhard Herlyn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Immune checkpoint therapies (ICT) are promising for treating various cancers, but response rates vary. Here the authors show, in mouse models, that tumor-infiltrating mast cells colocalize with regulatory T cells, coincide with local reduction of MHC
Externí odkaz:
https://doaj.org/article/1dbc726f512b49e4900c71d53883f0cc
Autor:
Akash Mitra, Miles C. Andrews, Whijae Roh, Marianna Petaccia De Macedo, Courtney W. Hudgens, Fernando Carapeto, Shailbala Singh, Alexandre Reuben, Feng Wang, Xizeng Mao, Xingzhi Song, Khalida Wani, Samantha Tippen, Kwok-Shing Ng, Aislyn Schalck, Donald A. Sakellariou-Thompson, Eveline Chen, Sangeetha M. Reddy, Christine N. Spencer, Diana Wiesnoski, Latasha D. Little, Curtis Gumbs, Zachary A. Cooper, Elizabeth M. Burton, Patrick Hwu, Michael A. Davies, Jianhua Zhang, Chantale Bernatchez, Nicholas Navin, Padmanee Sharma, James P. Allison, Jennifer A. Wargo, Cassian Yee, Michael T. Tetzlaff, Wen-Jen Hwu, Alexander J. Lazar, P. Andrew Futreal
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Immunotherapies now dominate the treatment landscape for melanoma, but why they only work in a subset of patients remains unclear. Here, the authors perform an immunogenomic analysis on 67 intratumor sub-regions of a PD-1 inhibitor resistant melanoma
Externí odkaz:
https://doaj.org/article/97e9b4c4c8f048e9a752f694b5bd17ef
Autor:
Dereddi Raja Reddy, John A. Cuenca, Joshua Botdorf, Mayoora Muthu, Ankit Hanmandlu, Robert Wegner, John Crommett, Cristina Gutierrez, Nisha Rathi, Bilja Sajith, Mark Knafl, Hussein A. Abbas, Scott E. Woodman, Joseph L. Nates, Ashley Aaroe, Thomas A. Aloia, Lee Andrews, Kiran K. Badami, Janna A. Baganz, Pratibha Bajwa, Lori R. Baker, Gregory R. Barbosa, Hannah C. Beird, Matt Bourgeois, Kristy Brock, Elizabeth M. Burton, Juan Cata, Caroline Chung, Michael Cutherell, Pierre B. Cyr, Bouthaina Dabaja, Hiba Dagher, Kevin M. Daniels, Mary Domask, Giulio Draetta, Sarah Fisher, Katy Elizabeth French, Andrew Futreal, Maria Gaeta, Christopher Gibbons, Myrna Godoy, Drew Goldstein, Jillian Gunther, Cristhiam Hernandez, Kate Hutcheson, David Jaffray, Jeff Jin, Teny Matthew John, Trey Kell, Anai Kothari, Rayson C. Kwan, J. Jack Lee, Yue Liao, Jennifer Litton, Alex Liu, Kevin W. McEnery, Mary McGuire, Tego Musunuru, Craig S. Owen, Priyadharshini Padmakumar, Melody Page, Nicholas Palaskas, Jay J. Patel, Sabitha Prabhakaran, Vinod Ravi, Ludivine Russell, Paul A. Scheet, Stephanie Schmidt, Kenna R. Shaw, Sanjay Shete, Daniel P. Shoenthal, Lessley J. Stoltenberg, Ishwaria Subbiah, Chuck Suitor, Hussein Tawbi, Phillip Thompson, Anastasia Turin, Samir Unni, Benju Vicknamparampil, Max C. Weber, John Weinstein, Zoe Williams, Mark C. Wozny, Carol Wu, Jia Wu, James C. Yao, Chingyi Young, Emily Yu, Steven Zatorski
Publikováno v:
Mayo Clinic Proceedings. 98:451-457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0e4285ed56e25e2fcce40cf942510c3
https://doi.org/10.1016/j.mayocp.2022.12.008
https://doi.org/10.1016/j.mayocp.2022.12.008
Autor:
Alexander C J, van Akkooi, Tina J, Hieken, Elizabeth M, Burton, Charlotte, Ariyan, Paolo A, Ascierto, Salvatore V M A, Asero, Christian U, Blank, Matthew S, Block, Genevieve M, Boland, Corrado, Caraco, Sydney, Chng, B Scott, Davidson, Joao Pedreira, Duprat Neto, Mark B, Faries, Jeffrey E, Gershenwald, Dirk J, Grunhagen, David E, Gyorki, Dale, Han, Andrew J, Hayes, Winan J, van Houdt, Giorgos C, Karakousis, Willem M C, Klop, Georgina V, Long, Michael C, Lowe, Alexander M, Menzies, Roger, Olofsson Bagge, Thomas E, Pennington, Piotr, Rutkowski, Robyn P M, Saw, Richard A, Scolyer, Kerwin F, Shannon, Vernon K, Sondak, Hussein, Tawbi, Alessandro A E, Testori, Mike T, Tetzlaff, John F, Thompson, Jonathan S, Zager, Charlotte L, Zuur, Jennifer A, Wargo, Andrew J, Spillane, Merrick I, Ross
Publikováno v:
Annals of Surgical Oncology, 29(6), 3694-3708. Springer New York
Exciting advances in melanoma systemic therapies have presented the opportunity for surgical oncologists and their multidisciplinary colleagues to test the neoadjuvant systemic treatment approach in high-risk, resectable metastatic melanomas. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e872abd5d1a96ea257aff63c3b671c
https://doi.org/10.1245/s10434-021-11236-y
https://doi.org/10.1245/s10434-021-11236-y
Autor:
Jennifer L. McQuade, Yana G. Najjar, Greg M. Delgoffe, Michael A. Davies, Weiyi Peng, James S. Wilmott, Jianhua Zhang, Andrew Futreal, Han Liang, Ralph J. DeBerardinis, John M. Kirkwood, Jennifer A. Wargo, Dirk Schadendorf, Alexander J. Lazar, Michael T. Tetzlaff, Richard A. Scolyer, Georgina V. Long, Jeffrey E. Gershenwald, Nadim Ajami, Patrick Hwu, Jeffrey E. Lee, John F. Thompson, Khalida M. Wani, Jian Wang, Grant M. Fischer, Renato Guerrieri, Y.N. Vashisht Gopal, Scott E. Woodman, Nagireddy Putluri, Chantale Bernatchez, Julie M. Simon, Jared Malke, Elizabeth M. Burton, Vancheswaran Gopalakrishnan, M.A. Wadud Khan, Lauren E. Haydu, Theodore Nowicki, Courtney W. Hudgens, Carrie R. Daniel, Alexander M. Menzies, Christine N. Spencer, Yan Zang, Camelia Quek, Tuba N. Gide, Aditya K. Mishra, Xiaogang Wu, Jun Li, Mingchu Xu, Ryan C. Augustin, Dayana B. Rivadeneira, Ashley V. Menk, Andrew W. Hahn
Supplementary Table 1: Baseline characteristics for patients included in the integrated gene set enrichment analysis (Figure 2-3) by cohort; Supplementary Table 6: The most frequent somatic alterations (alts) in patients with regionally metastatic me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e0d286392da9de64a5ae2a2632417b
https://doi.org/10.1158/1078-0432.22488729.v1
https://doi.org/10.1158/1078-0432.22488729.v1
Autor:
Jennifer L. McQuade, Yana G. Najjar, Greg M. Delgoffe, Michael A. Davies, Weiyi Peng, James S. Wilmott, Jianhua Zhang, Andrew Futreal, Han Liang, Ralph J. DeBerardinis, John M. Kirkwood, Jennifer A. Wargo, Dirk Schadendorf, Alexander J. Lazar, Michael T. Tetzlaff, Richard A. Scolyer, Georgina V. Long, Jeffrey E. Gershenwald, Nadim Ajami, Patrick Hwu, Jeffrey E. Lee, John F. Thompson, Khalida M. Wani, Jian Wang, Grant M. Fischer, Renato Guerrieri, Y.N. Vashisht Gopal, Scott E. Woodman, Nagireddy Putluri, Chantale Bernatchez, Julie M. Simon, Jared Malke, Elizabeth M. Burton, Vancheswaran Gopalakrishnan, M.A. Wadud Khan, Lauren E. Haydu, Theodore Nowicki, Courtney W. Hudgens, Carrie R. Daniel, Alexander M. Menzies, Christine N. Spencer, Yan Zang, Camelia Quek, Tuba N. Gide, Aditya K. Mishra, Xiaogang Wu, Jun Li, Mingchu Xu, Ryan C. Augustin, Dayana B. Rivadeneira, Ashley V. Menk, Andrew W. Hahn
Integrated gene set enrichment analysis by body mass index (BMI) with correction for S phase. This figure presents a dotplot of genes differentially up- or downregulated in OW/OB patients versus NL BMI patients. Red indicates upregulation in OW/OB ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e1234608e81d53bb5fc98e6222af62
https://doi.org/10.1158/1078-0432.22488771.v1
https://doi.org/10.1158/1078-0432.22488771.v1
Autor:
Jennifer L. McQuade, Yana G. Najjar, Greg M. Delgoffe, Michael A. Davies, Weiyi Peng, James S. Wilmott, Jianhua Zhang, Andrew Futreal, Han Liang, Ralph J. DeBerardinis, John M. Kirkwood, Jennifer A. Wargo, Dirk Schadendorf, Alexander J. Lazar, Michael T. Tetzlaff, Richard A. Scolyer, Georgina V. Long, Jeffrey E. Gershenwald, Nadim Ajami, Patrick Hwu, Jeffrey E. Lee, John F. Thompson, Khalida M. Wani, Jian Wang, Grant M. Fischer, Renato Guerrieri, Y.N. Vashisht Gopal, Scott E. Woodman, Nagireddy Putluri, Chantale Bernatchez, Julie M. Simon, Jared Malke, Elizabeth M. Burton, Vancheswaran Gopalakrishnan, M.A. Wadud Khan, Lauren E. Haydu, Theodore Nowicki, Courtney W. Hudgens, Carrie R. Daniel, Alexander M. Menzies, Christine N. Spencer, Yan Zang, Camelia Quek, Tuba N. Gide, Aditya K. Mishra, Xiaogang Wu, Jun Li, Mingchu Xu, Ryan C. Augustin, Dayana B. Rivadeneira, Ashley V. Menk, Andrew W. Hahn
Differential gene expression analysis for each subgroup.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca30a8a74ec42000707d150324a618be
https://doi.org/10.1158/1078-0432.22488738
https://doi.org/10.1158/1078-0432.22488738