Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elizabeth Laureen Strevel"'
Publikováno v:
European Journal of Cancer. 45:318-331
Over the last decade, molecularly targeted drugs have become established in oncology therapeutics and clinical research. While initially marketed as “cancer specific” agents with superior toxicity profiles to conventional anti-proliferative and D
Autor:
Caroline Domerg, Ming-Sound Tsao, Frances A. Shepherd, Stephen L. Graziano, Sinead Cuffe, Elizabeth Laureen Strevel, Monia Ezzalfani, Pasi A. Jänne, Marzia Capelletti, Lesley Seymour, Ronald Burkes, Abderrahmane Bourredjem, Jean-Pierre Pignon
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 7(6)
Introduction The staging of node-negative non–small-cell lung cancer is modified in the 7th edition TNM classification. Here, we pool data from the National Cancer Institute of Canada Clinical Trials Group JBR.10 trial and the Cancer and Leukemia G
Autor:
Eric Nadler, Peter A. Ubel, William K. Evans, Jennifer A. Palmer, Peter J. Neumann, Scott R. Berry, Chaim M. Bell, Elizabeth Laureen Strevel, Michael A. Kozminski
Publikováno v:
Health affairs (Project Hope). 31(4)
Amid calls for physicians to become better stewards of the nation's health care resources, it is important to gain insight into how physicians think about the cost-effectiveness of new treatments. Expensive new cancer treatments that can extend life
New anticancer drugs are improving outcomes for patients with cancer but at significant cost, and some publically funded health care systems have chosen not to fund these medications. Accessing these unfunded drugs concerns patients, challenges their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db224e0dbe25297cb264d1987f7a9ffa
https://europepmc.org/articles/PMC3266314/
https://europepmc.org/articles/PMC3266314/
Autor:
Eric Nadler, Peter J. Neumann, William K. Evans, Scott R. Berry, Peter A. Ubel, Chaim M. Bell, Elizabeth Laureen Strevel
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 28(27)
Purpose Oncologists in the United States and Canada work in different health care systems, but physicians in both countries face challenges posed by the rising costs of cancer drugs. We compared their attitudes regarding the costs and cost-effectiven
Autor:
Jeff Myers, Arun Partridge, Elizabeth Laureen Strevel, Katherine Enright, Cindy L. Quinton, Leonard Kaizer, Sudhashree Rajagopal, Mark Rother
Publikováno v:
Journal of Clinical Oncology. 31:e17503-e17503
e17503 Background: The standard of care for stage III colon cancer remains 5FU based AC. In clinical trial settings, this begins within 56 days of surgery. Recently a meta-analysis suggested that delays to starting chemotherapy are associated with in
Autor:
Elizabeth Laureen Strevel, Daliah Tsoref, Amit M. Oza, Helen Mackay, L. Austin Doyle, Gini F. Fleming, Robert M. Wenham, David R. Gandara, Stephen Welch, Robert J. Morgan, Helen X. Chen, Mark H. Einstein, Joseph A. Sparano, Briant Fruth, Daniel C. Sullivan, Rui Qin, Charles Erlichman, Hal W. Hirte, Molly Brewer
Publikováno v:
Journal of Clinical Oncology. 31:5517-5517
5517 Background: Anti-angiogenic therapy is active in OC; the combination of VEGF and mTOR inhibitors is hypothesized to further improve activity. This report is the OC cohort of a multi-histology phase II study assessing the activity and toxicity of
Autor:
Lisa Wang, Gini F. Fleming, Elizabeth Laureen Strevel, Ivan Diaz-Padilla, Stephen Welch, James Joseph Biagi, Anne Eisenhauer, Michael Reedijk, Amit M. Oza, Jennifer S. Li, Helen Mackay, Hal W. Hirte, S. Percy Ivy, Blaise A. Clarke, Johanne I Weberpals
Publikováno v:
Journal of Clinical Oncology. 30:5019-5019
5019 Background: Notch signalling pathway plays a critical role in regulating cellular differentiation, proliferation, and apoptosis in preclinical cancer models. The Notch receptor, its ligands, and down-stream effectors are over-expressed in OC. In
Autor:
Elizabeth Laureen Strevel, Mihaela C. Cristea, Mark H. Einstein, Rui Qin, Amit M. Oza, Robert M. Wenham, Andreas Kaubisch, Robert J. Morgan, Briant Fruth, Charles Erlichman
Publikováno v:
Journal of Clinical Oncology. 30:5025-5025
5025 Background: We report the interim results of the endometrial arm of a multi-tumor protocol using temsirolimus and bevacizumab in endometrial cancer (EMCA) patients at the time of their initial recurrence. The primary aim of this trial is to asse
Autor:
K. M. Laumann, L. A. Doyle, David R. Gandara, Charles Erlichman, Robert M. Wenham, Daniel C. Sullivan, Stephen Welch, Rui Qin, Helen X. Chen, Helen Mackay, Rebecca L. Morgan, Elizabeth Laureen Strevel, Amit M. Oza
Publikováno v:
Journal of Clinical Oncology. 29:5015-5015
5015 Background: Antiangiogenic therapy has activity in OC. The combination of vegf and mTOR inhibitior is hypothesized to improve activity. This study is performed to assess the activity and toxicity of tem/bev in patients with recurrent OC. Methods