Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Elizabeth M, Fugate"'
Autor:
Farrah N. Brown, Eri Iwasawa, Crystal Shula, Elizabeth M. Fugate, Diana M. Lindquist, Francesco T. Mangano, June Goto
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Neonatal hydrocephalus is a congenital abnormality resulting in an inflammatory response and microglial cell activation both clinically and in animal models. Previously, we reported a mutation in a motile cilia gene, Ccdc39 that d
Externí odkaz:
https://doaj.org/article/47e6231a38094abf9e1435ce3797e875
Autor:
Alicia Bedolla, Aleksandr Taranov, Fucheng Luo, Jiapeng Wang, Flavia Turcato, Elizabeth M. Fugate, Nigel H. Greig, Diana M. Lindquist, Steven A. Crone, June Goto, Yu Luo
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Two recently developed novel rodent models have been reported to ablate microglia, either by genetically targeting microglia (via Cx3cr1-creER: iDTR + Dtx) or through pharmacologically targeting the CSF1R receptor with its inhibit
Externí odkaz:
https://doaj.org/article/9e9169c511894de18604fa32ac1bba9c
Autor:
Hong-Ru Chen, Xiaohui Zhang-Brotzge, Yury M. Morozov, Yuancheng Li, Siming Wang, Helen Heju Zhang, Irena S. Kuan, Elizabeth M. Fugate, Hui Mao, Yu-Yo Sun, Pasko Rakic, Diana M. Lindquist, Ton DeGrauw, Chia-Yi Kuan
Publikováno v:
JCI Insight, Vol 6, Iss 17 (2021)
The creatine transporter (CrT) maintains brain creatine (Cr) levels, but the effects of its deficiency on energetics adaptation under stress remain unclear. There are also no effective treatments for CrT deficiency, the second most common cause of X-
Externí odkaz:
https://doaj.org/article/927d1c1aefe84c5fbf121667460aa626
Autor:
A. Scott Emmert, Eri Iwasawa, Crystal Shula, Preston Schultz, Diana Lindquist, R. Scott Dunn, Elizabeth M. Fugate, Yueh-Chiang Hu, Francesco T. Mangano, June Goto
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 11 (2019)
Neonatal hydrocephalus affects about one child per 1000 births and is a major congenital brain abnormality. We previously discovered a gene mutation within the coiled-coil domain-containing 39 (Ccdc39) gene, which causes the progressive hydrocephalus
Externí odkaz:
https://doaj.org/article/820c6ed3f79b41dfa9bea4f4ba5e2192
Autor:
Jason C. Woods, Alexander S. Cochran, Jinbang Guo, Elizabeth M. Fugate, Brian M. Varisco, Zackary I. Cleveland, Matthew S. Freeman, James D. Quirk, Peter Niedbalski, Cory B Davis, Jerry Dahlke
Publikováno v:
Magnetic Resonance in Medicine. 85:2160-2173
Purpose Diffusion and lung morphometry imaging using hyperpolarized gases are promising tools to quantify pulmonary microstructure noninvasively in humans and in animal models. These techniques assume the motion encoded is exclusively diffusive gas d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78b24c54564430f55d5e53ee7bfbd722
https://doi.org/10.1002/mrm.28539
https://doi.org/10.1002/mrm.28539
Autor:
Marchelle R. Smucker, P. Ellen Grant, Rui Cao, Diana M. Lindquist, Yiming Wang, Hong-Ru Chen, Yu-Yo Sun, Yi-Min Kuo, Song Hu, Chia-Yi Kuan, Naidi Sun, Elizabeth M. Fugate
Hypothermia is the best available therapy for neonatal hypoxia-ischemia (HI) brain injury, but its primary mechanisms remain uncertain1. We hypothesize that HI induces, whereas hypothermia represses, uncoupling of oxidative-phosphorylation (OXPHOS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79e6f36d5a50633add69e0650c29e91f
https://doi.org/10.1101/2021.11.29.470404
https://doi.org/10.1101/2021.11.29.470404
Autor:
Ton DeGrauw, Yuancheng Li, Xiaohui Zhang-Brotzge, Hui Mao, Elizabeth M. Fugate, Chia-Yi Kuan, Pasko Rakic, Hong-Ru Chen, Yury M. Morozov, Yu-Yo Sun, Irena S. Kuan, Siming Wang, Helen Heju Zhang, Diana M. Lindquist
Publikováno v:
JCI Insight
The creatine transporter (CrT) maintains brain creatine (Cr) levels, but the effects of its deficiency on energetics adaptation under stress remain unclear. There are also no effective treatments for CrT deficiency, the second most common cause of X-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402f35678a4814bd4fcc0017ba50b842
https://doi.org/10.1172/jci.insight.140173
https://doi.org/10.1172/jci.insight.140173
Autor:
Elizabeth M. Fugate, Chandrashekhar R. Gandhi, Jonathan R. Dillman, Akanksha Sharma, Jiang Wang, Diana M. Lindquist
Publikováno v:
Journal of magnetic resonance imaging : JMRIREFERENCES. 54(3)
BACKGROUND An imaging method that allows quantitative fibrosis estimates is needed to facilitate the diagnosis of chronic liver disease. Amide proton transfer (APT) and tissue sodium concentration (TSC) estimates could meet this need. HYPOTHESIS APT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ff985c4a4d13fdff947582b07f53aa
https://pubmed.ncbi.nlm.nih.gov/33738856
https://pubmed.ncbi.nlm.nih.gov/33738856
Autor:
Maziyar Keshavarzian, Mohammed Arif, Diana M. Lindquist, Sakthivel Sadayappan, Reza Avazmohammadi, Vy Chu, Elizabeth M. Fugate, Saurabh Chavan
Publikováno v:
Functional Imaging and Modeling of the Heart ISBN: 9783030787097
FIMH
Funct Imaging Model Heart
FIMH
Funct Imaging Model Heart
Accurate and efficient quantification of cardiac motion offers promising biomarkers for non-invasive diagnosis and prognosis of structural heart diseases. Cine cardiac magnetic resonance imaging remains one of the most advanced imaging tools to provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b666625de11cbec24fc33b111c8bd377
https://doi.org/10.1007/978-3-030-78710-3_27
https://doi.org/10.1007/978-3-030-78710-3_27
Autor:
Peter J, Niedbalski, Alexander S, Cochran, Matthew S, Freeman, Jinbang, Guo, Elizabeth M, Fugate, Cory B, Davis, Jerry, Dahlke, James D, Quirk, Brian M, Varisco, Jason C, Woods, Zackary I, Cleveland
Publikováno v:
Magn Reson Med
PURPOSE: Diffusion and lung morphometry imaging using hyperpolarized (3)He and (129)Xe are promising tools to quantify pulmonary microstructure noninvasively in humans and animal models. These techniques assume the motion encoded is exclusively diffu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::870e8977ee0d158297720ec9919044e7
https://pubmed.ncbi.nlm.nih.gov/33017076
https://pubmed.ncbi.nlm.nih.gov/33017076