Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elizabeth L. Wainwright"'
Autor:
Edward Geisinger, Germán Vargas-Cuebas, Nadav J. Mortman, Sapna Syal, Yunfei Dai, Elizabeth L. Wainwright, David Lazinski, Stephen Wood, Zeyu Zhu, Jon Anthony, Tim van Opijnen, Ralph R. Isberg
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT The emergence of fluoroquinolone resistance in nosocomial pathogens has restricted the clinical efficacy of this antibiotic class. In Acinetobacter baumannii, the majority of clinical isolates now show high-level resistance due to mutations
Externí odkaz:
https://doaj.org/article/1509ec34b30745a8b0fd843a51447f90
Autor:
Zeyu Zhu, Elizabeth L. Wainwright, Tim van Opijnen, Ralph R. Isberg, Nadav J. Mortman, Germán Vargas-Cuebas, Stephen Wood, David W. Lazinski, Jon Anthony, Yunfei Dai, Sapna Syal, Edward Geisinger
Publikováno v:
mBio
mBio, Vol 10, Iss 3, p e01127-19 (2019)
mBio, Vol 10, Iss 3 (2019)
mBio, Vol 10, Iss 3, p e01127-19 (2019)
mBio, Vol 10, Iss 3 (2019)
Fluoroquinolones have been extremely successful antibiotics due to their ability to target multiple bacterial enzymes critical to DNA replication, the topoisomerases DNA gyrase and topo IV. Unfortunately, mutations lowering drug affinity for both enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0870da5f0c9fe50996ed4dbb0e08c83c
https://pubmed.ncbi.nlm.nih.gov/31186328
https://pubmed.ncbi.nlm.nih.gov/31186328
Autor:
Ralph R. Isberg, Elizabeth L. Wainwright, Nadav J. Mortman, Zeyu Zhu, Stephen Wood, Sapna Syal, David W. Lazinski, Jon Anthony, Germán Vargas-Cuebas, Edward Geisinger, Tim van Opijnen
The emergence of fluoroquinolone resistance in nosocomial pathogens has restricted the clinical efficacy of this antibiotic class. InAcinetobacter baumannii, the majority of clinical isolates now show high-level resistance due to mutations ingyrA(DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8acc46e9b1ceaf5f9184e67e1456dd
https://doi.org/10.1101/442681
https://doi.org/10.1101/442681
