Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Elizabeth K Wheeler"'
Autor:
Jose Cadena, Ana Paula Sales, Doris Lam, Heather A Enright, Elizabeth K Wheeler, Nicholas O Fischer
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 5, p e1007834 (2020)
Neurons form complex networks that evolve over multiple time scales. In order to thoroughly characterize these networks, time dependencies must be explicitly modeled. Here, we present a statistical model that captures both the underlying structural a
Externí odkaz:
https://doaj.org/article/f359b178d0224a089a3eb228b7c4b7e6
Autor:
Doris Lam, Heather A. Enright, Jose Cadena, Vivek Kurien George, David A. Soscia, Angela C. Tooker, Michael Triplett, Sandra K. G. Peters, Piyush Karande, Alexander Ladd, Chandrakumar Bogguri, Elizabeth K. Wheeler, Nicholas O. Fischer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/46bf1bf290a6473294bc10f5300da66c
Autor:
Doris Lam, Heather A. Enright, Jose Cadena, Vivek Kurien George, David A. Soscia, Angela C. Tooker, Michael Triplett, Sandra K. G. Peters, Piyush Karande, Alexander Ladd, Chandrakumar Bogguri, Elizabeth K. Wheeler, Nicholas O. Fischer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
While there is a growing appreciation of three-dimensional (3D) neural tissues (i.e., hydrogel-based, organoids, and spheroids), shown to improve cellular health and network activity to mirror brain-like activity in vivo, functional assessment using
Externí odkaz:
https://doaj.org/article/3d854a25be3a4aa590525715e4cbe6c1
Autor:
Aimy Sebastian, Kelly A. Martin, Ivana Peran, Nicholas R. Hum, Nicole F. Leon, Beheshta Amiri, Stephen P. Wilson, Matthew A. Coleman, Elizabeth K. Wheeler, Stephen W. Byers, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the top five deadliest forms of cancer with very few treatment options. The 5-year survival rate for PDAC is 10% following diagnosis. Cadherin 11 (Cdh11), a cell-to-cell adhesion molecule, has been su
Externí odkaz:
https://doaj.org/article/50a6f40489714f8794e255c10b83ab8d
Autor:
Elisa Marie Wasson, Wei He, Jesse Ahlquist, William Fredrick Hynes, Michael Gregory Triplett, Aubree Hinckley, Eveliina Karelehto, Delaney Ruth Gray-Sherr, Caleb Fisher Friedman, Claire Robertson, Maxim Shusteff, Robert Warren, Matthew A. Coleman, Monica Lizet Moya, Elizabeth K. Wheeler
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
There is an urgent need to develop new therapies for colorectal cancer that has metastasized to the liver and, more fundamentally, to develop improved preclinical platforms of colorectal cancer liver metastases (CRCLM) to screen therapies for efficac
Externí odkaz:
https://doaj.org/article/7e566eb0389d4bdfbdc8662124047118
Autor:
Nicholas R. Hum, Aimy Sebastian, Kelly A. Martin, Naiomy D. Rios-Arce, Sean F. Gilmore, David M. Gravano, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Due to lack of targetable receptors and intertumoral heterogeneity, triple negative breast cancer (TNBC) remains particularly difficult to treat. Doxorubicin (DOX) is typically used as nonselective neoadjuvant chemotherapy, but the diversity of treat
Externí odkaz:
https://doaj.org/article/c68fb0a68f6b4394a52c6b409b8dbd81
Autor:
Dennis C. Freeman, Monica L. Moya, Christopher M. Spadaccini, Angela C. Tooker, Daniel N. Wang, Elizabeth K. Wheeler, Eric B. Duoss, Monica K. Borucki, Greg Larsen, Maxim Shusteff
Publikováno v:
Mrs Bulletin
At the start of the COVID-19 pandemic, the US faced nationwide shortages of nasopharyngeal swabs due to both overwhelmed supply chains and an increase in demand. To address this shortfall, multiple 3D printed swabs were ultimately produced and sold f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4922680343da44e5408b15a517f6a872
http://europepmc.org/articles/PMC8437332
http://europepmc.org/articles/PMC8437332
Publikováno v:
Diagnostics, Vol 3, Iss 1, Pp 105-116 (2013)
Development of new diagnostic platforms that incorporate lab-on-a-chip technologies for portable assays is driving the need for rapid, simple, low cost methods to prepare samples for downstream processing or detection. An important component of the s
Externí odkaz:
https://doaj.org/article/8eaec8e8da234b988cae6975b67a5505
Autor:
Nicholas R. Hum, Doris Lam, Bryan Petkus, Heather A. Enright, Kristen S. Kulp, Joanne Osburn, Elizabeth K. Wheeler, David A. Soscia, Sandra K. G. Peters, Ana Paula Sales, Jose Cadena, Nicholas O. Fischer, Gabriela G. Loots, Aimy Sebastian
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, vol 10, iss 1
Brain-on-a-chip systems are designed to simulate brain activity using traditional in vitro cell culture on an engineered platform. It is a noninvasive tool to screen new drugs, evaluate toxicants, and elucidate disease mechanisms. However, successful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d8db6a32e53d3d63360194e401cb83
http://link.springer.com/article/10.1038/s41598-020-67691-2
http://link.springer.com/article/10.1038/s41598-020-67691-2
Autor:
Claire Robertson, Aimy Sebastian, Aubree Hinckley, Naiomy D. Rios-Arce, William F. Hynes, Skye A. Edwards, Wei He, Nicholas R. Hum, Elizabeth K. Wheeler, Gabriela G. Loots, Matthew A. Coleman, Monica L. Moya
Publikováno v:
Biomaterials. 282
Despite the success of T cell checkpoint therapies, breast cancers rarely express these immunotherapy markers and are believed to be largely "immune cold" with limited inflammation and immune activation. The reason for this limited immune activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97b1472053f6d91cf6b492829d2082f
https://pubmed.ncbi.nlm.nih.gov/35121359
https://pubmed.ncbi.nlm.nih.gov/35121359