Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Elizabeth K. O'Donnell"'
Autor:
Catherine R. Marinac, Katelyn Downey, Jacqueline Perry, Brittany Fisher-Longden, Timothy R. Rebbeck, Urvi A. Shah, Elizabeth K. O’Donnell, Irene M. Ghobrial, Omar Nadeem, Brian L. Egleston
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/361e1a0693ad4996ad7867b16bfc3805
Autor:
David J Lee, Elizabeth K O'Donnell, Noopur Raje, Cristina Panaroni, Robert Redd, Jennifer Ligibel, Dorothy D Sears, Omar Nadeem, Irene M Ghobrial, Catherine R Marinac
Publikováno v:
JMIR Research Protocols, Vol 13, p e51368 (2024)
BackgroundObesity is an established, modifiable risk factor of multiple myeloma (MM); yet, no lifestyle interventions are routinely recommended for patients with overweight or obesity with MM precursor conditions. Prolonged nightly fasting is a simpl
Externí odkaz:
https://doaj.org/article/2337909fc38a47099368b1c9f66691d9
Autor:
Clifton C. Mo, Andrew J. Yee, Shonali Midha, Monique A. Hartley‐Brown, Omar Nadeem, Elizabeth K. O'Donnell, Giada Bianchi, Adam S. Sperling, Jacob P. Laubach, Paul G. Richardson
Publikováno v:
eJHaem, Vol 4, Iss 3, Pp 792-810 (2023)
Abstract Selinexor is an orally bioavailable selective inhibitor of nuclear export compound that inhibits exportin‐1 (XPO1), a novel therapeutic target that is overexpressed in multiple myeloma (MM) and is responsible for the transport of ∼220 nu
Externí odkaz:
https://doaj.org/article/df6d5d22d8aa4c3088dccaac48019fd0
Autor:
Kevin Charles Miller, Patrick Connor Johnson, Jeremy S. Abramson, Jacob D. Soumerai, Andrew J. Yee, Andrew R. Branagan, Elizabeth K. O’Donnell, Anna Saucier, Caron A. Jacobson, Matthew J. Frigault, Noopur S. Raje
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 10, Pp 1-12 (2022)
Abstract Chimeric antigen receptor T cells (CAR T) are groundbreaking therapies but may cause significant toxicities including cytokine release syndrome (CRS), immune effector cell-associated neurotoxicity syndrome (ICANS), and cytopenias. Granulocyt
Externí odkaz:
https://doaj.org/article/3228817cf75c47368f94792a61f6aa4d
Autor:
Pouneh K. Fazeli, Miriam A. Bredella, Gisela Pachon-Peña, Wenxiu Zhao, Xun Zhang, Alexander T. Faje, Megi Resulaj, Sai P. Polineni, Tara M. Holmes, Hang Lee, Elizabeth K. O’Donnell, Ormond A. MacDougald, Mark C. Horowitz, Clifford J. Rosen, Anne Klibanski
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
BACKGROUND Adipocytes were long considered inert components of the bone marrow niche, but mouse and human models suggest bone marrow adipose tissue (BMAT) is dynamic and responsive to hormonal and nutrient cues.METHODS In this study of healthy volunt
Externí odkaz:
https://doaj.org/article/f9b9b856c1e14301bb81e9b24e87630a
Autor:
Matthew J. Frigault, Michael R. Bishop, Jacalyn Rosenblatt, Elizabeth K. O’Donnell, Noopur Raje, Daniella Cook, Andrew J. Yee, Emma Logan, David E. Avigan, Andrzej Jakubowiak, Kit Shaw, Heather Daley, Sarah Nikiforow, Faith Griffin, Christine Cornwell, Angela Shen, Christopher Heery, Marcela V. Maus
Publikováno v:
Blood Advances. 7:768-777
Relapsed and refractory multiple myeloma (RRMM) is a plasma cell neoplasm defined by progressively refractory disease necessitating chronic and increasingly intensive therapy. Despite recent advances, limited treatment options exist for RRMM. This si
Autor:
Elizabeth K. O'Donnell, Yael N. Shapiro, Amy Comander, Steven J. Isakoff, Beverly Moy, Laura Spring, Seth Wander, Irene Kuter, Jennifer Shin, Jerry Younger, Michelle Specht, Chryssanthi Kourniotis, Carol Sullivan, Loren Winters, Nora Horick, Jeffrey Peppercorn
Publikováno v:
Cancer Research. 82:PD5-11
Background: Prior, retrospective analysis of nightly fasting among women with breast cancer suggests that fasting less than 13 hours per night may be associated with higher risk of breast cancer recurrence. Small studies suggest that fasting duration
Autor:
Elizabeth K. O’Donnell, Yael N. Shapiro, Andrew J. Yee, Omar Nadeem, Jacob P. Laubach, Andrew R. Branagan, Kenneth C. Anderson, Clifton C. Mo, Nikhil C. Munshi, Irene M. Ghobrial, Adam S. Sperling, Emerentia A. Agyemang, Jill N. Burke, Cynthia C. Harrington, Bonnie Y. Hu, Paul G. Richardson, Noopur S. Raje, Areej El-Jawahri
Publikováno v:
Blood Advances. 6:4967-4974
Although caregivers of patients with multiple myeloma (MM) play a critical role in supporting their loved ones throughout the illness course, studies examining caregiver quality of life (QOL), psychological distress, and prognostic awareness are lack
Autor:
Andrew R. Branagan, Matthew M Lei, Clifton C Mo, Andrew J. Yee, Elizabeth K. O'Donnell, Jorge J. Castillo, Omar Nadeem, Noopur Raje, Steven P Treon, Paul G. Richardson, Rie Nakamoto-Matsubara, Kirsten Meid, Zachary S. Bernstein, Rebecca T. Lyons, Rakesh Verma, Zachary R Hunter, Maria Luisa Guerrera, Catherine A. Flynn, Jill N. Burke, Cynthia C. Harrington, Emerentia Agyemang, Marilyn T. Gammon, Kathleen J. Lively, Lisette Packer, Nora K. Horick, Shayna Sarosiek
Publikováno v:
Blood. 140:10094-10096
Autor:
Elizabeth K. O’Donnell, Yael N. Shapiro, Andrew J. Yee, Omar Nadeem, Bonnie Y. Hu, Jacob P. Laubach, Andrew R. Branagan, Kenneth C. Anderson, Clifton C. Mo, Nikhil C. Munshi, Irene M. Ghobrial, Adam S. Sperling, Emerentia A. Agyemang, Jill N. Burke, Cynthia C. Harrington, Paul G. Richardson, Noopur S. Raje, Areej El‐Jawahri
Publikováno v:
Cancer. 128:1996-2004
Multiple myeloma (MM) is an incurable hematologic malignancy requiring long-term, continuous therapy. Despite its chronic and unrelenting course, studies examining quality of life (QOL), psychological distress, and perceptions of prognosis by line of