Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Elizabeth L Isaac"'
Autor:
Tomáš Čejka, Elizabeth L Isaac, Daniel Oliach, Fernando Martínez-Peña, Simon Egli, Paul Thomas, Miroslav Trnka, Ulf Büntgen
Publikováno v:
Environmental Research Letters, Vol 17, Iss 2, p 024001 (2022)
Climate change has been described as the main threat for the cultivation and growth of truffles, but hydroclimate variability and model uncertainty challenge regional projections and adaptation strategies of the emerging sector. Here, we conduct a li
Externí odkaz:
https://doaj.org/article/fa129f4c978e4684b699a120685b3f11
Publikováno v:
Microorganisms, Vol 8, Iss 10, p 1625 (2020)
Coffee is one of the most traded commodities in the world. It plays a significant role in the global economy, employing over 125 million people. However, it is possible that this vital crop is threatened by changing climate conditions and fungal infe
Externí odkaz:
https://doaj.org/article/546694252e994a09b1119bdd7d0b34ac
Autor:
Elizabeth L. Isaac
Publikováno v:
Organic Syntheses. 99:381-400
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::353255da720f7783a7d4af3c29318b3d
https://doi.org/10.15227/orgsyn.099.0381
https://doi.org/10.15227/orgsyn.099.0381
Autor:
Virginie Molinier, Ludger Sproll, Tomáš Čejka, Rengert Elburg, Martina Peter, Willy Tegel, Ulf Büntgen, Ulrich Stobbe, Elizabeth L. Isaac, Simon Egli
Publikováno v:
Fungal biology. 125(12)
Despite its status as a highly-prized and coveted fungi in gastronomy, many aspects of the subterranean life cycle of the Burgundy truffle (Tuber aestivum) are still unknown, because in situ observations of the formation and maturation of truffle fru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974158551a9fa37362eac4767f3eea77
https://pubmed.ncbi.nlm.nih.gov/34776232
https://pubmed.ncbi.nlm.nih.gov/34776232
Autor:
Greg Hodge, Litsa Karageorgos, Tom Litjens, Chi T. Hua, Melissa Chang, Elizabeth L. Isaac, Peter J. Meikle
Publikováno v:
Biochemical Journal. 382:481-489
LAMP-1 (lysosome-associated membrane protein), a major glycoprotein present in the lysosomal membrane, constitutes up to 50% of total membrane proteins. LAMP-1, expressed at the plasma membrane, is reported to be the major molecule expressing the sia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71a70bfd46584d608d26e08c2fe39b1
https://doi.org/10.1042/bj20031752
https://doi.org/10.1042/bj20031752
Autor:
Elizabeth L. Isaac, Doug A. Brooks, Peter J. Meikle, John J. Hopwood, Miao Yan, Elaine M. Ravenscroft
Publikováno v:
Molecular Genetics and Metabolism. 66:179-188
The lysosome-associated membrane protein (LAMP-1) is elevated in the cells and plasma from lysosomal storage disorder-affected individuals; however, the mechanism of this elevation is not well defined. In this study we have investigated the synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0f66c11b755ca904610794190ff450
https://doi.org/10.1006/mgme.1998.2800
https://doi.org/10.1006/mgme.1998.2800
Autor:
Litsa Karageorgos, Doug A. Brooks, Richard Davey, Elaine M. Ravenscroft, Elizabeth L. Isaac, Peter J. Meikle, John J. Hopwood
Publikováno v:
Experimental Cell Research. 234:85-97
Lysosomal biogenesis is an orchestration of the structural and functional elements of the lysosome to form an integrated organelle and involves the synthesis, targeting, functional residence, and turnover of the proteins that comprise the lysosome. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bf2252d8d914f74e7c28ae4929f4e3
https://doi.org/10.1006/excr.1997.3581
https://doi.org/10.1006/excr.1997.3581
Autor:
John J. Hopwood, Don S. Anson, Doug A. Brooks, Birgit A. Petersen, Elizabeth L. Isaac, Allison C. Crawley, Alison J. Moore, Nick L. Fazzalari, Barbara King, Vivienne Muller, Julie Bielicki, Sharon Byers, Christine D. Boulter
Publikováno v:
Journal of Clinical Investigation. 97:1864-1873
We report studies that suggest enzyme replacement therapy will result in a significant reduction in disease progression and tissue pathology in patients with Maroteaux-Lamy syndrome (Mucopolysaccharidosis type VI, MPS VI). A feline model for MPS VI w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2bc1158f10771c84abc70deb738d1c
https://doi.org/10.1172/jci118617
https://doi.org/10.1172/jci118617
Publikováno v:
Experimental cell research. 254(2)
Lysosomal biogenesis is a complex process requiring the coordinated expression and colocalization of numerous soluble and membrane proteins. In storage disorders, lysosomal biogenesis is regulated at least partially at, or prior to, the level of mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557204c8470cd43e8f18654c258c9aee
https://pubmed.ncbi.nlm.nih.gov/10640418
https://pubmed.ncbi.nlm.nih.gov/10640418
Autor:
Allison C. Crawley, K. H. Niedzielski, Sharon Byers, John J. Hopwood, Elizabeth L. Isaac, R. C. A. Davey
Publikováno v:
The Journal of clinical investigation. 99(4)
We report evidence of a dose responsive effect of enzyme replacement therapy in mucopolysaccharidosis type VI cats from birth, at the clinical, biochemical, and histopathological level. Cats treated with weekly, intravenous recombinant human N-acetyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c73ef451d4b5d7648b505cf937dd25a
https://pubmed.ncbi.nlm.nih.gov/9045867
https://pubmed.ncbi.nlm.nih.gov/9045867