Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elizabeth Koury"'
Publikováno v:
Revista de Defesa da Concorrência, Vol 10, Iss 1 (2022)
Contextualização: Com o advento das novas tecnologias da informação e comunicação, surge o questionamento sobre a necessidade, ou não, de evolução dos conceitos e das interpretações tradicionais do direito antitruste, para que este ramo do
Externí odkaz:
https://doaj.org/article/985b6e36332448c5972ef60efd0cc237
Autor:
Suzy Elizabeth Koury
Publikováno v:
Prim@ Facie, Vol 20, Iss 45 (2021)
Este artigo visa a discutir e analisar se cláusulas normativas derrogatórias de direitos dos trabalhadores harmonizam-se com a CRFB/88 e com os tratados e convenções internacionais reconhecidos no ordenamento jurídico brasileiro, ao privilegiare
Externí odkaz:
https://doaj.org/article/76432d701bbf48f1a30ef035df0978af
Autor:
Stephen Todd Cohn, Garth T. Whiteside, Darlene C. Deecher, Grace H. Johnston, Paige Erin Mahaney, Valerie Smith, Scott Cosmi, Puwen Zhang, Elizabeth Koury, Eugene John Trybulski, Kim Callain Younghee, Jenifer A. Bray, Liza Leventhal, An T. Vu, Jeffrey D. Kennedy, James E. Harrison
Publikováno v:
Journal of Medicinal Chemistry. 53:2051-2062
Efforts to identify new selective and potent norepinephrine reuptake inhibitors (NRIs) for multiple indications by structural modification of the previous 3-(arylamino)-3-phenylpropan-2-olamine scaffold led to the discovery of a novel series of 1-(in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d38a82f4c68b40baf4a429e77967f7
https://doi.org/10.1021/jm901559e
https://doi.org/10.1021/jm901559e
Autor:
Paige Erin Mahaney, Elizabeth Koury, Thomas Kenney, Robert Emmett Mcdevitt, Richard C. Winneker, Gavin David Heffernan, Grace H. Johnston, Darlene C. Deecher, Eugene John Trybulski, Christine Huselton, Peter D. Alfinito, Jenifer A. Bray, Scott Cosmi, Albert J. Robichaud, Eric S. Manas, Yanfang Li, Coghlan Richard Dale
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:7802-7815
The discovery of a series of 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles, dual acting norepinephrine reuptake inhibitors (NRIs) and 5-HT2A receptor antagonists, is described. The synthesis and structure–activity relationship (SAR) of this novel seri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438ee4ec8736e798e77eeb3492481070
https://doi.org/10.1016/j.bmc.2009.09.023
https://doi.org/10.1016/j.bmc.2009.09.023
Autor:
Casey Cameron Mccomas, Jenifer A. Bray, Cheryl A. Mugford, Puwen Zhang, Terefenko Eugene Anthony, Eugene John Trybulski, An T. Vu, Andrew Fensome, Garth T. Whiteside, Elizabeth Koury, Lilly Mark, Jim Harrison, Darlene C. Deecher, Paige Erin Mahaney, Kim Callain Younghee
Publikováno v:
Journal of Medicinal Chemistry. 52:5703-5711
Sequential structural modifications of the aryloxypropanamine template (e.g., atomoxetine, 2) led to a novel series of 1-(3-amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors (NRIs). In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc387e88a81026305a6f4d591b56022
https://doi.org/10.1021/jm900888c
https://doi.org/10.1021/jm900888c
Autor:
Casey Cameron Mccomas, Paige E. Mahaney, Darlene C. Deecher, Grace H. Johnston, Terefenko Eugene Anthony, Eugene John Trybulski, Elizabeth Koury, Puwen Zhang, An Vu, Jenifer A. Bray
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:6067-6070
A series of novel 1- or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors was discovered. Several compounds such as 15 and 20 showed good hNET potency. Compounds 15 and 20 also displayed ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10d315d14d5a7dfa8fd5b0e8d81e04c
https://doi.org/10.1016/j.bmcl.2008.10.026
https://doi.org/10.1016/j.bmcl.2008.10.026
Autor:
Jennifer Leiter, An T. Vu, Yingru Zhang, Sharon Rosenzweig-Lipson, Fei Ye, Valerie Smith, Stephen Todd Cohn, Douglas M. Ho, Elizabeth Koury, Justin K. Belardi, Darlene C. Deecher, Cheryl A. Mugford, Grace H. Johnston, Gary Paul Stack, Kevin D. Burroughs, Eugene John Trybulski, Scott Cosmi, Jenifer A. Bray, Joseph Peter Sabatucci, Lori Krim Gavrin, Liza Leventhal, Paige Erin Mahaney, Brian J. Platt, Arthur A. Santilli
Publikováno v:
Journal of Medicinal Chemistry. 51:4038-4049
Further exploration of the cycloalkanol ethylamine scaffold, of which venlafaxine ( 1) is a member, was undertaken to develop novel and selective norepinephrine reuptake inhibitors (NRIs) for evaluation in a variety of predictive animal models. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1714c4c78e768fe2426cceb434cdd1c4
https://doi.org/10.1021/jm8002262
https://doi.org/10.1021/jm8002262
Autor:
Fei Ye, Lisa Nogle, Andrew Fensome, Darlene C. Deecher, Michael Anthony Marella, Jenifer A. Bray, Stephen Todd Cohn, Peter D. Alfinito, Puwen Zhang, Eugene John Trybulski, Grace H. Johnston, Casey Cameron Mccomas, An T. Vu, Paige E. Mahaney, Elizabeth Koury
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:4929-4931
Norepinephrine and serotonin play an important role in a wide variety of biological processes and are implicated in a number of neurological disorders. A novel class of 1-(3-amino-1-phenylpropyl)indolin-2-ones was designed and synthesized that displa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bfeaeb02372c7c9aeaff273c9424ec
https://doi.org/10.1016/j.bmcl.2008.08.060
https://doi.org/10.1016/j.bmcl.2008.08.060
Autor:
Darlene C. Deecher, Thomas J. Berrodin, Sunil Nagpal, Aaron C. Pawlyk, Christa L. Smolenski, Elizabeth Koury
Publikováno v:
Steroids. 74(2)
Thyroid hormone receptors (TRs) are nuclear receptors that are activated by thyroid hormone ligands and co-regulator proteins. Two receptor subtypes, TRalpha and TRbeta, have been suggested to play a role in numerous physiological functions. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d451ee1a12fc351157d6dee89a9145
https://pubmed.ncbi.nlm.nih.gov/19073200
https://pubmed.ncbi.nlm.nih.gov/19073200
Autor:
Puwen Zhang, Eugene A. Terefenko, Jenifer Bray, Darlene Deecher, Andrew Fensome, Jim Harrison, Callain Kim, Elizabeth Koury, Lilly Mark, Casey C. McComas, Cheryl A. Mugford, Eugene J. Trybulski, An T. Vu, Garth T. Whiteside, Paige E. Mahaney
Publikováno v:
Journal of Medicinal Chemistry; Sep2009, Vol. 52 Issue 18, p5703-5711, 9p