Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Elizabeth K. Symes"'
Publikováno v:
Clinica Chimica Acta. 272:149-157
An association between allelic variants in the vitamin D receptor gene and bone mineral density has been previously described. A bimodal variation in the rate of bone resorption (as measured by urinary deoxypyridinoline excretion rate) has also been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852a4f868b9ae96fca869d3dd52e3a31
https://doi.org/10.1016/s0009-8981(98)00016-3
https://doi.org/10.1016/s0009-8981(98)00016-3
Publikováno v:
Biochemical Pharmacology. 44:741-746
Certain oestrogens on substitution with halogens, have been shown to retain receptor binding affinity and accumulate in target tissues and therefore could, when labelled with gamma-emitting halogen isotope, act as radiopharmaceuticals for the imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5e87bbbc89a85ded0516d4a3f83544e
https://doi.org/10.1016/0006-2952(92)90411-b
https://doi.org/10.1016/0006-2952(92)90411-b
Publikováno v:
Clinical Endocrinology. 35:447-451
Summary. objective In fetuses, adrenal steroids have been Implicated In organ maturation and in some species in initiation of labour. The fetal adrenal gland differs from the adult in its complement of steroid metabolizing enzymes. This study sought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4128f4092eefc944972d73f2b4607b8d
https://doi.org/10.1111/j.1365-2265.1991.tb03564.x
https://doi.org/10.1111/j.1365-2265.1991.tb03564.x
Publikováno v:
Journal of Steroid Biochemistry. 35:641-646
16α-Iodo-oestradiol binds with high affinity to the oestrogen receptor and has been shown to accumulate in oestrogen sensitive tissues in many test systems. We have prepared the compound labelled with 131 I at four specific activities. Using these p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636912260feb4b678ee6a47bf325274e
https://doi.org/10.1016/0022-4731(90)90303-a
https://doi.org/10.1016/0022-4731(90)90303-a
Publikováno v:
Journal of Steroid Biochemistry. 25:359-365
Vitamin B6 deficient female rats showed a significantly earlier, greater and more prolonged uptake of a tracer dose of [3H]oestradiol into the uterus, with increased nuclear accumulation, compared with vitamin B6 supplemented animals. This was most m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08365916a7fb6ee6002e8fc46330795
https://doi.org/10.1016/0022-4731(86)90248-7
https://doi.org/10.1016/0022-4731(86)90248-7
Autor:
Elizabeth K. Symes
Publikováno v:
Biochemical Pharmacology. 31:3231-3236
Elucidation of the mechanism whereby androgens are accumulated selectively by the prostate may help in the design of drugs for the treatment of prostatic cancer. The uptake and retention of [3H]testosterone, following intraperitoneal injection, by va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f55deef3e65ef4c8c1d07644c2467f
https://doi.org/10.1016/0006-2952(82)90555-x
https://doi.org/10.1016/0006-2952(82)90555-x
Publikováno v:
Journal of Steroid Biochemistry. 20:1089-1093
Six-week old male rats were maintained for 4 weeks on a vitamin B6-free diet to cause a moderately severe degree of vitamin B6 depletion. This led to a significant reduction in the circulating concentration of testosterone in plasma (control = 8.36 +
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044c50381f04c998d3895c1141bcdd7d
https://doi.org/10.1016/0022-4731(84)90348-0
https://doi.org/10.1016/0022-4731(84)90348-0
Publikováno v:
Journal of Urology. 120:180-183
An in vitro test system suitable to assess the potency of putative antiandrogens has been developed, using the human benign prostatic tissue obtained at operation. The system circumvents some problems associated with using human tissue, such as the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ee158f17e6b1431482fe3889f9d9d5
https://doi.org/10.1016/s0022-5347(17)57095-0
https://doi.org/10.1016/s0022-5347(17)57095-0
Publikováno v:
Journal of Steroid Biochemistry. 18:161-165
Rats were depleted of vitamin B6 by treatment with isoniazid, and then maintained on diets providing: no vitamin B6, an adequate amount (1.2 mg/kg diet) or a very large amount (120 mg/kg) for 5 weeks. The uptake of a tracer dose of [3H]-oestradiol in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6778a193c5d4c5cf00814d3134bac560
https://doi.org/10.1016/0022-4731(83)90082-1
https://doi.org/10.1016/0022-4731(83)90082-1
Publikováno v:
European journal of cancer. 12(5)
Studies on plasma dehydroepiandrosterone (DHEA) concentrations employing a new gas chromatographic analytical method with electron capture detection were performed on women with breast cancer and benign breast disease. Significantly lower values were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b7c6ecc80e2f776381515e4cb4e53e
https://pubmed.ncbi.nlm.nih.gov/133803
https://pubmed.ncbi.nlm.nih.gov/133803