Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elizabeth K. Lacy"'
Autor:
J. David Robertson, Patrick M. Winter, John S. Allen, Samuel A. Wickline, Elizabeth K. Lacy, Grace Hu, Shelton D. Caruthers, Todd A. Williams, Thomas D. Harris, Gregory M. Lanza, Anne M. Neubauer, Huiying Zhang, Anne H. Schmieder
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 26:2103-2109
Objective— Angiogenic expansion of the vasa vasorum is a well-known feature of progressive atherosclerosis, suggesting that antiangiogenic therapies may stabilize or regress plaques. α ν β 3 Integrin–targeted paramagnetic nanoparticles were pr
Autor:
Michael J. Scott, J. David Robertson, Samuel A. Wickline, Todd A. Williams, Shelton D. Caruthers, Thomas D. Harris, Patrick M. Winter, Elizabeth K. Lacy, Grace Hu, Anne H. Schmieder, John S. Allen, Huiying Zhang, Gregory M. Lanza
Publikováno v:
Magnetic Resonance in Medicine. 53:621-627
Neovascularization is a critical component in the progression of malignant melanoma. The objective of this study was to determine whether alpha(nu)beta(3)-targeted paramagnetic nanoparticles can detect and characterize sparse alpha(nu)beta integrin e
Autor:
Elizabeth K. Lacy, A.K. Woodson, Jon N. Marsh, H. Zhang, Michael S. Hughes, S.A. Wickline, John S. Allen, Gregory M. Lanza, C. Carradine
Publikováno v:
IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 53(9)
We describe characterization of backscatter from tumor tissue targeted with a nanoparticle-based ultrasound contrast agent in vivo using analogs of thermodynamic quantities. We apply these waveform characteristics to detection of tumor neovasculature
Autor:
John S. Allen, H. Zhang, Anne M. Morawski, Shelton D. Caruthers, Ralph W. Fuhrhop, Jon N. Marsh, Patrick M. Winter, S.A. Wickline, Michael J. Scott, Gregory M. Lanza, Elizabeth K. Lacy, Grace Hu, Anne H. Schmieder, Michael S. Hughes
Publikováno v:
ACS Symposium Series ISBN: 9780841239180
Molecular imaging agents are extending the potential of non-invasive medical diagnosis from basic gross anatomical descriptions to complicated phenotypic characterizations, based upon the recognition of unique cell-surface biochemical signatures. Ori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f23ddc7e05f19dddbbcfdc8576a3bf2
https://doi.org/10.1021/bk-2006-0923.ch021
https://doi.org/10.1021/bk-2006-0923.ch021
Autor:
Jon N. Marsh, Michael S. Hughes, Elizabeth K. Lacy, John S. Allen, Christopher S. Hall, Samuel A. Wickline, Michael J. Scott, Peggy A. Brown, Gregory M. Lanza
Publikováno v:
IEEE Ultrasonics Symposium, 2004.
Angiogenesis has been postulated as an important marker for the early detection of cancer. The proteins associated with new vessels are sub-resolution for ultrasonic imaging, necessitating the use of contrast agents. In this work we use a liquid, per
Autor:
Michael J. Scott, Jon N. Marsh, Elizabeth K. Lacy, K.C. Crowder, Michael S. Hughes, Gregory M. Lanza, S.A. Wickline
Publikováno v:
IEEE Ultrasonics Symposium, 2004.
Liquid perfluorocarbon nanoparticle contrast agents can be used to target specific tissue types through incorporation of appropriate ligands into the nanoparticles' outer lipid monolayer. In this study we sought to characterize the specificity of tar
Autor:
Ralph W. Fuhrhop, Jon N. Marsh, Elizabeth K. Lacy, Michael S. Hughes, Christopher S. Hall, Gregory M. Lanza, Samuel A. Wickline
Publikováno v:
The Journal of the Acoustical Society of America. 117(2)
The ability to enhance specific molecular markers of pathology with ultrasound has been previously demonstrated by our group employing a nanoparticle contrast agent [Lanza et al., Invest. Radiol. 35, 227–234 (2000); Ultrasound Med. Biol. 23, 863–
Autor:
Anne H, Schmieder, Patrick M, Winter, Shelton D, Caruthers, Thomas D, Harris, Todd A, Williams, John S, Allen, Elizabeth K, Lacy, Huiying, Zhang, Michael J, Scott, Grace, Hu, J David, Robertson, Samuel A, Wickline, Gregory M, Lanza
Publikováno v:
Magnetic resonance in medicine. 53(3)
Neovascularization is a critical component in the progression of malignant melanoma. The objective of this study was to determine whether alpha(nu)beta(3)-targeted paramagnetic nanoparticles can detect and characterize sparse alpha(nu)beta integrin e
Autor:
John S. Allen, Michael J. Scott, Elizabeth K. Lacy, Michael S. Hughes, Jon N. Marsh, Gregory M. Lanza, Samuel A. Wickline, Huiying Zhang
Publikováno v:
AIP Conference Proceedings.
Advances in molecular biology and cellular biochemistry are providing new opportunities for diagnostic medical imaging to “see” beyond the anatomical manifestations of disease to the earliest biochemical signatures of disease. Liquid perfluorocar
Autor:
Huiying Zhang, Gregory M. Lanza, John S. Allen, Elizabeth K. Lacy, Ralph W. Fuhrhop, Todd A. Williams, Anne M. Morawski, Samuel A. Wickline, Shelton D. Caruthers, J. David Robertson, Patrick M. Winter
Publikováno v:
Circulation. 108(18)
Background— Angiogenesis is a critical feature of plaque development in atherosclerosis and might play a key role in both the initiation and later rupture of plaques that lead to myocardial infarction and stroke. The precursory molecular or cellula