Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Elizabeth M Black"'
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Akademický článek
ATR protects centromere identity by promoting DAXX association with PML nuclear bodies
Autor: Isabelle Trier, Elizabeth M. Black, Yoon Ki Joo, Lilian Kabeche
Publikováno v: Cell Reports, Vol 42, Iss 5, Pp 112495- (2023)
Summary: Centromere protein A (CENP-A) defines centromere identity and nucleates kinetochore formation for mitotic chromosome segregation. Here, we show that ataxia telangiectasia and Rad3-related (ATR) kinase, a master regulator of the DNA damage re
Externí odkaz: https://doaj.org/article/8a50cbb027794ef0918b632cf7919492
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2
Keeping RelApse in Chk: molecular mechanisms of Chk1 inhibitor resistance in lymphoma
Autor: Elizabeth M. Black, Yoon Ki Joo, Lilian Kabeche
Publikováno v: Biochemical Journal. 479:2345-2349
Chk1 is a member of the DNA damage response pathway, whose loss leads to replication stress and genome instability. Because of its protective role against lethal levels of DNA replication stress, Chk1 has been studied as a valuable and intriguing tar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4777747dc09dee359d247a84dba9c0e9
https://doi.org/10.1042/bcj20220461
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3
Repetitive Fragile Sites: Centromere Satellite DNA as a Source of Genome Instability in Human Diseases
Autor: Elizabeth M. Black, Simona Giunta
Publikováno v: Genes, Vol 9, Iss 12, p 615 (2018)
Genes
Maintenance of an intact genome is essential for cellular and organismal homeostasis. The centromere is a specialized chromosomal locus required for faithful genome inheritance at each round of cell division. Human centromeres are composed of large t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8fd650145ce06afc78b5c7a4b6e4bb
https://www.mdpi.com/2073-4425/9/12/615
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4
A rapid RT-PCR method to differentiate six established genotypes of rabies and rabies-related viruses using TaqMan™ technology
Autor: Lorraine M. McElhinney, Elizabeth M Black, Paul R. Heaton, Jemma Smith, J.Paul Lowings
Publikováno v: Journal of Virological Methods
A rapid and sensitive reverse transcriptase-polymerase chain reaction (RT-PCR) assay incorporating TaqMan™ probes has been developed that can distinguish among the six established rabies and rabies-related virus genotypes. TaqMan™ probes were des
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751cd7930e5fc964d7332d3aba133745
http://europepmc.org/articles/PMC7119615
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5
Assessment of template quality by the incorporation of an internal control into a RT-PCR for the detection of rabies and rabies-related viruses
Autor: Lorraine M. McElhinney, J.Paul Lowings, Jemma Smith, Elizabeth M Black, Paul R. Heaton
Publikováno v: Journal of virological methods. 84(2)
A method is described to assess RNA template quality by the incorporation of a ribosomal RNA (rRNA) internal (in tube) control into a standard rabies and rabies-related virus specific RT-PCR. Specific virus and rRNA templates were co-amplified in a d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0628ccf4f0c301de859db28147b47fa
https://pubmed.ncbi.nlm.nih.gov/10680960
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