Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elizabeth K. Hendrickson"'
Publikováno v:
Analytical Biochemistry. 276:27-35
Phospholipase substrate analogs containing both a fluorescent BODIPY group and a quenching 2,4-dinitrophenyl (DNP) group were synthesized. They showed little fluorescence, but upon hydrolysis became fluorescent as the quenching group was removed. Two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b476d93cd721639a4f5706e165e6b9da
https://doi.org/10.1006/abio.1999.4280
https://doi.org/10.1006/abio.1999.4280
Publikováno v:
Bioorganic & Medicinal Chemistry. 2:147-151
The synthesis of optically-active hexadecyl thiophosphoryl-1- d -myo-inositol 11 was accomplished from 2,3-O-( d -1′,7′,7′-trimethyl[2.2.1]bicyclohept-2′-ylidene)-4,5,6-O-tris(methoxymethyl)- d -myo-inositol 6 or 2,3,4,5,6-O-pentakis(methoxym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f04c8adc54c4c319d64dea0ebf0d02
https://doi.org/10.1016/s0968-0896(00)82010-6
https://doi.org/10.1016/s0968-0896(00)82010-6
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 1:615-618
Racemic hexadecylthiophosphoryl-1-myo-inositol was synthesized from a pentaprotected inositol-1-dimethylphosphite and hexadecylthiophthalimide in a Michaelis-Arbuzov reaction. It was shown to be a good substrate for the assay of phosphatidylinositol-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f4495b97b44252ba99ef1a8cb12eb8e
https://doi.org/10.1016/s0960-894x(01)81163-x
https://doi.org/10.1016/s0960-894x(01)81163-x
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 1:619-622
Racemic 4-(1-pyreno)butylphosphoryl-1-myo-inositol was synthesized from a pentaprotected inositol-1-dimethylphosphite by phosphite coupling with 4-(1-pyreno)butanol. It is a good substrate for a very sensitive assay of phosphatidylinositol-specific p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f502f95c5f477e67a8fee7f75da89108
https://doi.org/10.1016/s0960-894x(01)81164-1
https://doi.org/10.1016/s0960-894x(01)81164-1
Publikováno v:
Chemistry and Physics of Lipids. 53:115-120
Trityl-glycidol was synthesized by in situ derivatization of glycidol, which was prepared by the catalytic asymmetric epoxidation of allyl alcohol. Depending on the enantiomer of diisopropyl tartrate used with the titanium catalyst, either ( R )- or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffc5c06819d27039c8fc42f9e6b88bd
https://doi.org/10.1016/0009-3084(90)90139-i
https://doi.org/10.1016/0009-3084(90)90139-i
Publikováno v:
Analytical Biochemistry. 185:80-83
Two fluorescent phospholipid analogs, 1-O-{12-(2-naphthyl)-dodec-11-enyl}-2-O-decanoyl-sn-glycero-3-phosphocholine and dansyl-PC [rac 1-O-(N-dansyl-11-amino-1-undecyl)-2-O-decanoyl-glycero-3-phosphocholine], and a red-colored analog, dabsyl-PC [rac 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2e4298d2754b2f513b459d01ab5268
https://doi.org/10.1016/0003-2697(90)90258-b
https://doi.org/10.1016/0003-2697(90)90258-b
Autor:
Mary C. Mullins, Michael Pack, H.Stewart Hendrickson, Elizabeth K. Hendrickson, Marnie E. Halpern, Shiu Ying Ho, Daniel S. Wagner, Steven A. Farber, Iain Johnson, Roland Dosch
Publikováno v:
Science (New York, N.Y.). 292(5520)
Zebrafish are a valuable model for mammalian lipid metabolism; larvae process lipids similarly through the intestine and hepatobiliary system and respond to drugs that block cholesterol synthesis in humans. After ingestion of fluorescently quenched p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e4c385c4cb7b65dcb47b5997844a7d
https://pubmed.ncbi.nlm.nih.gov/11359013
https://pubmed.ncbi.nlm.nih.gov/11359013
Publikováno v:
Chemistry and physics of lipids. 109(2)
In search of an efficient method to prepare cholinephosphate headgroups in phospholipids under mild conditions (where the diacylglycerol moiety is not subject to oxidation), a method was developed for phosphorylation using a trialkyl phosphite and I2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0562833ec2cdfc1b8c576a128aa17a1a
https://pubmed.ncbi.nlm.nih.gov/11269938
https://pubmed.ncbi.nlm.nih.gov/11269938
Publikováno v:
Biochimica et biophysica acta. 1440(1)
Dissociation constants for binding of phosphatidylinositol-specific phospholipase C from Bacillus cereus (bcPI-PLC) and the mammalian phosphatidylinositol-specific phospholipase C-delta(1) to lipid interfaces containing phosphoinositol, phosphocholin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad692963bca537e26e0763b655420a2e
https://pubmed.ncbi.nlm.nih.gov/10477830
https://pubmed.ncbi.nlm.nih.gov/10477830
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(9)
1,2-Dimyristoyloxypropane-3-thiophosphate(rac-1-myo-inositol-4- phosphate), a thiophosphate analog of dimyristoyl phosphatidylinositol-4-phosphate was synthesized as a substrate for mammalian phosphoinositide-specific phospholipase C. Its activity wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1efac61fcc9f5e05664c766a2eb5cc
https://pubmed.ncbi.nlm.nih.gov/9871707
https://pubmed.ncbi.nlm.nih.gov/9871707